# Series B biotech investors (2026 list)

> 464 series B biotech investors, 92% active in the last 12 months. Led by Y Combinator, 500 Global, Sequoia Capital. Ranked by what they funded.

Source: https://millionrounds.com/lists/series-b-biotech-investors (Millionrounds; every figure on the page links to its filing or article)

[Investor Lists](https://millionrounds.com/lists)

# Series B biotech investors

Updated 7 November 2026

Firms we have watched take part in a Series B round raised by a biotech company in the last two years. Both the stage and the sector are what they did, not what their website says.

[See all 464 *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fseries-b-biotech-investors)The top 25

**464** investors on the list *+11* this week

**9,400** cheques in 12 months *-1%* against the market

**$30M** median round they joined *+275%* against the market median

**92%** wrote a cheque in 12 months

**60%** have led a round

## The Top 25

Ordered by cheques observed, never by anything anyone paid for

Deploying now (25)

- 1 [Y Combinator](https://millionrounds.com/fund/y-combinator) *Deploying now* Accelerator · United States **6,412** **$3M** median round **Oct 2026** last seen
- 2 [500 Global](https://millionrounds.com/fund/500-startups) *Deploying now* Angel · United States **2,140** **$3.6M** median round **Oct 2026** last seen
- 3 [Sequoia Capital](https://millionrounds.com/fund/sequoia-capital) *Deploying now* VC firm · United States **2,099** **$35M** median round **Nov 2026** last seen
- 4 [National Science Foundation](https://millionrounds.com/fund/nsf-small-business-innovation-research-small-business-techno) *Deploying now* Government · United States **1,869** **$926K** median round **Sept 2026** last seen
- 5 [Andreessen Horowitz](https://millionrounds.com/fund/andreessen-horowitz) *Deploying now* VC firm · United States **1,661** **$27M** median round **Nov 2026** last seen
- 6 [New Enterprise Associates](https://millionrounds.com/fund/new-enterprise-associates) *Deploying now* VC firm · United States **1,610** **$34M** median round **Oct 2026** last seen
- 7 [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund) *Deploying now* VC firm · United States **1,598** **$12M** median round **Nov 2026** last seen
- 8 [General Catalyst](https://millionrounds.com/fund/general-catalyst) *Deploying now* VC firm · United States **1,387** **$27M** median round **Nov 2026** last seen
- 9 [SV Angel](https://millionrounds.com/fund/sv-angel) *Deploying now* VC firm · United States **1,349** **$18M** median round **Oct 2026** last seen
- 10 [Bpifrance](https://millionrounds.com/fund/bpifrance) *Deploying now* Government · France **1,151** **$4.5M** median round **Oct 2026** last seen
- 11 [Khosla Ventures](https://millionrounds.com/fund/khosla-ventures) *Deploying now* VC firm · United States **1,128** **$26M** median round **Nov 2026** last seen
- 12 [Founders Fund](https://millionrounds.com/fund/founders-fund) *Deploying now* VC firm · United States **1,122** **$15M** median round **Oct 2026** last seen
- 13 [Bessemer Venture Partners](https://millionrounds.com/fund/bessemer-venture-partners) *Deploying now* VC firm · United States **1,038** **$30M** median round **Nov 2026** last seen
- 14 [Index Ventures](https://millionrounds.com/fund/index-ventures) *Deploying now* VC firm · United Kingdom **1,027** **$31M** median round **Nov 2026** last seen
- 15 [Gaingels](https://millionrounds.com/fund/gaingels) *Deploying now* Private equity · United States **1,010** **$8M** median round **Oct 2026** last seen
- 16 [Google Ventures](https://millionrounds.com/fund/gv) *Deploying now* Corporate VC · United States **884** **$38M** median round **Oct 2026** last seen
- 17 [EIC Accelerator](https://millionrounds.com/fund/eic-accelerator) *Deploying now* Government · European Union **875** **$4.3M** median round **Oct 2026** last seen
- 18 [BoxGroup](https://millionrounds.com/fund/boxgroup) *Deploying now* VC firm · United States **773** **$18M** median round **Nov 2026** last seen
- 19 [Menlo Ventures](https://millionrounds.com/fund/menlo-ventures) *Deploying now* VC firm · United States **740** **$37M** median round **Oct 2026** last seen
- 20 [Norwest Venture Partners](https://millionrounds.com/fund/norwest) *Deploying now* VC firm · United States **705** **$25M** median round **Oct 2026** last seen
- 21 [BDC Capital](https://millionrounds.com/fund/bdc-venture-capital) *Deploying now* VC firm · Canada **685** **$6M** median round **Sept 2026** last seen
- 22 [Canaan](https://millionrounds.com/fund/canaan-partners) *Deploying now* VC firm · United States **610** **$20M** median round **Oct 2026** last seen
- 23 [Korea Tech Incubator Program For Startup](https://millionrounds.com/fund/tips-program) *Deploying now* Government · South Korea **597** **$2.1M** median round **Sept 2026** last seen
- 24 [SVB Capital](https://millionrounds.com/fund/svb-capital) *Deploying now* VC firm · United States **564** **$20M** median round **Oct 2026** last seen
- 25 [Venrock](https://millionrounds.com/fund/venrock) *Deploying now* VC firm · United States **560** **$36M** median round **Oct 2026** last seen

**439 more on this list**

All 464 are in the app, with filters for stage, sector and market. A free account shows 10 per search, Pro up to 1,000.

[See the whole list *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fseries-b-biotech-investors)

## The Newest Cheques

Rounds this list's investors joined most recently

- **6** Nov **[Physicl](https://millionrounds.com/company/physicl)** Seed · $10M *With* [U.S. Venture Partners](https://millionrounds.com/fund/u-s-venture-partners-usvp)
- **6** Nov **[Harbinger](https://millionrounds.com/company/harbinger)** Series D+ · $240M *With* [Fidelity](https://millionrounds.com/fund/fidelity)
- **5** Nov **[ArrayPatch](https://millionrounds.com/company/arraypatch)** Seed · $1.8M *With* [Enterprise Ireland](https://millionrounds.com/fund/enterprise-ireland)
- **5** Nov **[T-Therapeutics](https://millionrounds.com/company/t-therapeutics)** Series B · $133M *Led by* [British Business Bank](https://millionrounds.com/fund/national-security-strategic-investment-fund)
- **5** Nov **[Soter Insure](https://millionrounds.com/company/soter-insure)** Series B *With* [Franklin Templeton](https://millionrounds.com/fund/franklin-templeton)
- **5** Nov **[firmly](https://millionrounds.com/company/firmly)** Series A · $15M *With* [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund)

## Stages This Year

5,476 rounds

- Venture **21%**
- Seed **17%**
- Series A **16%**
- Series B **9%**
- Pre-seed **7%**
- Other **29%**

## What They Backed

Sectors, last 12 months

- AI **2,067**
- Biotech **626**
- Healthcare **416**
- Fintech **273**
- Big Data & Analytics **257**
- Energy **198**

## Cheques by Quarter

Led Joined

2,346 Q1 25

2,369 Q2 25

2,639 Q3 25

3,100 Q4 25

2,865 Q1 26

2,668 Q2 26

2,057 Q3 26

602 Q4 26

The last bar is the quarter still running.

## Lists Like This

- [Seed AI investors 2,922](https://millionrounds.com/lists/seed-ai-investors)
- [Series A AI investors 2,490](https://millionrounds.com/lists/series-a-ai-investors)
- [Series B AI investors 1,557](https://millionrounds.com/lists/series-b-ai-investors)
- [Pre-seed AI investors 1,286](https://millionrounds.com/lists/pre-seed-ai-investors)
- [Growth AI investors 1,186](https://millionrounds.com/lists/growth-ai-investors)
- [Series A fintech investors 950](https://millionrounds.com/lists/series-a-fintech-investors)
- [Series C AI investors 930](https://millionrounds.com/lists/series-c-ai-investors)
- [Seed fintech investors 925](https://millionrounds.com/lists/seed-fintech-investors)
- [Series A biotech investors 650](https://millionrounds.com/lists/series-a-biotech-investors)

[All investor lists *→*](https://millionrounds.com/lists)

## Reading for founders in health and biotech

- Silk Road Eileen Ormsby · 2014 3.99 from 548 ratings on Goodreads Health and biotech Company building About the book It was the 'eBay of drugs', a billion dollar empire. Behind it was the FBI's Most Wanted Man, a mysterious crime czar dubbed 'Dread Pirate Roberts'. SILK ROAD lay at the heart of the 'Dark Web' - a parallel internet of porn, guns, assassins and drugs. Lots of drugs. With the… On AmazonListen on Audible
- Where Does It Hurt?: An Entrepreneur's Guide to Fixing Health Care Jonathan Bush · 2014 3.78 from 598 ratings on Goodreads Health and biotech Company building Innovation About the book A bold new remedy for the sprawling and wasteful health care industry Where else but the doctor’s office do you have to fill out a form on a clipboard? Have you noticed that hospital bills are almost unintelligible, except for the absurdly high dollar amount? Why is it that… On AmazonListen on Audible
- The Kelloggs: The Battling Brothers of Battle Creek Howard Markel · 2017 3.87 from 969 ratings on Goodreads Health and biotech Company building About the book "What's more American than Corn Flakes?" --Bing Crosby From the much admired medical historian ("Markel shows just how compelling the medical history can be"--Andrea Barrett) and author of An Anatomy of Addiction ("Absorbing, vivid"--Sherwin Nuland, The New York Times Book… On AmazonListen on Audible
- The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America Allan M. Brandt · 2007 4.10 from 509 ratings on Goodreads Health and biotech Company building About the book The invention of mass marketing led to cigarettes being emblazoned in advertising and film, deeply tied to modern notions of glamour and sex appeal. It is hard to find a photo of Humphrey Bogart or Lauren Bacall without a cigarette. No product has been so heavily promoted or has… On AmazonListen on Audible

More books for founders and investors on the [Reading List](https://millionrounds.com/reading-list?role=founder&industry=health&stage=scaling).

As an Amazon Associate we earn from qualifying purchases.

## Quick answers about series B biotech investors

### Who are the most active series B biotech investors?

By cheques observed, the most active are Y Combinator, 500 Global, Sequoia Capital, National Science Foundation and Andreessen Horowitz.

### How many series B biotech investors are there?

464 are on record. 92% made an investment in the last 12 months and 60% have led a round.

### Which stages do series B biotech investors back?

Of the rounds with a named stage in the last 12 months, mostly Seed (24%) and Series A (24%).

### How big are the rounds series B biotech investors join?

The typical (median) round among the leading investors here is $20M.

### Which sectors do series B biotech investors back most?

In the last 12 months, mostly AI, Biotech and Healthcare.

### Which series B biotech investors lead the most rounds?

Andreessen Horowitz (114 led), General Catalyst (97 led) and Sequoia Capital (91 led).

### Where are series B biotech investors based?

Most of the leading investors here are based in the United States (20 of the top 25); the rest in France and the United Kingdom.

### What have series B biotech investors invested in recently?

Recent rounds include Physicl (Seed, Nov 2026, with U.S. Venture Partners), Harbinger (Series D+, Nov 2026, with Fidelity) and ArrayPatch (Seed, Nov 2026, with Enterprise Ireland).

Built from the rounds we watched, refreshed every night. [How we count](https://millionrounds.com/methodology) · [Report a correction](https://millionrounds.com/corrections)