# Solo angels backing Biotech (2026 list) > 45 solo angels backing Biotech, 76% active in the last 12 months. Led by 500 Global, Edward Lando, Alexis Ohanian. Ranked by what they funded. Source: https://millionrounds.com/lists/solo-angels-biotech (Millionrounds; every figure on the page links to its filing or article) [Investor Lists](https://millionrounds.com/lists) # Solo angels backing Biotech Updated 7 November 2026 Solo angels we have observed in a biotech round in the last two years. [See all 45 *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fsolo-angels-biotech)The top 25 **45** investors on the list *+1* this week **202** cheques in 12 months *-28%* against the market **$35M** median round they joined *+338%* against the market median **76%** wrote a cheque in 12 months **16%** have led a round ## The Top 25 Ordered by cheques observed, never by anything anyone paid for Deploying now (20) - 1 [500 Global](https://millionrounds.com/fund/500-startups) *Deploying now* Angel · United States **2,140** **$3.6M** median round **Oct 2026** last seen - 2 [Edward Lando](https://millionrounds.com/fund/edward-lando) *Deploying now* Angel · United States **179** **$3.5M** median round **Jul 2026** last seen - 3 [Alexis Ohanian](https://millionrounds.com/fund/alexis-ohanian) *Deploying now* Angel · United States **132** **$39M** median round **Jul 2026** last seen - 4 [Gokul Rajaram](https://millionrounds.com/fund/gokul-rajaram) *Deploying now* Angel · United States **100** **$8M** median round **Nov 2026** last seen - 5 [Sam Altman](https://millionrounds.com/fund/sam-altman) *Deploying now* Angel · United States **82** **$15M** median round **Jun 2026** last seen - 6 [Jeff Dean](https://millionrounds.com/fund/jeff-dean) *Deploying now* Angel · United States **65** **$9.6M** median round **Oct 2026** last seen - 7 [Garry Tan](https://millionrounds.com/fund/garry-tan) *Deploying now* Angel · United States **62** **$38M** median round **Jun 2026** last seen - 8 [Simon Murdoch](https://millionrounds.com/fund/daniel-gross) quiet Angel · United Kingdom **41** **$22M** median round **May 2025** last seen - 9 [Lachy Groom](https://millionrounds.com/fund/lachy-groom) *Deploying now* Angel · United States **37** **$12M** median round **Oct 2026** last seen - 10 [Jeff Bezos](https://millionrounds.com/fund/jeff-bezos) *Deploying now* Angel · United States **33** **$490M** median round **Jul 2026** last seen - 11 [Danish Chaudhry](https://millionrounds.com/fund/danish-chaudhry) *Deploying now* Angel · United Kingdom **30** **$6.4M** median round **Oct 2026** last seen - 12 [Patrick Collison](https://millionrounds.com/fund/patrick-collison) *Deploying now* Angel · United States **17** **$60M** median round **Nov 2026** last seen - 13 [Joshua Kushner](https://millionrounds.com/fund/joshua-kushner) quiet Angel **8** **$130M** median round **May 2025** last seen - 14 [Mike Krieger](https://millionrounds.com/fund/mike-krieger) *Deploying now* Angel **7** **$41M** median round **Oct 2026** last seen - 15 [John Collison](https://millionrounds.com/fund/john-collison) *Deploying now* Angel **6** **$37M** median round **Oct 2026** last seen - 16 [Dylan Field](https://millionrounds.com/fund/dylan-field) *Deploying now* Angel **5** **$125M** median round **Oct 2026** last seen - 17 [Iqram Magdon-Ismail](https://millionrounds.com/fund/iqram-magdon-ismail) *Deploying now* Angel **5** **$14M** median round **Jun 2026** last seen - 18 [Jimmy Iovine](https://millionrounds.com/fund/jimmy-iovine) *Deploying now* Angel **3** **$700M** median round **Jul 2026** last seen - 19 [Ion Stoica](https://millionrounds.com/fund/ion-stoica) *Deploying now* Angel **3** **$40M** median round **Oct 2026** last seen - 20 [Steve Aoki](https://millionrounds.com/fund/steve-aoki) quiet Angel **3** **$35M** median round **Apr 2025** last seen - 21 [Tom Berry](https://millionrounds.com/fund/tom-berry) quiet Angel **3** **$12M** median round **May 2025** last seen - 22 [Ari Emanuel](https://millionrounds.com/fund/ari-emanuel) *Deploying now* Angel **2** **$700M** median round **Jul 2026** last seen - 23 [Bob Nelsen](https://millionrounds.com/fund/bob-nelsen) *Deploying now* Angel **2** **$110M** median round **Oct 2026** last seen - 24 [Carles Reina](https://millionrounds.com/fund/carles-reina) *Deploying now* Angel **2** **$45M** median round **Nov 2026** last seen - 25 [Logan Paul](https://millionrounds.com/fund/logan-paul) quiet Angel **2** **$30M** median round **Apr 2025** last seen **20 more on this list** All 45 are in the app, with filters for stage, sector and market. A free account shows 10 per search, Pro up to 1,000. [See the whole list *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fsolo-angels-biotech) ## The Newest Cheques Rounds this list's investors joined most recently - **5** Nov **[Siggy](https://millionrounds.com/company/siggy)** Pre-seed · $6M *With* [Gokul Rajaram](https://millionrounds.com/fund/gokul-rajaram) - **5** Nov **[Potential Sciences](https://millionrounds.com/company/potential-sciences)** Seed *With* [Patrick Collison](https://millionrounds.com/fund/patrick-collison) - **3** Nov **[Vitroscope](https://millionrounds.com/company/vitroscope)** Seed · $5M *With* [Carles Reina](https://millionrounds.com/fund/carles-reina) - **29** Oct **[Mintive](https://millionrounds.com/company/mintive)** Seed · $7M *With* [Jeff Dean](https://millionrounds.com/fund/jeff-dean) - **27** Oct **[Cancore](https://millionrounds.com/company/cancore)** Seed · $7.2M *With* [Danish Chaudhry](https://millionrounds.com/fund/danish-chaudhry) - **24** Oct **[Warhound](https://millionrounds.com/company/warhound)** Seed · $200M *With* [Bob Nelsen](https://millionrounds.com/fund/bob-nelsen) ## Stages This Year 182 rounds - Seed **33%** - Series A **19%** - Venture **14%** - Series B **8%** - Pre-seed **7%** - Other **20%** ## What They Backed Sectors, last 12 months - AI **91** - Biotech **22** - Fintech **15** - Healthcare **14** - Big Data & Analytics **10** - Software **9** ## Cheques by Quarter Led Joined 79 Q1 25 80 Q2 25 75 Q3 25 62 Q4 25 65 Q1 26 53 Q2 26 46 Q3 26 18 Q4 26 The last bar is the quarter still running. ## Lists Like This - [VC firms backing AI 4,329](https://millionrounds.com/lists/vc-firms-ai) - [VC firms backing Fintech 1,856](https://millionrounds.com/lists/vc-firms-fintech) - [VC firms backing Big Data & Analytics 1,248](https://millionrounds.com/lists/vc-firms-big-data) - [VC firms backing Biotech 1,207](https://millionrounds.com/lists/vc-firms-biotech) - [VC firms backing Robotics 1,098](https://millionrounds.com/lists/vc-firms-robotics) - [VC firms backing Construction 1,025](https://millionrounds.com/lists/vc-firms-construction) - [VC firms backing Energy 998](https://millionrounds.com/lists/vc-firms-energy) - [PE firms backing AI 956](https://millionrounds.com/lists/pe-firms-ai) - [VC firms backing Cybersecurity 950](https://millionrounds.com/lists/vc-firms-cybersecurity) [All investor lists *→*](https://millionrounds.com/lists) ## Reading for founders in health and biotech - The Innovator's Prescription: A Disruptive Solution for Health Care Clayton M. Christensen · 2008 4.21 from 1,158 ratings on Goodreads Health and biotech Innovation Moats and competition About the book A groundbreaking prescription for health care reform--from a legendary leader in innovation... Our health care system is in critical condition. Each year, fewer Americans can afford it, fewer businesses can provide it, and fewer government programs can promise it for future… On AmazonListen on Audible - Where Does It Hurt?: An Entrepreneur's Guide to Fixing Health Care Jonathan Bush · 2014 3.78 from 598 ratings on Goodreads Health and biotech Company building Innovation About the book A bold new remedy for the sprawling and wasteful health care industry Where else but the doctor’s office do you have to fill out a form on a clipboard? Have you noticed that hospital bills are almost unintelligible, except for the absurdly high dollar amount? Why is it that… On AmazonListen on Audible - Ashes to Ashes: America's Hundred-Year Cigarette War, the Public Health, and the Unabashed Triumph of Philip Morris Richard Kluger · 1997 3.94 from 306 ratings on Goodreads Health and biotech Company building About the book Ashes to Ashes is a monumental history of the American tobacco industry’s ironic success in developing the cigarette, modern society’s most widespread instrument of self-destruction, into the nation’s most profitable consumer product. Starting with its energized, work-obsessed… On AmazonListen on Audible - The Kelloggs: The Battling Brothers of Battle Creek Howard Markel · 2017 3.87 from 969 ratings on Goodreads Health and biotech Company building About the book "What's more American than Corn Flakes?" --Bing Crosby From the much admired medical historian ("Markel shows just how compelling the medical history can be"--Andrea Barrett) and author of An Anatomy of Addiction ("Absorbing, vivid"--Sherwin Nuland, The New York Times Book… On AmazonListen on Audible More books for founders and investors on the [Reading List](https://millionrounds.com/reading-list?role=founder&industry=health). As an Amazon Associate we earn from qualifying purchases. ## Quick answers about solo angels backing Biotech ### Who are the most active solo angels backing Biotech? By cheques observed, the most active are 500 Global, Edward Lando, Alexis Ohanian, Gokul Rajaram and Sam Altman. ### How many solo angels backing Biotech are there? 45 are on record. 76% made an investment in the last 12 months and 16% have led a round. ### Which stages do solo angels backing Biotech back? Of the rounds with a named stage in the last 12 months, mostly Seed (41%) and Series A (23%). ### How big are the rounds solo angels backing Biotech join? The typical (median) round among the leading investors here is $37M. ### Which sectors do solo angels backing Biotech back most? In the last 12 months, mostly AI, Biotech and Fintech. ### Which solo angels backing Biotech lead the most rounds? 500 Global (5 led), Lachy Groom (5 led) and Jeff Bezos (2 led). ### Where are solo angels backing Biotech based? Among the most active, most are based in the United States (10) and the United Kingdom (2). ### What have solo angels backing Biotech invested in recently? Recent rounds include Siggy (Pre-seed, Nov 2026, with Gokul Rajaram), Potential Sciences (Seed, Nov 2026, with Patrick Collison) and Vitroscope (Seed, Nov 2026, with Carles Reina). Built from the rounds we watched, refreshed every night. [How we count](https://millionrounds.com/methodology) · [Report a correction](https://millionrounds.com/corrections)