# Biotech lead investors (2026 list)

> 348 biotech lead investors, 91% active in the last 12 months. Led by Sequoia Capital, Andreessen Horowitz, New Enterprise Associates.

Source: https://millionrounds.com/lists/biotech-lead-investors (Millionrounds; every figure on the page links to its filing or article)

[Investor Lists](https://millionrounds.com/lists)

# Biotech lead investors

Updated 7 November 2026

Firms we have watched lead a round raised by a biotech company in the last two years. Leading is rarer than taking part, and it is the role a founder most needs filled.

[See all 348 *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fbiotech-lead-investors)The top 25

**348** investors on the list *+9* this week

**5,178** cheques in 12 months *+9%* against the market

**$26M** median round they joined *+225%* against the market median

**91%** wrote a cheque in 12 months

**100%** have led a round

## The Top 25

Ordered by cheques observed, never by anything anyone paid for

Deploying now (25)

- 1 [Sequoia Capital](https://millionrounds.com/fund/sequoia-capital) *Deploying now* VC firm · United States **2,099** **$35M** median round **Nov 2026** last seen
- 2 [Andreessen Horowitz](https://millionrounds.com/fund/andreessen-horowitz) *Deploying now* VC firm · United States **1,661** **$27M** median round **Nov 2026** last seen
- 3 [New Enterprise Associates](https://millionrounds.com/fund/new-enterprise-associates) *Deploying now* VC firm · United States **1,610** **$34M** median round **Oct 2026** last seen
- 4 [General Catalyst](https://millionrounds.com/fund/general-catalyst) *Deploying now* VC firm · United States **1,387** **$27M** median round **Nov 2026** last seen
- 5 [Lightspeed Venture Partners](https://millionrounds.com/fund/lightspeed-venture-partners) *Deploying now* VC firm · United States **1,341** **$35M** median round **Nov 2026** last seen
- 6 [Bpifrance](https://millionrounds.com/fund/bpifrance) *Deploying now* Government · France **1,151** **$4.5M** median round **Oct 2026** last seen
- 7 [Khosla Ventures](https://millionrounds.com/fund/khosla-ventures) *Deploying now* VC firm · United States **1,128** **$26M** median round **Nov 2026** last seen
- 8 [Founders Fund](https://millionrounds.com/fund/founders-fund) *Deploying now* VC firm · United States **1,122** **$15M** median round **Oct 2026** last seen
- 9 [Bessemer Venture Partners](https://millionrounds.com/fund/bessemer-venture-partners) *Deploying now* VC firm · United States **1,038** **$30M** median round **Nov 2026** last seen
- 10 [Google Ventures](https://millionrounds.com/fund/gv) *Deploying now* Corporate VC · United States **884** **$38M** median round **Oct 2026** last seen
- 11 [EIC Accelerator](https://millionrounds.com/fund/eic-accelerator) *Deploying now* Government · European Union **875** **$4.3M** median round **Oct 2026** last seen
- 12 [First Round Capital](https://millionrounds.com/fund/first-round-capital) *Deploying now* VC firm · United States **807** **$18M** median round **Oct 2026** last seen
- 13 [Insight Partners](https://millionrounds.com/fund/insight-venture-partners) *Deploying now* VC firm · United States **765** **$40M** median round **Oct 2026** last seen
- 14 [Redpoint](https://millionrounds.com/fund/redpoint) *Deploying now* VC firm · United States **742** **$32M** median round **Nov 2026** last seen
- 15 [Menlo Ventures](https://millionrounds.com/fund/menlo-ventures) *Deploying now* VC firm · United States **740** **$37M** median round **Oct 2026** last seen
- 16 [Norwest Venture Partners](https://millionrounds.com/fund/norwest) *Deploying now* VC firm · United States **705** **$25M** median round **Oct 2026** last seen
- 17 [Qiming Venture Partners](https://millionrounds.com/fund/qiming-venture-partners) *Deploying now* VC firm · Hong Kong SAR China **526** **$25M** median round **Oct 2026** last seen
- 18 [IDG Capital](https://millionrounds.com/fund/idg-capital) *Deploying now* Private equity · China **504** **$25M** median round **Oct 2026** last seen
- 19 [HSG](https://millionrounds.com/fund/hsg) *Deploying now* VC firm · Hong Kong SAR China **498** **$31M** median round **Oct 2026** last seen
- 20 [8VC](https://millionrounds.com/fund/8vc) *Deploying now* VC firm · United States **497** **$23M** median round **Oct 2026** last seen
- 21 [Atlas Venture](https://millionrounds.com/fund/atlas-venture) *Deploying now* VC firm · United States **492** **$43M** median round **Oct 2026** last seen
- 22 [Polaris Partners](https://millionrounds.com/fund/polaris-partners) *Deploying now* VC firm · United States **490** **$36M** median round **Oct 2026** last seen
- 23 [Spark Capital](https://millionrounds.com/fund/spark-capital) *Deploying now* VC firm · United States **471** **$40M** median round **Oct 2026** last seen
- 24 [OrbiMed](https://millionrounds.com/fund/orbimed) *Deploying now* Private equity · United States **447** **$71M** median round **Oct 2026** last seen
- 25 [Lux Capital](https://millionrounds.com/fund/lux-capital) *Deploying now* VC firm · United States **445** **$30M** median round **Nov 2026** last seen

**323 more on this list**

All 348 are in the app, with filters for stage, sector and market. A free account shows 10 per search, Pro up to 1,000.

[See the whole list *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fbiotech-lead-investors)

## The Newest Cheques

Rounds this list's investors joined most recently

- **7** Nov **[LionBio Therapeutics](https://millionrounds.com/company/lionbio-therapeutics)** Pre-seed · $6M *With* [South Park Commons](https://millionrounds.com/fund/south-park-commons)
- **6** Nov **[MucoLife Therapeutics](https://millionrounds.com/company/mucolife-therapeutics)** Grant · $102K *Led by* [Vinnova](https://millionrounds.com/fund/vinnova)
- **6** Nov **[Banesco Banco Múltiple](https://millionrounds.com/company/banesco-banco-multiple)** Debt · $25M *Led by* [PROPARCO](https://millionrounds.com/fund/proparco)
- **6** Nov **[Fathom Therapeutics](https://millionrounds.com/company/fathom-therapeutics)** Round *With* [Sutter Hill Ventures](https://millionrounds.com/fund/sutter-hill-ventures)
- **6** Nov **[Humble Robotics](https://millionrounds.com/company/humble-robotics)** Series A · $51M *Led by* [Obvious Ventures](https://millionrounds.com/fund/obvious-ventures)
- **5** Nov **[ArrayPatch](https://millionrounds.com/company/arraypatch)** Seed · $1.8M *Led by* [DeepIE Ventures](https://millionrounds.com/fund/deepie-ventures)

## Stages This Year

3,313 rounds

- Series A **20%**
- Seed **17%**
- Venture **16%**
- Series B **11%**
- Other **9%**
- Other **28%**

## What They Backed

Sectors, last 12 months

- AI **1,311**
- Biotech **533**
- Healthcare **315**
- Fintech **180**
- Big Data & Analytics **164**
- Robotics **144**

## Cheques by Quarter

Led Joined

1,117 Q1 25

1,189 Q2 25

1,368 Q3 25

1,560 Q4 25

1,519 Q1 26

1,418 Q2 26

1,183 Q3 26

444 Q4 26

The last bar is the quarter still running.

## Lists Like This

- [AI lead investors 1,723](https://millionrounds.com/lists/ai-lead-investors)
- [Lead investors in United States 1,370](https://millionrounds.com/lists/lead-investors-in-united-states)
- [Seed lead investors 1,091](https://millionrounds.com/lists/seed-lead-investors)
- [Series A lead investors 920](https://millionrounds.com/lists/series-a-lead-investors)
- [Fintech lead investors 763](https://millionrounds.com/lists/fintech-lead-investors)
- [Series B lead investors 579](https://millionrounds.com/lists/series-b-lead-investors)
- [Growth lead investors 555](https://millionrounds.com/lists/growth-lead-investors)
- [Robotics lead investors 397](https://millionrounds.com/lists/robotics-lead-investors)
- [Pre-seed lead investors 396](https://millionrounds.com/lists/pre-seed-lead-investors)

[All investor lists *→*](https://millionrounds.com/lists)

## Quick answers about biotech lead investors

### Who are the most active biotech lead investors?

By cheques observed, the most active are Sequoia Capital, Andreessen Horowitz, New Enterprise Associates, General Catalyst and Lightspeed Venture Partners.

### How many biotech lead investors are there?

348 are on record. 91% made an investment in the last 12 months and 100% have led a round.

### Which stages do biotech lead investors back?

Of the rounds with a named stage in the last 12 months, mostly Series A (28%) and Seed (23%).

### How big are the rounds biotech lead investors join?

The typical (median) round among the leading investors here is $30M.

### Which sectors do biotech lead investors back most?

In the last 12 months, mostly AI, Biotech and Healthcare.

### Which biotech lead investors lead the most rounds?

Andreessen Horowitz (114 led), General Catalyst (97 led) and Sequoia Capital (91 led).

### Where are biotech lead investors based?

Most of the leading investors here are based in the United States (20 of the top 25); the rest in Hong Kong SAR China and France.

### What have biotech lead investors invested in recently?

Recent rounds include LionBio Therapeutics (Pre-seed, Nov 2026, with South Park Commons), MucoLife Therapeutics (Grant, Nov 2026, with Vinnova) and Banesco Banco Múltiple (Debt, Nov 2026, with PROPARCO).

Built from the rounds we watched, refreshed every night. [How we count](https://millionrounds.com/methodology) · [Report a correction](https://millionrounds.com/corrections)
