# Pre-seed biotech investors (2026 list)

> 139 pre-seed biotech investors, 92% active in the last 12 months. Led by Y Combinator, Techstars, National Science Foundation. Ranked by what they funded.

Source: https://millionrounds.com/lists/pre-seed-biotech-investors (Millionrounds; every figure on the page links to its filing or article)

[Investor Lists](https://millionrounds.com/lists)

# Pre-seed biotech investors

Updated 7 November 2026

Firms we have watched take part in a pre-seed round raised by a biotech company in the last two years. Both the stage and the sector are what they did, not what their website says.

[See all 139 *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fpre-seed-biotech-investors)The top 25

**139** investors on the list *+2* this week

**3,598** cheques in 12 months *-21%* against the market

**$3M** median round they joined *-62%* against the market median

**92%** wrote a cheque in 12 months

**49%** have led a round

## The Top 25

Ordered by cheques observed, never by anything anyone paid for

Deploying now (25)

- 1 [Y Combinator](https://millionrounds.com/fund/y-combinator) *Deploying now* Accelerator · United States **6,412** **$3M** median round **Oct 2026** last seen
- 2 [Techstars](https://millionrounds.com/fund/techstars) *Deploying now* VC firm · United States **2,989** **$1.2M** median round **Nov 2026** last seen
- 3 [National Science Foundation](https://millionrounds.com/fund/nsf-small-business-innovation-research-small-business-techno) *Deploying now* Government · United States **1,869** **$926K** median round **Sept 2026** last seen
- 4 [Bpifrance](https://millionrounds.com/fund/bpifrance) *Deploying now* Government · France **1,151** **$4.5M** median round **Oct 2026** last seen
- 5 [MassChallenge](https://millionrounds.com/fund/masschallenge) *Deploying now* Accelerator · United States **984** **$1.8M** median round **Sept 2026** last seen
- 6 [SOSV](https://millionrounds.com/fund/sosv) *Deploying now* VC firm · United States **951** **$2.5M** median round **Nov 2026** last seen
- 7 [Innovate UK](https://millionrounds.com/fund/innovate-uk) *Deploying now* VC firm · United Kingdom **704** **$1.2M** median round **Oct 2026** last seen
- 8 [Pioneer Fund](https://millionrounds.com/fund/pioneer-fund-2) *Deploying now* Private equity · United States **551** **$2.9M** median round **Nov 2026** last seen
- 9 [Seedcamp](https://millionrounds.com/fund/seedcamp) *Deploying now* VC firm · United Kingdom **519** **$5M** median round **Nov 2026** last seen
- 10 [SFC Capital](https://millionrounds.com/fund/sfc-capital) *Deploying now* Angel network · United Kingdom **379** **$431K** median round **Nov 2026** last seen
- 11 [Draper Associates](https://millionrounds.com/fund/draper-associates) *Deploying now* VC firm · United States **370** **$6M** median round **Nov 2026** last seen
- 12 [Neo](https://millionrounds.com/fund/neo) *Deploying now* Accelerator · United States **364** **$5.5M** median round **Nov 2026** last seen
- 13 [FundersClub](https://millionrounds.com/fund/fundersclub) *Deploying now* VC firm · United States **348** **$4.8M** median round **Jul 2026** last seen
- 14 [K Fund](https://millionrounds.com/fund/kfund) *Deploying now* VC firm · Spain **340** **$3M** median round **Oct 2026** last seen
- 15 [Entrepreneur First](https://millionrounds.com/fund/entrepreneurs-first) *Deploying now* Accelerator · United Kingdom **332** **$3.6M** median round **Oct 2026** last seen
- 16 [Venture Kick](https://millionrounds.com/fund/venture-kick) *Deploying now* Accelerator · Switzerland **329** **$2.1M** median round **Nov 2026** last seen
- 17 [Almi Invest](https://millionrounds.com/fund/almi-invest) *Deploying now* VC firm · Sweden **328** **$1.1M** median round **Nov 2026** last seen
- 18 [Legend Capital](https://millionrounds.com/fund/legend-capital) *Deploying now* VC firm · China **288** **$26M** median round **Oct 2026** last seen
- 19 [Hustle Fund](https://millionrounds.com/fund/hustle-fund) *Deploying now* VC firm · United States **280** **$3M** median round **Oct 2026** last seen
- 20 [LocalGlobe](https://millionrounds.com/fund/localglobe) *Deploying now* VC firm · United Kingdom **269** **$12M** median round **Oct 2026** last seen
- 21 [Precursor Ventures](https://millionrounds.com/fund/precursor-ventures) *Deploying now* VC firm · United States **261** **$4M** median round **Oct 2026** last seen
- 22 [Scottish Enterprise](https://millionrounds.com/fund/scottish-enterprise) *Deploying now* Government · United Kingdom **256** **$2.1M** median round **Nov 2026** last seen
- 23 [Callaghan Innovation](https://millionrounds.com/fund/callaghan-innovation) *Deploying now* Investment firm · New Zealand **254** **$109K** median round **Sept 2026** last seen
- 24 [CDP Venture Capital](https://millionrounds.com/fund/cdp-venture-capital) *Deploying now* VC firm · Italy **227** **$3.9M** median round **Oct 2026** last seen
- 25 [Sting](https://millionrounds.com/fund/sting) *Deploying now* VC firm · United States **219** **$1.5M** median round **Sept 2026** last seen

**114 more on this list**

All 139 are in the app, with filters for stage, sector and market. A free account shows 10 per search, Pro up to 1,000.

[See the whole list *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fpre-seed-biotech-investors)

## The Newest Cheques

Rounds this list's investors joined most recently

- **7** Nov **[LionBio Therapeutics](https://millionrounds.com/company/lionbio-therapeutics)** Pre-seed · $6M *With* [South Park Commons](https://millionrounds.com/fund/south-park-commons)
- **5** Nov **[Nyquis](https://millionrounds.com/company/nyquis)** Seed · $6.3M *Led by* [South Park Commons](https://millionrounds.com/fund/south-park-commons)
- **5** Nov **[Granit](https://millionrounds.com/company/granit)** Seed · $6M *Led by* [Seedcamp](https://millionrounds.com/fund/seedcamp)
- **5** Nov **[Venomics AI](https://millionrounds.com/company/venomics-ai)** Pre-seed · $2.7M *Led by* [South Park Commons](https://millionrounds.com/fund/south-park-commons)
- **5** Nov **[Nayara](https://millionrounds.com/company/nayara)** Pre-seed · $522K *Led by* [SFC Capital](https://millionrounds.com/fund/sfc-capital)
- **5** Nov **[Quint Computing](https://millionrounds.com/company/quint-computing)** Series A · $10M *With* [Nucleus Capital](https://millionrounds.com/fund/nucleus-capital)

## Stages This Year

3,016 rounds

- Seed **23%**
- Venture **23%**
- Pre-seed **17%**
- Series A **15%**
- Grant **6%**
- Other **17%**

## What They Backed

Sectors, last 12 months

- AI **1,149**
- Biotech **271**
- Healthcare **215**
- Big Data & Analytics **137**
- Fintech **122**
- Energy **110**

## Cheques by Quarter

Led Joined

1,204 Q1 25

1,119 Q2 25

1,313 Q3 25

1,262 Q4 25

1,155 Q1 26

974 Q2 26

807 Q3 26

162 Q4 26

The last bar is the quarter still running.

## Lists Like This

- [Seed AI investors 2,922](https://millionrounds.com/lists/seed-ai-investors)
- [Series A AI investors 2,490](https://millionrounds.com/lists/series-a-ai-investors)
- [Series B AI investors 1,557](https://millionrounds.com/lists/series-b-ai-investors)
- [Pre-seed AI investors 1,286](https://millionrounds.com/lists/pre-seed-ai-investors)
- [Growth AI investors 1,186](https://millionrounds.com/lists/growth-ai-investors)
- [Series A fintech investors 950](https://millionrounds.com/lists/series-a-fintech-investors)
- [Series C AI investors 930](https://millionrounds.com/lists/series-c-ai-investors)
- [Seed fintech investors 925](https://millionrounds.com/lists/seed-fintech-investors)
- [Series A biotech investors 650](https://millionrounds.com/lists/series-a-biotech-investors)

[All investor lists *→*](https://millionrounds.com/lists)

## Reading for founders in health and biotech

- The Innovator's Prescription: A Disruptive Solution for Health Care Clayton M. Christensen · 2008 4.21 from 1,158 ratings on Goodreads Health and biotech Innovation Moats and competition About the book A groundbreaking prescription for health care reform--from a legendary leader in innovation... Our health care system is in critical condition. Each year, fewer Americans can afford it, fewer businesses can provide it, and fewer government programs can promise it for future… On AmazonListen on Audible
- Where Does It Hurt?: An Entrepreneur's Guide to Fixing Health Care Jonathan Bush · 2014 3.78 from 598 ratings on Goodreads Health and biotech Company building Innovation About the book A bold new remedy for the sprawling and wasteful health care industry Where else but the doctor’s office do you have to fill out a form on a clipboard? Have you noticed that hospital bills are almost unintelligible, except for the absurdly high dollar amount? Why is it that… On AmazonListen on Audible
- Ashes to Ashes: America's Hundred-Year Cigarette War, the Public Health, and the Unabashed Triumph of Philip Morris Richard Kluger · 1997 3.94 from 306 ratings on Goodreads Health and biotech Company building About the book Ashes to Ashes is a monumental history of the American tobacco industry’s ironic success in developing the cigarette, modern society’s most widespread instrument of self-destruction, into the nation’s most profitable consumer product. Starting with its energized, work-obsessed… On AmazonListen on Audible
- The Kelloggs: The Battling Brothers of Battle Creek Howard Markel · 2017 3.87 from 969 ratings on Goodreads Health and biotech Company building About the book "What's more American than Corn Flakes?" --Bing Crosby From the much admired medical historian ("Markel shows just how compelling the medical history can be"--Andrea Barrett) and author of An Anatomy of Addiction ("Absorbing, vivid"--Sherwin Nuland, The New York Times Book… On AmazonListen on Audible

More books for founders and investors on the [Reading List](https://millionrounds.com/reading-list?role=founder&industry=health&stage=idea).

As an Amazon Associate we earn from qualifying purchases.

## Quick answers about pre-seed biotech investors

### Who are the most active pre-seed biotech investors?

By cheques observed, the most active are Y Combinator, Techstars, National Science Foundation, Bpifrance and MassChallenge.

### How many pre-seed biotech investors are there?

139 are on record. 92% made an investment in the last 12 months and 49% have led a round.

### Which stages do pre-seed biotech investors back?

Of the rounds with a named stage in the last 12 months, mostly Seed (31%) and Pre-seed (23%).

### How big are the rounds pre-seed biotech investors join?

The typical (median) round among the leading investors here is $3M.

### Which sectors do pre-seed biotech investors back most?

In the last 12 months, mostly AI, Biotech and Healthcare.

### Which pre-seed biotech investors lead the most rounds?

Y Combinator (11 led), Bpifrance (11 led) and Seedcamp (6 led).

### Where are pre-seed biotech investors based?

Among the most active, most are based in the United States (12), the United Kingdom (6) and France (1).

### What have pre-seed biotech investors invested in recently?

Recent rounds include LionBio Therapeutics (Pre-seed, Nov 2026, with South Park Commons), Nyquis (Seed, Nov 2026, with South Park Commons) and Granit (Seed, Nov 2026, with Seedcamp).

Built from the rounds we watched, refreshed every night. [How we count](https://millionrounds.com/methodology) · [Report a correction](https://millionrounds.com/corrections)