# TCG Crossover: portfolio, investments and team

> TCG Crossover is a vc firm based in United States. 60 investments on record, 30 in the last 12 months, latest Oct 2026.

Source: https://millionrounds.com/fund/tcg-crossover (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# TCG Crossover

Last cheque observed Oct 2026; 60 cheques on record.

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Deploying now New fund $800M, Jun 2025 VC firm

Seed Series A Series B Well-being Therapeutics Drugs

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Deploying now

**91%** of best year **30** **cheques in 12 months**, 60 on record

Since the last cheque **8** days **00** hrs **00** min **00** sec

Median round **$150M** Rounds led **4 of 60** Mostly in **United States, 77%**

Pitch TCG Crossover

## TCG Crossover highlights

- 01 30 cheques in the last 12 months
- 02 Mostly Series B and Series C: 64% of its rounds
- 03 Led 4 rounds

## What they do

> TCG Crossover (“TCGX”) is a science-driven investment firm dedicated to advancing disruptive medicines From their own website

- **Type:** VC firm
- **Cheque size:** Not stated
- **Stages:** Seed Series A Series B Growth Pre-IPO
- **Sectors:** Well-being Therapeutics Drugs
- **Based in:** Palo Alto, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **60 appearances**

- **2026** 25 rounds
- **Oct** **[Zai Lab](https://millionrounds.com/company/zai-lab)** CN · Pulse 2.0 **$250M** *Led*
- **Oct** **[ADC Therapeutics](https://millionrounds.com/company/adc-therapeutics)** CH · Pulse 2.0 **$87M** With 3 others
- **Oct** **[TriGemX Bio](https://millionrounds.com/company/trigemx-bio)** US · AlleyWatch **$94M** *Led*
- **Sept** **[Tyra Biosciences](https://millionrounds.com/company/tyra-biosciences)** US **$400M** With 5 others
- **Sept** **[AN2 Therapeutics](https://millionrounds.com/company/an2-therapeutics)** Grant · US **$40M** With 4 others
- **Aug** **[Vaderis Therapeutics](https://millionrounds.com/company/vaderis-therapeutics)** Series B · CH · Firms' own news pages **$152M** *Led*
- **Jul** **[LB Pharmaceuticals](https://millionrounds.com/company/lb-pharmaceuticals)** US **$150M** With 2 others
- **Jun** **[Ollin Biosciences](https://millionrounds.com/company/ollin-biosciences)** Series B · US **$330M** With 4 others
- **Jun** **[Mineralys Therapeutics](https://millionrounds.com/company/mineralys-therapeutics)** Debt · US **$500M** With 5 others
- **May** **[Accro Bioscience](https://millionrounds.com/company/accro-bioscience)** Series C · CN · Ventureburn **$50M** With 5 others
- **May** **[Mirum Pharmaceuticals](https://millionrounds.com/company/mirum-pharmaceuticals)** Debt · US **$600M** With 3 others
- **May** **[Avalo Therapeutics](https://millionrounds.com/company/avalo-therapeutics)** US **$431M** With 3 others
- **May** **[Abivax](https://millionrounds.com/company/abivax)** FR **$45M** With 4 others
- **Apr** **[Adcendo](https://millionrounds.com/company/adcendo)** Series C · DK · Ventureburn **$75M** With 9 others
- **Apr** **[Maze Therapeutics](https://millionrounds.com/company/maze-therapeutics)** US **$150M** With 5 others
- **Apr** **[Valneva](https://millionrounds.com/company/valneva)** FR **$43M** With 4 others
- **Mar** **[Inhibrx](https://millionrounds.com/company/inhibrx)** Debt · US **$75M** With 4 others
- **Mar** **[Vor Biopharma](https://millionrounds.com/company/vor-biopharma)** US **$75M** With 2 others
- **Feb** **[Perspective Therapeutics](https://millionrounds.com/company/perspective-therapeutics)** US **$175M** With 2 others
- **Feb** **[Immunic Therapeutics](https://millionrounds.com/company/immunic-therapeutics)** US **$400M** With 5 others
- **Feb** **[LB Pharmaceuticals](https://millionrounds.com/company/lb-pharmaceuticals)** US **$100M** With 1 other
- **Jan** **[CORXEL Pharmaceuticals](https://millionrounds.com/company/corxel-pharmaceuticals)** Series D **$287M** With 5 others
- **Jan** **[Mirador Therapeutics](https://millionrounds.com/company/mirador-therapeutics)** Series B · US **$250M** With 6 others
- **Jan** **[Beacon Therapeutics](https://millionrounds.com/company/beacon-therapeutics)** Series C · US **$75M** With 4 others
- **Jan** **[Century Therapeutics](https://millionrounds.com/company/century-therapeutics)** US **$135M** With 7 others
- **2025** 19 rounds
- **Dec** **[Immunovant](https://millionrounds.com/company/immunovant)** US **$550M** With 1 other
- **Dec** **[Mirum Pharmaceuticals](https://millionrounds.com/company/mirum-pharmaceuticals)** US **$69M** With 3 others
- **Dec** **[Structure Therapeutics](https://millionrounds.com/company/structure-therapeutics)** US **$748M** With 6 others
- **Dec** **[Athira Pharma](https://millionrounds.com/company/athira-pharma)** US **$90M** With 4 others
- **Nov** **[Cogent Biosciences](https://millionrounds.com/company/cogent-biosciences)** Debt · US **$200M** With 6 others
- **Oct** **[Affinia Therapeutics](https://millionrounds.com/company/affinia-therapeutics)** Series C · US **$40M** With 5 others
- **Oct** **[Disc Medicine](https://millionrounds.com/company/disc-medicine)** US **$225M** With 5 others
- **Oct** **[Cidara Therapeutics](https://millionrounds.com/company/cidara-therapeutics)** Grant · US **$339M** With 5 others
- **Oct** **[ADC Therapeutics](https://millionrounds.com/company/adc-therapeutics)** CH **$60M** With 3 others
- **Oct** **[Rapt Therapeutics](https://millionrounds.com/company/rapt-therapeutics)** US **$250M** With 6 others
- **Sept** **[Maze Therapeutics](https://millionrounds.com/company/maze-therapeutics)** US **$150M** With 4 others
- **Sept** **[Korsana Biosciences](https://millionrounds.com/company/korsana-biosciences)** Series A · US **$150M** With 5 others
- **Sept** **[Mineralys Therapeutics](https://millionrounds.com/company/mineralys-therapeutics)** US **$288M** With 5 others
- **Aug** **[Plexium](https://millionrounds.com/company/plexium)** Series C · US **$60M** With 7 others
- **Jul** **[Abivax](https://millionrounds.com/company/abivax)** FR **$748M** With 3 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **2 named**

CM **Chen Ming Yu** Managing Member of the General Partner i Filing they signed

CD **Craig David Skaling** Chief Operating Officer and Chief Compliance Officer i Form ADV

We also hold **12** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$5.1B** assets it manages Oct 2026

**Registered** investment adviser full reporting to the SEC

- **Legal name:** TCG Crossover Management, LLC
- **SEC number:** CRD 311718

Funds on its Form ADV

**2** private funds, **$2.2B** in gross assets · filed Mar 2024

- TCG Crossover Fund I, L.P. *Hybrid fund* 80 investors $1.3B
- TCG Crossover Fund II, L.P. *Hybrid fund* 98 investors $892M

## What they claim to have backed

From their own portfolio page (on their website)

**13** of 17 we have independently watched raise

[Adcendo](https://millionrounds.com/company/adcendo)[Aktisoncology](https://millionrounds.com/company/aktis-oncology)[Arbor](https://millionrounds.com/company/arbor)[Artiospharma](https://millionrounds.com/company/artios-pharma)[Carmot](https://millionrounds.com/company/carmot)[Cgoncology](https://millionrounds.com/company/cg-oncology)[Plexium](https://millionrounds.com/company/plexium)[Rayzebio](https://millionrounds.com/company/rayzebio)[Synthekine](https://millionrounds.com/company/synthekine)[Tourmalinebio](https://millionrounds.com/company/tourmaline-bio)[Upstreambio](https://millionrounds.com/company/upstream-bio)[Versanisbio](https://millionrounds.com/company/versanis-bio)[Vicebio](https://millionrounds.com/company/vicebio) Alkeuspharma Korsana Ollin Shoutipharma

Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.

New fund on file

**$800M**

raised in Jun 2025

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Seed Series A Series B

Median round joined **$150M** the round, not its cheque

Led 4 of 60 rounds **7%**

- **Sole investor:** Never alone
- **Last cheque:** Oct 2026

Rounds by stage said on their site

- Series B said *8*
- Series C *8*
- Debt *5*
- Series A said *2*
- Grant *2*
- Seed said *-*
- Growth said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [TCG](https://millionrounds.com/fund/tcg) 56
- [RA Capital Management](https://millionrounds.com/fund/ra-capital-management) 21
- [Janus Henderson Investors](https://millionrounds.com/fund/janus-henderson-investors) 14
- [OrbiMed](https://millionrounds.com/fund/orbimed) 13
- [Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) 9
- [Vivo Capital](https://millionrounds.com/fund/vivo-capital) 9

**Pitching TCG Crossover?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as TCG Crossover. A count of rooms they were both in, not a relationship either has claimed.

[**TCG** Private equity **56** rounds together](https://millionrounds.com/fund/tcg)[**RA Capital Management** Private equity **21** rounds together](https://millionrounds.com/fund/ra-capital-management)[**Janus Henderson Investors** Private equity **14** rounds together](https://millionrounds.com/fund/janus-henderson-investors)[**OrbiMed** Private equity **13** rounds together](https://millionrounds.com/fund/orbimed)[**Perceptive Advisors** Asset manager **9** rounds together](https://millionrounds.com/fund/perceptive-advisors)[**Vivo Capital** Private equity **9** rounds together](https://millionrounds.com/fund/vivo-capital)[**RTW Investments LLC** Growth equity **8** rounds together](https://millionrounds.com/fund/rtw-investments-lp)[**Wellington Management** VC firm **8** rounds together](https://millionrounds.com/fund/wellington-management)[**Samsara BioCapital** VC firm **7** rounds together](https://millionrounds.com/fund/samsara-biocapital)[**Adage Capital Management** Asset manager **6** rounds together](https://millionrounds.com/fund/adage-capital-management)[**Cormorant Asset Management** Private equity **6** rounds together](https://millionrounds.com/fund/cormorant-asset-management)[**Novo Holdings** VC firm **6** rounds together](https://millionrounds.com/fund/novo-ventures)

## Recently backed

The latest companies TCG Crossover put money into.

[**ADC Therapeutics** $87M · Oct 2026](https://millionrounds.com/company/adc-therapeutics)[**Tyra Biosciences** $400M · Sept 2026](https://millionrounds.com/company/tyra-biosciences)[**AN2 Therapeutics** $40M · Sept 2026](https://millionrounds.com/company/an2-therapeutics)[**LB Pharmaceuticals** $150M · Jul 2026](https://millionrounds.com/company/lb-pharmaceuticals)[**Ollin Biosciences** $330M · Jun 2026](https://millionrounds.com/company/ollin-biosciences)[**Mineralys Therapeutics** $500M · Jun 2026](https://millionrounds.com/company/mineralys-therapeutics)

## Quick answers about TCG Crossover

### What does TCG Crossover invest in?

TCG Crossover invests most often at Series B and Series C (64% of the rounds on record), in sectors such as Well-being, Therapeutics and Drugs.

### How active is TCG Crossover?

60 investments on record, 30 of them in the last 12 months, and it led 4. The most recent was in Oct 2026.

### What has TCG Crossover invested in recently?

Its most recent investments on record: Zai Lab (Undisclosed round, Oct 2026), ADC Therapeutics (Undisclosed round, Oct 2026) and TriGemX Bio (Undisclosed round, Oct 2026).

### How big are TCG Crossover's cheques?

The median round it joins is $150M.

### Does TCG Crossover lead rounds?

Sometimes: it led 4 of its 60 investments on record (7%).

### Where does TCG Crossover invest?

Most of the companies it backs are in the United States (77%), Switzerland (8%) and France (8%).

### Is TCG Crossover investing now?

Yes: it is actively investing, with 30 investments in the last 12 months.

### Who does TCG Crossover invest alongside?

Most often TCG (56 rounds together), RA Capital Management (21 rounds together) and Janus Henderson Investors (14 rounds together).

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