# Series B healthtech investors (2026 list)

> 111 series B healthtech investors, 86% active in the last 12 months. Led by Y Combinator, Alumni Ventures, Plug and Play. Ranked by what they funded.

Source: https://millionrounds.com/lists/series-b-healthtech-investors (Millionrounds; every figure on the page links to its filing or article)

[Investor Lists](https://millionrounds.com/lists)

# Series B healthtech investors

Updated 7 November 2026

Firms we have watched take part in a Series B round raised by a healthtech company in the last two years. Both the stage and the sector are what they did, not what their website says.

[See all 111 *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fseries-b-healthtech-investors)The top 25

**111** investors on the list *+15* this week

**4,199** cheques in 12 months *-7%* against the market

**$23M** median round they joined *+188%* against the market median

**86%** wrote a cheque in 12 months

**62%** have led a round

## The Top 25

Ordered by cheques observed, never by anything anyone paid for

Deploying now (25)

- 1 [Y Combinator](https://millionrounds.com/fund/y-combinator) *Deploying now* Accelerator · United States **6,412** **$3M** median round **Oct 2026** last seen
- 2 [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund) *Deploying now* VC firm · United States **1,598** **$12M** median round **Nov 2026** last seen
- 3 [Plug and Play](https://millionrounds.com/fund/plug-and-play) *Deploying now* Accelerator · United States **1,561** **$5M** median round **Nov 2026** last seen
- 4 [General Catalyst](https://millionrounds.com/fund/general-catalyst) *Deploying now* VC firm · United States **1,387** **$27M** median round **Nov 2026** last seen
- 5 [Accel](https://millionrounds.com/fund/accel) *Deploying now* VC firm · United States **1,341** **$32M** median round **Nov 2026** last seen
- 6 [Lightspeed Venture Partners](https://millionrounds.com/fund/lightspeed-venture-partners) *Deploying now* VC firm · United States **1,341** **$35M** median round **Nov 2026** last seen
- 7 [Khosla Ventures](https://millionrounds.com/fund/khosla-ventures) *Deploying now* VC firm · United States **1,128** **$26M** median round **Nov 2026** last seen
- 8 [Index Ventures](https://millionrounds.com/fund/index-ventures) *Deploying now* VC firm · United Kingdom **1,027** **$31M** median round **Nov 2026** last seen
- 9 [Gaingels](https://millionrounds.com/fund/gaingels) *Deploying now* Private equity · United States **1,010** **$8M** median round **Oct 2026** last seen
- 10 [Google Ventures](https://millionrounds.com/fund/gv) *Deploying now* Corporate VC · United States **884** **$38M** median round **Oct 2026** last seen
- 11 [FJ Labs](https://millionrounds.com/fund/fj-labs) *Deploying now* VC firm · United States **849** **$11M** median round **Oct 2026** last seen
- 12 [BoxGroup](https://millionrounds.com/fund/boxgroup) *Deploying now* VC firm · United States **773** **$18M** median round **Nov 2026** last seen
- 13 [Redpoint](https://millionrounds.com/fund/redpoint) *Deploying now* VC firm · United States **742** **$32M** median round **Nov 2026** last seen
- 14 [Menlo Ventures](https://millionrounds.com/fund/menlo-ventures) *Deploying now* VC firm · United States **740** **$37M** median round **Oct 2026** last seen
- 15 [Norwest Venture Partners](https://millionrounds.com/fund/norwest) *Deploying now* VC firm · United States **705** **$25M** median round **Oct 2026** last seen
- 16 [U.S. Venture Partners](https://millionrounds.com/fund/u-s-venture-partners-usvp) *Deploying now* VC firm · United States **535** **$15M** median round **Nov 2026** last seen
- 17 [Bain Capital Ventures](https://millionrounds.com/fund/bain-capital-ventures) *Deploying now* VC firm · United States **524** **$27M** median round **Nov 2026** last seen
- 18 [Polaris Partners](https://millionrounds.com/fund/polaris-partners) *Deploying now* VC firm · United States **490** **$36M** median round **Oct 2026** last seen
- 19 [Global Founders Capital](https://millionrounds.com/fund/global-founders-capital) *Deploying now* VC firm · Germany **461** **$7M** median round **Oct 2026** last seen
- 20 [Correlation Ventures](https://millionrounds.com/fund/correlation-ventures) *Deploying now* VC firm · United States **395** **$9M** median round **Nov 2026** last seen
- 21 [K Fund](https://millionrounds.com/fund/kfund) *Deploying now* VC firm · Spain **340** **$3M** median round **Oct 2026** last seen
- 22 [Entrepreneur First](https://millionrounds.com/fund/entrepreneurs-first) *Deploying now* Accelerator · United Kingdom **332** **$3.6M** median round **Oct 2026** last seen
- 23 [FirstMark](https://millionrounds.com/fund/firstmark) *Deploying now* VC firm · United States **319** **$20M** median round **Oct 2026** last seen
- 24 [Endeavor Catalyst](https://millionrounds.com/fund/endeavor-catalyst) *Deploying now* Corporate VC · United States **318** **$30M** median round **Oct 2026** last seen
- 25 [Headline](https://millionrounds.com/fund/headline) *Deploying now* VC firm · United States **307** **$15M** median round **Oct 2026** last seen

**86 more on this list**

All 111 are in the app, with filters for stage, sector and market. A free account shows 10 per search, Pro up to 1,000.

[See the whole list *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fseries-b-healthtech-investors)

## The Newest Cheques

Rounds this list's investors joined most recently

- **6** Nov **[Physicl](https://millionrounds.com/company/physicl)** Seed · $10M *With* [U.S. Venture Partners](https://millionrounds.com/fund/u-s-venture-partners-usvp)
- **6** Nov **[Thinking Machines Lab](https://millionrounds.com/company/thinking-machines-lab)** Other · $5B *Led by* [Accel](https://millionrounds.com/fund/accel)
- **5** Nov **[T-Therapeutics](https://millionrounds.com/company/t-therapeutics)** Series B · $133M *With* [Sofinnova Partners](https://millionrounds.com/fund/sofinnova-partners)
- **5** Nov **[Siggy](https://millionrounds.com/company/siggy)** Pre-seed · $6M *Led by* [Village Global](https://millionrounds.com/fund/village-global-2)
- **5** Nov **[firmly](https://millionrounds.com/company/firmly)** Series A · $15M *With* [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund)
- **5** Nov **[Alethio Therapeutics](https://millionrounds.com/company/alethio-therapeutics)** Series A · $90M *Led by* [Sofinnova Partners](https://millionrounds.com/fund/sofinnova-partners)

## Stages This Year

3,138 rounds

- Venture **20%**
- Seed **18%**
- Series A **17%**
- Pre-seed **11%**
- Series B **9%**
- Other **24%**

## What They Backed

Sectors, last 12 months

- AI **1,514**
- Fintech **235**
- Healthcare **189**
- Biotech **171**
- Big Data & Analytics **165**
- Financial Services **133**

## Cheques by Quarter

Led Joined

1,152 Q1 25

1,145 Q2 25

1,270 Q3 25

1,363 Q4 25

1,273 Q1 26

1,163 Q2 26

954 Q3 26

277 Q4 26

The last bar is the quarter still running.

## Lists Like This

- [Seed AI investors 2,922](https://millionrounds.com/lists/seed-ai-investors)
- [Series A AI investors 2,490](https://millionrounds.com/lists/series-a-ai-investors)
- [Series B AI investors 1,557](https://millionrounds.com/lists/series-b-ai-investors)
- [Pre-seed AI investors 1,286](https://millionrounds.com/lists/pre-seed-ai-investors)
- [Growth AI investors 1,186](https://millionrounds.com/lists/growth-ai-investors)
- [Series A fintech investors 950](https://millionrounds.com/lists/series-a-fintech-investors)
- [Series C AI investors 930](https://millionrounds.com/lists/series-c-ai-investors)
- [Seed fintech investors 925](https://millionrounds.com/lists/seed-fintech-investors)
- [Series A biotech investors 650](https://millionrounds.com/lists/series-a-biotech-investors)

[All investor lists *→*](https://millionrounds.com/lists)

## Reading for founders in health and biotech

- Silk Road Eileen Ormsby · 2014 3.99 from 548 ratings on Goodreads Health and biotech Company building About the book It was the 'eBay of drugs', a billion dollar empire. Behind it was the FBI's Most Wanted Man, a mysterious crime czar dubbed 'Dread Pirate Roberts'. SILK ROAD lay at the heart of the 'Dark Web' - a parallel internet of porn, guns, assassins and drugs. Lots of drugs. With the… On AmazonListen on Audible
- Where Does It Hurt?: An Entrepreneur's Guide to Fixing Health Care Jonathan Bush · 2014 3.78 from 598 ratings on Goodreads Health and biotech Company building Innovation About the book A bold new remedy for the sprawling and wasteful health care industry Where else but the doctor’s office do you have to fill out a form on a clipboard? Have you noticed that hospital bills are almost unintelligible, except for the absurdly high dollar amount? Why is it that… On AmazonListen on Audible
- The Kelloggs: The Battling Brothers of Battle Creek Howard Markel · 2017 3.87 from 969 ratings on Goodreads Health and biotech Company building About the book "What's more American than Corn Flakes?" --Bing Crosby From the much admired medical historian ("Markel shows just how compelling the medical history can be"--Andrea Barrett) and author of An Anatomy of Addiction ("Absorbing, vivid"--Sherwin Nuland, The New York Times Book… On AmazonListen on Audible
- The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America Allan M. Brandt · 2007 4.10 from 509 ratings on Goodreads Health and biotech Company building About the book The invention of mass marketing led to cigarettes being emblazoned in advertising and film, deeply tied to modern notions of glamour and sex appeal. It is hard to find a photo of Humphrey Bogart or Lauren Bacall without a cigarette. No product has been so heavily promoted or has… On AmazonListen on Audible

More books for founders and investors on the [Reading List](https://millionrounds.com/reading-list?role=founder&industry=health&stage=scaling).

As an Amazon Associate we earn from qualifying purchases.

## Quick answers about series B healthtech investors

### Who are the most active series B healthtech investors?

By cheques observed, the most active are Y Combinator, Alumni Ventures, Plug and Play, General Catalyst and Accel.

### How many series B healthtech investors are there?

111 are on record. 86% made an investment in the last 12 months and 62% have led a round.

### Which stages do series B healthtech investors back?

Of the rounds with a named stage in the last 12 months, mostly Seed (25%) and Series A (24%).

### How big are the rounds series B healthtech investors join?

The typical (median) round among the leading investors here is $20M.

### Which sectors do series B healthtech investors back most?

In the last 12 months, mostly AI, Fintech and Healthcare.

### Which series B healthtech investors lead the most rounds?

Accel (103 led), General Catalyst (97 led) and Lightspeed Venture Partners (83 led).

### Where are series B healthtech investors based?

Most of the leading investors here are based in the United States (21 of the top 25); the rest in the United Kingdom and Germany.

### What have series B healthtech investors invested in recently?

Recent rounds include Physicl (Seed, Nov 2026, with U.S. Venture Partners), Thinking Machines Lab (Other, Nov 2026, with Accel) and T-Therapeutics (Series B, Nov 2026, with Sofinnova Partners).

Built from the rounds we watched, refreshed every night. [How we count](https://millionrounds.com/methodology) · [Report a correction](https://millionrounds.com/corrections)