# Biotech investors based in Chicago (2026 list)

> 20 biotech investors based in Chicago, 95% active in the last 12 months. Led by Alumni Ventures, ARCH Venture Partners, Valor Equity Partners.

Source: https://millionrounds.com/lists/biotech-investors-based-in-chicago (Millionrounds; every figure on the page links to its filing or article)

[Investor Lists](https://millionrounds.com/lists)

# Biotech investors based in Chicago

Updated 7 November 2026

Firms with an address in Chicago that we have watched back a biotech company in the last two years.

[See all 20 *→*](https://millionrounds.com/login?join=1&next=%2Fapp%2Finvestor-lists%2Fbiotech-investors-based-in-chicago)The top 20

**20** investors on the list *+1* this week

**518** cheques in 12 months *-1%* against the market

**$39M** median round they joined *+383%* against the market median

**95%** wrote a cheque in 12 months

**70%** have led a round

## The Top 20

Ordered by cheques observed, never by anything anyone paid for

Deploying now (19)

- 1 [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund) *Deploying now* VC firm · United States **1,598** **$12M** median round **Nov 2026** last seen
- 2 [ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) *Deploying now* VC firm · United States **337** **$74M** median round **Oct 2026** last seen
- 3 [Valor Equity Partners](https://millionrounds.com/fund/valor-equity-partners) *Deploying now* VC firm · United States **261** **$50M** median round **Nov 2026** last seen
- 4 [Lightbank](https://millionrounds.com/fund/lightbank) *Deploying now* VC firm · United States **206** **$5.5M** median round **Oct 2026** last seen
- 5 [Adams Street Partners](https://millionrounds.com/fund/adams-street-partners) *Deploying now* VC firm · United States **188** **$70M** median round **Oct 2026** last seen
- 6 [S2G Investments](https://millionrounds.com/fund/s2g-investments) *Deploying now* Growth equity · United States **102** **$16M** median round **Oct 2026** last seen
- 7 [Blue Owl](https://millionrounds.com/fund/blue-owl) *Deploying now* Asset manager · United States **59** **$189M** median round **Oct 2026** last seen
- 8 [The Blue Venture Fund](https://millionrounds.com/fund/bluecross-blueshield-venture-partners) *Deploying now* Corporate VC · United States **44** **$23M** median round **Aug 2026** last seen
- 9 [Evergreen Climate Innovations](https://millionrounds.com/fund/evergreen-climate-innovations) *Deploying now* VC firm · United States **33** **$2.4M** median round **Sept 2026** last seen
- 10 [Peak 6](https://millionrounds.com/fund/peak-6) *Deploying now* Corporate VC · United States **12** **$20M** median round **Aug 2026** last seen
- 11 [DRW](https://millionrounds.com/fund/drw) *Deploying now* VC firm · United States **9** **$22M** median round **Oct 2026** last seen
- 12 [Balyasny Asset Management L.p.](https://millionrounds.com/fund/balyasny-asset-management-2) *Deploying now* Private equity · United States **8** **$244M** median round **Oct 2026** last seen
- 13 [BDT & MSD Partners](https://millionrounds.com/fund/bdt-and-msd-partners) *Deploying now* Investment bank · United States **7** **$500M** median round **Jul 2026** last seen
- 14 [M&G Investments](https://millionrounds.com/fund/m-and-g-investments) *Deploying now* Private equity · United Kingdom **6** **$113M** median round **Nov 2026** last seen
- 15 [OMX Ventures](https://millionrounds.com/fund/omx-ventures) *Deploying now* VC firm · United States **4** **$27M** median round **Apr 2026** last seen
- 16 [TWG Global](https://millionrounds.com/fund/twg-global) *Deploying now* Growth equity · United States **4** **$425M** median round **Apr 2026** last seen
- 17 [Driehaus Capital Management](https://millionrounds.com/fund/driehaus-capital-management) *Deploying now* Private equity · United States **3** **$55M** median round **Mar 2026** last seen
- 18 [Germin8 Ventures](https://millionrounds.com/fund/germin8-ventures) quiet VC firm · United States **3** **$27M** median round **Jun 2025** last seen
- 19 [Earth Foundry](https://millionrounds.com/fund/earth-foundry) *Deploying now* VC firm · United States **1** **$12M** median round **Oct 2026** last seen
- 20 [Pathway Bioventures](https://millionrounds.com/fund/pathway-bioventures) *Deploying now* VC firm · United States **1** **$83M** median round **May 2026** last seen

## The Newest Cheques

Rounds this list's investors joined most recently

- **5** Nov **[firmly](https://millionrounds.com/company/firmly)** Series A · $15M *With* [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund)
- **5** Nov **[RadianX](https://millionrounds.com/company/radianx)** Seed · $9M *With* [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund)
- **5** Nov **[Zipline](https://millionrounds.com/company/zipline)** Growth · $1.5B *With* [Valor Equity Partners](https://millionrounds.com/fund/valor-equity-partners)
- **4** Nov **[bit.bio](https://millionrounds.com/company/bit-bio)** Series D+ · $25M *With* [M&G Investments](https://millionrounds.com/fund/m-and-g-investments)
- **2** Nov **[Larridin](https://millionrounds.com/company/larridin)** Series A · $30M *With* [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund)
- **29** Oct **[Wrapped Health](https://millionrounds.com/company/wrapped-health)** Pre-seed · $2.1M *Led by* [Lightbank](https://millionrounds.com/fund/lightbank)

## Stages This Year

498 rounds

- Venture **19%**
- Series A **17%**
- Seed **13%**
- Series B **13%**
- Series C **8%**
- Other **30%**

## What They Backed

Sectors, last 12 months

- AI **186**
- Biotech **56**
- Healthcare **33**
- Energy **31**
- Fintech **29**
- Big Data & Analytics **27**

## Cheques by Quarter

Led Joined

147 Q1 25

135 Q2 25

136 Q3 25

158 Q4 25

176 Q1 26

123 Q2 26

133 Q3 26

27 Q4 26

The last bar is the quarter still running.

## Lists Like This

- [AI investors based in San Francisco 353](https://millionrounds.com/lists/ai-investors-based-in-san-francisco)
- [AI investors based in New York 345](https://millionrounds.com/lists/ai-investors-based-in-new-york)
- [Seed investors based in San Francisco 273](https://millionrounds.com/lists/seed-investors-based-in-san-francisco)
- [Series A investors based in San Francisco 266](https://millionrounds.com/lists/series-a-investors-based-in-san-francisco)
- [Series A investors based in New York 255](https://millionrounds.com/lists/series-a-investors-based-in-new-york)
- [Seed investors based in New York 227](https://millionrounds.com/lists/seed-investors-based-in-new-york)
- [AI investors based in London 223](https://millionrounds.com/lists/ai-investors-based-in-london)
- [Series B investors based in New York 198](https://millionrounds.com/lists/series-b-investors-based-in-new-york)
- [Fintech investors based in New York 197](https://millionrounds.com/lists/fintech-investors-based-in-new-york)

[All investor lists *→*](https://millionrounds.com/lists)

## Quick answers about biotech investors based in Chicago

### Who are the most active biotech investors based in Chicago?

By cheques observed, the most active are Alumni Ventures, ARCH Venture Partners, Valor Equity Partners, Lightbank and Adams Street Partners.

### How many biotech investors based in Chicago are there?

20 are on record. 95% made an investment in the last 12 months and 70% have led a round.

### Which stages do biotech investors based in Chicago back?

Of the rounds with a named stage in the last 12 months, mostly Series A (24%) and Seed (19%).

### How big are the rounds biotech investors based in Chicago join?

The typical (median) round among the leading investors here is $50M.

### Which sectors do biotech investors based in Chicago back most?

In the last 12 months, mostly AI, Biotech and Healthcare.

### Which biotech investors based in Chicago lead the most rounds?

Valor Equity Partners (21 led), ARCH Venture Partners (12 led) and TWG Global (4 led).

### What have biotech investors based in Chicago invested in recently?

Recent rounds include firmly (Series A, Nov 2026, with Alumni Ventures), RadianX (Seed, Nov 2026, with Alumni Ventures) and Zipline (Growth, Nov 2026, with Valor Equity Partners).

### How is this list of biotech investors based in Chicago ranked?

By cheques observed, from the rounds and filings we watched, and never by anything anyone paid for. It is rebuilt every night.

Built from the rounds we watched, refreshed every night. [How we count](https://millionrounds.com/methodology) · [Report a correction](https://millionrounds.com/corrections)
