# Domain Associates' Biotech Investments: 33 Startups in Its Portfolio (2026)

> The 33 Biotech startups Domain Associates has backed, by stage: $2.8B raised between them. From the rounds we track; updated nightly.

Source: https://millionrounds.com/portfolio-maps/domain-associates-biotech-portfolio (Millionrounds; every figure on the page links to its filing or article)

## Series C and later

12

- [aTyr Pharma](https://millionrounds.com/company/atyr-pharma)
- [*RB* Regado Biosciences](https://millionrounds.com/company/regado-biosciences)
- [ReVision Optics](https://millionrounds.com/company/revision-optics)
- [IntegenX](https://millionrounds.com/company/integenx)
- [Aspen Neuroscience](https://millionrounds.com/company/aspen-neuroscience)
- [Sera Prognostics](https://millionrounds.com/company/sera-prognostics)
- [Truvian Sciences](https://millionrounds.com/company/truvian-sciences)
- [CellBiosciences](https://millionrounds.com/company/cellbiosciences)
- [*RM* ROX Medical](https://millionrounds.com/company/rox-medical)
- [GenVault](https://millionrounds.com/company/genvault)
- [*N* Novacea](https://millionrounds.com/company/novacea)
- [Novalar Pharmaceuticals](https://millionrounds.com/company/novalar-pharmaceuticals)

## Stage not reported

8

- [Celladon](https://millionrounds.com/company/celladon)
- [*S* Sebacia](https://millionrounds.com/company/sebacia)
- [Somaxon Pharmaceuticals](https://millionrounds.com/company/somaxon-pharmaceuticals)
- [Meritage Pharma](https://millionrounds.com/company/meritage-pharma)
- [ChromaCode](https://millionrounds.com/company/chromacode)
- [*ST* Sonexa Therapeutics](https://millionrounds.com/company/sonexa-therapeutics)
- [*H* Helixis](https://millionrounds.com/company/helixis)
- [*NB* Nina Biotherapeutics](https://millionrounds.com/company/nina-biotherapeutics)

## Series B

7

- [Milestone Pharmaceuticals](https://millionrounds.com/company/milestone-pharmaceuticals)
- [Atara Biotherapeutics](https://millionrounds.com/company/atara-biotherapeutics)
- [*X* Xagenic](https://millionrounds.com/company/xagenic)
- [*AB* Axial Biotherapeutics](https://millionrounds.com/company/axial-biotherapeutics)
- [NovaDigm Therapeutics](https://millionrounds.com/company/novadigm-therapeutics)
- [*W* WindML](https://millionrounds.com/company/windml)
- [*A* Adynxx](https://millionrounds.com/company/adynxx)

## Growth

3

- [Epic Sciences](https://millionrounds.com/company/epic-sciences)
- [GI Dynamics](https://millionrounds.com/company/gi-dynamics)
- [*FP* Five Prime Therapeutics](https://millionrounds.com/company/five-prime-therapeutics)

## Series A

3

- [*CT* CoDa Therapeutics](https://millionrounds.com/company/coda-therapeutics)
- [Optherion](https://millionrounds.com/company/optherion)
- [Sequel Pharmaceuticals](https://millionrounds.com/company/sequel-pharmaceuticals)

## Segment by segment

### Series C and later

12 startups · $1.3B raised

- [**aTyr Pharma**](https://millionrounds.com/company/atyr-pharma) aTyr Pharma (Nasdaq: LIFE) is a biotherapeutics company engaged in the discovery and development of innovative medicines based on United States $181M
- [*RB* **Regado Biosciences**](https://millionrounds.com/company/regado-biosciences) Regado Biosciences develops antithrombotic drug systems for acute and sub-acute cardiovascular and other indications. United States $177M
- [**ReVision Optics**](https://millionrounds.com/company/revision-optics) ReVision Optics offers PRESBYLENS, a refractive surgery solution to correct vision loss by the natural aging process. United States $172M
- [**IntegenX**](https://millionrounds.com/company/integenx) IntegenX designs, manufactures and markets automation systems facilitating reliable micro sample preparation and analysis. United States $161M
- [**Aspen Neuroscience**](https://millionrounds.com/company/aspen-neuroscience) Aspen Neuroscience is a biotechnology company that specializes in personalized cell therapies. United States $122M
- [**Sera Prognostics**](https://millionrounds.com/company/sera-prognostics) Sera Prognostics develops blood tests that are predictive of preterm birth, preeclampsia, and other pregnancy complications. United States $107M
- [**Truvian Sciences**](https://millionrounds.com/company/truvian-sciences) Truvian Sciences develops an automated benchtop system to provide lab-accurate blood testing results. United States $101M
- [**CellBiosciences**](https://millionrounds.com/company/cellbiosciences) ProteinSimple develops and commercializes proprietary systems and consumables for protein analyzis. United States $85M

### Stage not reported

8 startups · $532M raised

- [**Celladon**](https://millionrounds.com/company/celladon) Celladon is a biotechnology company developing molecular therapies for the treatment of heart failure. United States $172M
- [*S* **Sebacia**](https://millionrounds.com/company/sebacia) Sebacia is a commercial-stage dermatology company that develops an alternative to the topical and systemic drugs for the treatment of acne. United States $102M
- [**Somaxon Pharmaceuticals**](https://millionrounds.com/company/somaxon-pharmaceuticals) Somaxon Pharmaceuticals is a growing specialty pharmaceutical company dedicated to commercializing proprietary branded prescriptio United States $94M
- [**Meritage Pharma**](https://millionrounds.com/company/meritage-pharma) Meritage Pharma develops prescription products for the treatment of gastrointestinal and atopic diseases. United States $59M
- [**ChromaCode**](https://millionrounds.com/company/chromacode) ChromaCode is a molecular diagnostics company focusing on bioinformatics. United States $44M
- [*ST* **Sonexa Therapeutics**](https://millionrounds.com/company/sonexa-therapeutics) United States $41M
- [*H* **Helixis**](https://millionrounds.com/company/helixis) Helixis, Inc. United States $17M
- [*NB* **Nina Biotherapeutics**](https://millionrounds.com/company/nina-biotherapeutics) Nina Biotherapeutics develops therapies to combat cachexia in cancer patients. United States $3.5M

### Series B

7 startups · $391M raised

- [**Milestone Pharmaceuticals**](https://millionrounds.com/company/milestone-pharmaceuticals) Milestone Pharmaceuticals is a drug development company developing small molecule therapeutics for the treatment of cardiovascular diseases. Canada $110M
- [**Atara Biotherapeutics**](https://millionrounds.com/company/atara-biotherapeutics) Atara Biotherapeutics (Nasdaq: ATRA) is an off-the-shelf, allogeneic T-cell immunotherapy company. United States $69M
- [*X* **Xagenic**](https://millionrounds.com/company/xagenic) Xagenic is a molecular diagnostics company developing on-demand molecular testing, facilitating faster treatment decisions for patients. Canada $67M
- [*AB* **Axial Biotherapeutics**](https://millionrounds.com/company/axial-biotherapeutics) United States $54M
- [**NovaDigm Therapeutics**](https://millionrounds.com/company/novadigm-therapeutics) NovaDigm Therapeutics develops vaccines that protect patients from contracting fungal and bacterial infections. United States $35M
- [*W* **WindML**](https://millionrounds.com/company/windml) United States $33M
- [*A* **Adynxx**](https://millionrounds.com/company/adynxx) United States $24M

### Growth

3 startups · $467M raised

- [**Epic Sciences**](https://millionrounds.com/company/epic-sciences) Epic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine. United States $165M
- [**GI Dynamics**](https://millionrounds.com/company/gi-dynamics) GI Dynamics is a medical device company developing therapies for the treatment of type 2 diabetes and related metabolic diseases. United States $156M
- [*FP* **Five Prime Therapeutics**](https://millionrounds.com/company/five-prime-therapeutics) FivePrime is a clinical-stage biotechnology company that develops treatments for cancers. United States $146M

### Series A

3 startups · $145M raised

- [*CT* **CoDa Therapeutics**](https://millionrounds.com/company/coda-therapeutics) United States $78M
- [**Optherion**](https://millionrounds.com/company/optherion) Optherion, Inc., a biotechnology company, develops diagnostic and disease-modifying therapeutics for the management and treatment United States $42M
- [**Sequel Pharmaceuticals**](https://millionrounds.com/company/sequel-pharmaceuticals) Sequel Pharmaceuticals develops and commercializes novel and clinical-stage drug candidates for patients with cardiovascular disease. United States $25M

**How this map is made.** Every startup here works in Biotech and has raised money in a round we track that names Domain Associates as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Co-investors **Who invests with Domain Associates** 46 co-investors](https://millionrounds.com/portfolio-maps/domain-associates-co-investors)[Sector portfolio **Techstars' AI portfolio** 336 startups · $4.9B](https://millionrounds.com/portfolio-maps/techstars-ai-portfolio)[Sector portfolio **Alumni Ventures' AI portfolio** 302 startups · $36B](https://millionrounds.com/portfolio-maps/us-strategic-tech-fund-an-alumni-ventures-fund-ai-portfolio)[Sector portfolio **Andreessen Horowitz's AI portfolio** 259 startups · $426B](https://millionrounds.com/portfolio-maps/andreessen-horowitz-ai-portfolio)[Sector portfolio **General Catalyst's AI portfolio** 226 startups · $179B](https://millionrounds.com/portfolio-maps/general-catalyst-ai-portfolio)[Sector portfolio **Sequoia Capital's AI portfolio** 209 startups · $543B](https://millionrounds.com/portfolio-maps/sequoia-capital-ai-portfolio)

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