# Third Rock Ventures: portfolio, investments and team

> Third Rock Ventures is a vc firm based in United States. 84 investments on record, latest Jul 2019. Portfolio, stages, co-investors and team.

Source: https://millionrounds.com/fund/third-rock-ventures (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Third Rock Ventures

Filed with the SEC to raise a fund in Jun 2026, closing $1,105M. Last cheque observed Jul 2019.

Email

Quiet New fund $1.1B, Jun 2026 VC firm

Pre-seed Biotech Pharmaceuticals Bio

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Cheques on record

**0%** of best year **0** **cheques in 12 months**, 84 on record

Since the last cheque **2671** days **00** hrs **00** min **00** sec

Median round **$56M** Cheque size, as they say **$5.0M – $100M** Rounds led **1 of 84** Sole investor **15 rounds** Exits **5 from the portfolio** Mostly in **United States, 95%**

Pitch Third Rock Ventures

## Third Rock Ventures highlights

- 01 84 rounds on record
- 02 Mostly Series A and Series B: 81% of its rounds
- 03 Sole investor in 15 rounds, median $47M
- 04 5 exits from the portfolio

## What they do

> Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine From their own website

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** $5.0M – $100M as they say
- **Stages:** Pre-seed
- **Sectors:** Biotech Pharmaceuticals Bio
- **Based in:** Boston, United States
- **Cold pitches:** Not accepted

## The record

Every round we can evidence, newest first **84 appearances**

- **2019** 3 rounds
- **Jul** **[Revolution Medicines](https://millionrounds.com/company/revolution-medicines)** Series C · US · FinSMEs **$100M** With 9 others
- **May** **[Thrive](https://millionrounds.com/company/thrive)** Series A · US · FinSMEs **$110M** *Led*
- **Apr** **[Public food doctor](https://millionrounds.com/company/public-food-doctor)** CN **$15M** With 3 others
- **2018** 6 rounds
- **Aug** **[Ambys](https://millionrounds.com/company/ambys)** Series A · US · FinSMEs **$140M** With 1 other
- **Jun** **[Decibel Therapeutics](https://millionrounds.com/company/decibel-therapeutics)** Series C · US · FinSMEs **$55M** With 8 others
- **May** **[Casma](https://millionrounds.com/company/casma)** Series A · US · FinSMEs **$59M** Sole investor
- **Apr** **[Cedilla Therapeutics](https://millionrounds.com/company/cedilla-therapeutics)** Series A · US · FinSMEs **$56M** Sole investor
- **Apr** **[Constellation](https://millionrounds.com/company/constellation)** US · FinSMEs **$100M** With 12 others
- **Mar** **[Rheos Medicies](https://millionrounds.com/company/rheos-medicies)** Series A · US · FinSMEs **$60M** Sole investor
- **2017** 5 rounds
- **Dec** **[Relay](https://millionrounds.com/company/relay)** Series B · US · FinSMEs **$63M** With 5 others
- **Oct** **[PanOptica](https://millionrounds.com/company/panoptica)** Series B · US · FinSMEs **$11M** With 1 other
- **May** **[Magenta Therpeutics](https://millionrounds.com/company/magenta-therpeutics)** Series B · US · FinSMEs **$50M** With 5 others
- **Mar** **[Tango Therapeutics](https://millionrounds.com/company/tango-therapeutics)** Series A · US · FinSMEs **$55M** Sole investor
- **Feb** **[Rhythm](https://millionrounds.com/company/rhythm)** US · FinSMEs **$41M** With 6 others
- **2016** 4 rounds
- **Dec** **[Goldfinch Bio](https://millionrounds.com/company/goldfinch-bio)** Series A · US · FinSMEs **$55M** Sole investor
- **Nov** **[Magenta Therapeutics](https://millionrounds.com/company/magenta-therapeutics)** Series A · US · FinSMEs **$49M** With 1 other
- **Sept** **[Relay Therapeutics](https://millionrounds.com/company/relay-therapeutics)** Series A · US · FinSMEs **$57M** Sole investor
- **Jul** **[Fulcrum Therapeutics](https://millionrounds.com/company/fulcrum-therapeutics)** Series A · US · FinSMEs **$55M** Sole investor
- **2015** 6 rounds
- **Oct** **[Decibel Therapeutics](https://millionrounds.com/company/decibel-therapeutics)** Series A **$52M** With 2 others
- **Oct** **[Neon Therapeutics](https://millionrounds.com/company/neon-therapeutics)** Series A · US **$55M** With 2 others
- **Aug** **[Rhythm Pharmaceuticals](https://millionrounds.com/company/rhythm-pharmaceuticals)** Series A · US **$40M** With 7 others
- **Aug** **[Editas Medicine](https://millionrounds.com/company/editas-medicine)** Series B · US **$120M** With 14 others
- **Feb** **[Revolution Medicines](https://millionrounds.com/company/revolution-medicines)** Series A · US **$45M** Sole investor
- **Jan** **[CytomX Therapeutics](https://millionrounds.com/company/cytomx-therapeutics)** Series C · US **$20M** With 3 others
- **2014** 10 rounds
- **Dec** **[Allena Pharmaceuticals](https://millionrounds.com/company/allena-pharmaceuticals)** Series B · US **$25M** With 4 others
- **Jul** **[Corvia Medical](https://millionrounds.com/company/corvia-medical)** Series D · US **$34M** With 3 others
- **May** **[Nurix](https://millionrounds.com/company/nurix)** Series B · US **$25M** With 1 other
- **Apr** **[Kala Pharmaceuticals](https://millionrounds.com/company/kala-pharmaceuticals)** Series B · US **$23M** With 5 others
- **Apr** **[PanOptica](https://millionrounds.com/company/panoptica)** Series B · US **$45M** With 2 others
- **Mar** **[NinePoint Medical](https://millionrounds.com/company/ninepoint-medical)** Series B · US **$34M** With 2 others
- **Mar** **[SAGE Therapeutics](https://millionrounds.com/company/sage-therapeutics)** Series C · GB **$38M** With 4 others
- **Feb** **[Voyager Therapeutics](https://millionrounds.com/company/voyager-therapeutics)** Series A · US **$45M** Sole investor
- **Jan** **[Igenica](https://millionrounds.com/company/igenica)** Series C · US **$14M** With 3 others
- **Jan** **[Blueprint Medicines](https://millionrounds.com/company/blueprint-medicines)** Series B · US **$25M** With 5 others
- **2013** 7 rounds
- **Nov** **[Editas Medicine](https://millionrounds.com/company/editas-medicine)** Series A · US · finsmes.com **$43M** With 3 others
- **Oct** **[SAGE Therapeutics](https://millionrounds.com/company/sage-therapeutics)** Series B · US · 4-traders.com **$20M** With 1 other
- **Jul** **[Alcresta](https://millionrounds.com/company/alcresta)** Series B · US · finsmes.com **$10M** With 2 others
- **Mar** **[TARIS Biomedical](https://millionrounds.com/company/taris-biomedical)** Growth · US · sec.gov **$14M** With 3 others
- **Mar** **[Corvia Medical](https://millionrounds.com/company/corvia-medical)** Series A · US · sec.gov **$11M** With 2 others
- **Feb** **[Kala Pharmaceuticals](https://millionrounds.com/company/kala-pharmaceuticals)** Series A · US · finsmes.com **$12M** With 3 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **15 named**

AC **Abbie Celniker** Manager of the GPLLC. i Filing they signed

AB **Alexis Borisy** Manager of the GPLLC. i Filing they signed

AC **Alison Connors** Chief Financial Officer i Form ADV

AV **Andrea van Elsas** Manager of the GPLLC. i Filing they signed

CP **Cary Pfeffer** Manager of the GPLLC. i Filing they signed

CM **Craig Muir** Manager of the GPLLC. i Filing they signed

DK **David Kaufman** Manager of the GPLLC. i Filing they signed

JK **Jeffrey K Tong** Manager of the GPLLC. i Filing they signed

JR **Jigar Raythatha** Manager of the GPLLC. i Filing they signed

KM **Kevin Michael Gillis** Chief Operating Officer i Form ADV

KS **Kevin Starr** Manager of the General Partner's general partner. i Filing they signed

ML **Mark Levin** Manager of the General Partner's general partner. i Filing they signed

NE **Neil Exter** Manager of the GPLLC. i Filing they signed

RM **Reid M Huber** Manager of the GPLLC. i Filing they signed

RI **Robert Ira Tepper** Manager of the General Partner's general partner. i Filing they signed

We also hold **41** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$1.9B** gross assets of its funds Oct 2026

**Exempt** reporting adviser venture or small private funds

- **Legal name:** Third ROCK Ventures, LLC
- **SEC number:** CRD 161185

## What they claim to have backed

From their own portfolio page (on their website)

**0** of 1 we have independently watched raise

Syremis

Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.

## Exits from the portfolio

Companies it backed that were later bought or listed **5 in all**

**[Foundation Medicine](https://millionrounds.com/company/foundation-medicine)** Bought by Roche **Undisclosed** Jan 2015

**[Foundation Medicine](https://millionrounds.com/company/foundation-medicine)** Listed **$108M** Jul 2013

**[bluebird bio](https://millionrounds.com/company/bluebird-bio)** Listed **$101M** Jun 2013

**[Agios Pharmaceuticals](https://millionrounds.com/company/agios-pharmaceuticals)** Listed **$86M** Jun 2013

**[Alnara Pharmaceuticals](https://millionrounds.com/company/alnara-pharmaceuticals)** Bought by [Eli Lilly](https://millionrounds.com/fund/eli-lilly) **Undisclosed** Jul 2010

An exit counts when it came after the firm's first round in the company. From historical deal records.

New fund on file

**$1.1B**

raised in Jun 2026

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Pre-seed

Median round joined **$56M** the round, not its cheque Alone, median **$47M**

Led 1 of 84 rounds **1%**

- **Said size:** $5.0M – $100M
- **Sole investor:** 15 rounds
- **Last cheque:** Jul 2019
- **Exits:** 5 from the portfolio

Rounds by stage said on their site

- Series A *39*
- Series B *24*
- Series C *8*
- Growth *4*
- Series D *3*
- Pre-seed said *-*

Cheques by year Led Joined

2008 2019

Often in the room with

- [The Column Group](https://millionrounds.com/fund/the-column-group) 11
- [Casdin Capital](https://millionrounds.com/fund/casdin-capital) 8
- [Polaris Partners](https://millionrounds.com/fund/polaris-partners) 8
- [Flagship Pioneering, LLC](https://millionrounds.com/fund/flagship-pioneering-llc) 7
- [OrbiMed](https://millionrounds.com/fund/orbimed) 7
- [ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) 6

**Pitching Third Rock Ventures?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as Third Rock Ventures. A count of rooms they were both in, not a relationship either has claimed.

[**The Column Group** VC firm **11** rounds together](https://millionrounds.com/fund/the-column-group)[**Casdin Capital** VC firm **8** rounds together](https://millionrounds.com/fund/casdin-capital)[**Polaris Partners** VC firm **8** rounds together](https://millionrounds.com/fund/polaris-partners)[**Flagship Pioneering, LLC** VC firm **7** rounds together](https://millionrounds.com/fund/flagship-pioneering-llc)[**OrbiMed** Private equity **7** rounds together](https://millionrounds.com/fund/orbimed)[**ARCH Venture Partners** VC firm **6** rounds together](https://millionrounds.com/fund/arch-venture-partners)[**Deerfield** VC firm **6** rounds together](https://millionrounds.com/fund/deerfield)[**Bessemer Venture Partners** VC firm **5** rounds together](https://millionrounds.com/fund/bessemer-venture-partners)[**Frazier Healthcare Partners** Private equity **5** rounds together](https://millionrounds.com/fund/frazier-healthcare-partners)[**Pfizer** Corporate VC **5** rounds together](https://millionrounds.com/fund/pfizer)[**SR One** Corporate VC **5** rounds together](https://millionrounds.com/fund/sr-one)[**Venrock** VC firm **5** rounds together](https://millionrounds.com/fund/venrock)

## Recently backed

The latest companies Third Rock Ventures put money into.

[**Revolution Medicines** $100M · Jul 2019](https://millionrounds.com/company/revolution-medicines)[**Decibel Therapeutics** $55M · Jun 2018](https://millionrounds.com/company/decibel-therapeutics)[**Cedilla Therapeutics** $56M · Apr 2018](https://millionrounds.com/company/cedilla-therapeutics)[**Constellation** $100M · Apr 2018](https://millionrounds.com/company/constellation)[**Relay** $63M · Dec 2017](https://millionrounds.com/company/relay)[**Tango Therapeutics** $55M · Mar 2017](https://millionrounds.com/company/tango-therapeutics)

## Quick answers about Third Rock Ventures

### What does Third Rock Ventures invest in?

Third Rock Ventures invests most often at Series A and Series B (81% of the rounds on record), in sectors such as Biotech, Pharmaceuticals and Bio.

### How active is Third Rock Ventures?

84 investments on record, 0 of them in the last 12 months, and it led 1. The most recent was in Jul 2019.

### What has Third Rock Ventures invested in recently?

Its most recent investments on record: Revolution Medicines (Series C, Jul 2019), Thrive (Series A, May 2019) and Public food doctor (Undisclosed round, Apr 2019).

### How big are Third Rock Ventures's cheques?

The median round it joins is $56M. It says it writes cheques of $5.0M to $100M.

### Does Third Rock Ventures lead rounds?

Sometimes: it led 1 of its 84 investments on record (1%).

### Where does Third Rock Ventures invest?

Most of the companies it backs are in the United States (95%).

### Is Third Rock Ventures investing now?

No investments in the last 12 months; the latest was in Jul 2019.

### Who does Third Rock Ventures invest alongside?

Most often The Column Group (11 rounds together), Casdin Capital (8 rounds together) and Polaris Partners (8 rounds together).

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