# De Novo Ventures' Biotech Investments: 10 Startups in Its Portfolio (2026)

> The 10 Biotech startups De Novo Ventures has backed, by stage: $793M raised between them. From the rounds we track; updated nightly.

Source: https://millionrounds.com/portfolio-maps/de-novo-ventures-biotech-portfolio (Millionrounds; every figure on the page links to its filing or article)

## Series B

4

- [Renovis](https://millionrounds.com/company/renovis)
- [*SS* Sierra Surgical](https://millionrounds.com/company/sierra-surgical)
- [*O* Ovalis](https://millionrounds.com/company/ovalis)
- [*C* Cartilix](https://millionrounds.com/company/cartilix)

## Series C and later

4

- [Avedro](https://millionrounds.com/company/avedro)
- [*L* Lumend](https://millionrounds.com/company/lumend)
- [*IS* iScience Surgical](https://millionrounds.com/company/iscience-surgical)
- [*F* FlowMedica](https://millionrounds.com/company/flowmedica)

## Stage not reported

2

- [EndoGastric Solutions](https://millionrounds.com/company/endogastric-solutions)
- [EBR Systems](https://millionrounds.com/company/ebr-systems)

## Segment by segment

### Series B

4 startups · $71M raised

- [**Renovis**](https://millionrounds.com/company/renovis) Renovis,is a biopharmaceutical company developing drugs to treat neurological diseases and disorders. United States $34M
- [*SS* **Sierra Surgical**](https://millionrounds.com/company/sierra-surgical) Sieraa Surgical develops minimally-invasive surgical systems based on female sterilization technologies. United States $22M
- [*O* **Ovalis**](https://millionrounds.com/company/ovalis) Ovalis is a biotechnology company that develops catheter-based medical devices for the repair of cardiovascular defects. United States $8.5M
- [*C* **Cartilix**](https://millionrounds.com/company/cartilix) Cartilix develops and commercializes biomaterials to repair damaged tissues in articular joints and other applications. United States $6.3M

### Series C and later

4 startups · $269M raised

- [**Avedro**](https://millionrounds.com/company/avedro) Avedro is a medical device and pharmaceutical company advancing the science and technology of corneal cross-linking. United States $203M
- [*L* **Lumend**](https://millionrounds.com/company/lumend) Lumend is a Health Care company. - $23M
- [*IS* **iScience Surgical**](https://millionrounds.com/company/iscience-surgical) Iscience Surgical develops and offers high resolution imaging systems and microsurgical instruments. United States $22M
- [*F* **FlowMedica**](https://millionrounds.com/company/flowmedica) FlowMedica is a medical device company which produces intravascular systems for implementing targeted renal therapy. United States $21M

### Stage not reported

2 startups · $454M raised

- [**EndoGastric Solutions**](https://millionrounds.com/company/endogastric-solutions) EndoGastric Solutions is a medical device company based in Redmond, Washington. United States $293M
- [**EBR Systems**](https://millionrounds.com/company/ebr-systems) EBR Systems is a provider of wireless cardiac pacing system for millions of patients suffering from cardiac rhythm diseases. United States $161M

**How this map is made.** Every startup here works in Biotech and has raised money in a round we track that names De Novo Ventures as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Sector portfolio **Citibank's Fintech portfolio** 79 startups · $17B](https://millionrounds.com/portfolio-maps/citi-fintech-portfolio)[Sector portfolio **RTW Investments LLC's Biotech portfolio** 52 startups · $11B](https://millionrounds.com/portfolio-maps/rtw-investments-lp-biotech-portfolio)[Sector portfolio **Citibank's AI portfolio** 50 startups · $64B](https://millionrounds.com/portfolio-maps/citi-ai-portfolio)[Sector portfolio **Bond's AI portfolio** 31 startups · $15B](https://millionrounds.com/portfolio-maps/bond-ai-portfolio)[Sector portfolio **S2G Investments' Agtech portfolio** 22 startups · $891M](https://millionrounds.com/portfolio-maps/s2g-investments-agtech-portfolio)[Sector portfolio **Celgene's Biotech portfolio** 17 startups · $3.2B](https://millionrounds.com/portfolio-maps/celgene-biotech-portfolio)

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