# Safeguard Scientifics: portfolio, investments and team

> Safeguard Scientifics is a private equity based in United States. 85 investments on record, latest May 2023. Portfolio, stages, co-investors and team.

Source: https://millionrounds.com/fund/safeguard-scientifics (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Safeguard Scientifics

Last cheque observed May 2023. Silence since then is not evidence of inactivity: our sources miss unannounced rounds.

Quiet Private equity Website unconfirmed

Seed Series A Series B Telehealth Health-tech Wellness

Cheques on record

**0%** of best year **0** **cheques in 12 months**, 85 on record

Since the last cheque **1264** days **00** hrs **00** min **00** sec

Median round **$11M** Cheque size, as they say **$2.0M – $15M** Rounds led **2 of 85** Sole investor **21 rounds** Exits **17 from the portfolio** Mostly in **United States, 100%**

Pitch Safeguard Scientifics

## Safeguard Scientifics highlights

- 01 85 rounds on record
- 02 Mostly Series B and Series A: 66% of its rounds
- 03 Sole investor in 21 rounds, median $6.0M
- 04 17 exits from the portfolio

## What they do

- **Type:** Private equity (from a list, unverified)
- **Cheque size:** $2.0M – $15M as they say
- **Stages:** Seed Series A Series B Growth Pre-IPO
- **Sectors:** Telehealth Health-tech Wellness
- **Based in:** Radnor, United States
- **Cold pitches:** Not stated

A website was listed for this organisation, but we could not confirm it belongs to the firm that wrote these cheques. Either the site never mentions them, or it turned out to be a different company sharing the name. We show neither it nor anything read from it. [Tell us the right one](https://millionrounds.com/corrections?slug=safeguard-scientifics).

## The record

Every round we can evidence, newest first **85 appearances**

- **2023** 1 round
- **May** **[Prognos Health](https://millionrounds.com/company/prognos-health)** Growth · US · Cigna Ventures **$23M** *Led*
- **2017** 4 rounds
- **Nov** **[Syapse](https://millionrounds.com/company/syapse)** Series D · US · FinSMEs **$30M** With 8 others
- **Jun** **[Trice Medical](https://millionrounds.com/company/trice-medical)** Series C · US · FinSMEs **$19M** With 3 others
- **May** **[T-Rex Group](https://millionrounds.com/company/t-rex-group)** Series B · US · FinSMEs **$10M** With 3 others
- **Mar** **[Velano Vascular](https://millionrounds.com/company/velano-vascular)** US · FinSMEs **$17M** With 5 others
- **2016** 6 rounds
- **Nov** **[T-REX](https://millionrounds.com/company/t-rex)** Series B · US · FinSMEs **$10M** Sole investor
- **Nov** **[Spongecell](https://millionrounds.com/company/spongecell)** Debt · US · FinSMEs **$11M** With 1 other
- **Oct** **[Brickwork](https://millionrounds.com/company/brickwork)** Series A · US · FinSMEs **$5.0M** Sole investor
- **Oct** **[Moxe Health](https://millionrounds.com/company/moxe-health)** Series A · US · FinSMEs **$5.5M** Sole investor
- **Jul** **[InfoBionic](https://millionrounds.com/company/infobionic)** Series B · US · Massdevice **$8.2M** Sole investor
- **Jun** **[Aktana](https://millionrounds.com/company/aktana)** US · Prnewswire **$18M** *Led*
- **2015** 11 rounds
- **Nov** **[Cask](https://millionrounds.com/company/cask)** Series B · US **$20M** With 2 others
- **Aug** **[InfoBionic](https://millionrounds.com/company/infobionic)** Series B · US **$8.0M** With 2 others
- **Aug** **[Sonobi](https://millionrounds.com/company/sonobi)** Series A · US **$10M** Sole investor
- **Jul** **[Apprenda](https://millionrounds.com/company/apprenda)** Series D · US **$24M** With 2 others
- **Jul** **[Pneuron](https://millionrounds.com/company/pneuron)** Series B · US **$5.0M** With 1 other
- **May** **[Clutch](https://millionrounds.com/company/clutch)** Series B · US **$5.0M** Sole investor
- **Apr** **[Full Measure Education](https://millionrounds.com/company/full-measure-education)** Series B · US **$5.5M** With 1 other
- **Apr** **[meQuilibrium](https://millionrounds.com/company/mequilibrium)** Series B · US **$9.0M** With 1 other
- **Mar** **[CloudMine](https://millionrounds.com/company/cloudmine)** Series A · US **$7.2M** With 6 others
- **Feb** **[Aventura](https://millionrounds.com/company/aventura)** Series C · US **$14M** With 4 others
- **Feb** **[Velano Vascular](https://millionrounds.com/company/velano-vascular)** Series A · US **$5.0M** With 3 others
- **2014** 9 rounds
- **Sept** **[Propeller Health](https://millionrounds.com/company/propeller-health)** Series B · US **$15M** With 2 others
- **Aug** **[Transactis](https://millionrounds.com/company/transactis)** Series D · US **$11M** With 1 other
- **Aug** **[WebLinc](https://millionrounds.com/company/weblinc)** Series A · US **$6.0M** Sole investor
- **Jul** **[Trice Medical](https://millionrounds.com/company/trice-medical)** Series B · US **$12M** With 2 others
- **Jul** **[Syapse](https://millionrounds.com/company/syapse)** Series B · US **$10M** With 2 others
- **Jun** **[Lumesis, Inc.](https://millionrounds.com/company/lumesis-inc)** Series B · US **$2.0M** Sole investor
- **May** **[MediaMath](https://millionrounds.com/company/mediamath)** Series C · US **$74M** With 3 others
- **Apr** **[InfoBionic](https://millionrounds.com/company/infobionic)** Series B · US **$17M** With 9 others
- **Feb** **[Hoopla](https://millionrounds.com/company/hoopla)** Series B · US **$8.0M** With 2 others
- **2013** 8 rounds
- **Nov** **[Apprenda](https://millionrounds.com/company/apprenda)** Series C · US · finsmes.com **$16M** With 2 others
- **Nov** **[Dabo Health](https://millionrounds.com/company/dabo-health)** Series A · US · sec.gov **$2.0M** Sole investor
- **Aug** **[Clutch](https://millionrounds.com/company/clutch)** Series B · US · sec.gov **$10M** With 1 other
- **Aug** **[Quantia](https://millionrounds.com/company/quantia)** Series B · US · bostonglobe.com **$10M** With 1 other
- **Jun** **[Medivo](https://millionrounds.com/company/medivo)** Series B · US · finsmes.com **$15M** With 2 others
- **Mar** **[Pneuron](https://millionrounds.com/company/pneuron)** Series B · US · finsmes.com **$6.0M** With 1 other
- **Feb** **[Sotera Wireless](https://millionrounds.com/company/sotera-wireless)** Series D · US · pevc.dowjones.com **$15M** With 6 others
- **Jan** **[Crescendo Bioscience](https://millionrounds.com/company/crescendo-bioscience)** Series D · US · pevc.dowjones.com **$28M** With 4 others
- **2012** 5 rounds
- **Dec** **[AppFirst](https://millionrounds.com/company/appfirst)** Series B · US **$8.7M** With 2 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

We hold **15** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## Exits from the portfolio

Companies it backed that were later bought or listed **17 in all**

**[Cask](https://millionrounds.com/company/cask)** Bought by [Google](https://millionrounds.com/fund/google-assistant-investments) **Undisclosed** May 2018

**[DriveFactor](https://millionrounds.com/company/drivefactor)** Bought by CCC Information Services **$22M** May 2015

**[Crescendo Bioscience](https://millionrounds.com/company/crescendo-bioscience)** Bought by [Myriad Genetics](https://millionrounds.com/fund/myriad-genetics) **$270M** Feb 2014

**[Alverix](https://millionrounds.com/company/alverix)** Bought by Becton Dickinson **$40M** Jan 2014

**[ThingWorx](https://millionrounds.com/company/thingworx)** Bought by [Parametric Technology (PTC)](https://millionrounds.com/fund/parametric-technology-ptc) **$112M** Dec 2013

**[NuPathe](https://millionrounds.com/company/nupathe)** Bought by Endo Health Solutions **$105M** Dec 2013

**[Swaptree Inc.](https://millionrounds.com/company/swaptree-inc)** Bought by NetCycler **Undisclosed** Sept 2012

**[Portico Systems](https://millionrounds.com/company/portico-systems)** Bought by [McKesson](https://millionrounds.com/fund/mckesson) **Undisclosed** Jun 2011

**[Advanced BioHealing](https://millionrounds.com/company/advanced-biohealing)** Bought by [Shire](https://millionrounds.com/fund/shire) **$750M** May 2011

**[Avid Radiopharmaceuticals](https://millionrounds.com/company/avid-radiopharmaceuticals)** Bought by [Eli Lilly](https://millionrounds.com/fund/eli-lilly) **$800M** Nov 2010

**[NuPathe](https://millionrounds.com/company/nupathe)** Listed **Undisclosed** Aug 2010

**[Authentium](https://millionrounds.com/company/authentium)** Bought by CYREN **$8.0M** Jul 2010

**[Tengion](https://millionrounds.com/company/tengion)** Listed **Undisclosed** Apr 2010

**[Acsis](https://millionrounds.com/company/acsis)** Bought by [Saints Capital](https://millionrounds.com/fund/saints-capital) **Undisclosed** May 2008

**[NextPoint Networks](https://millionrounds.com/company/nextpoint-networks)** Bought by [Saints Capital](https://millionrounds.com/fund/saints-capital) **Undisclosed** May 2008

**[Mantas](https://millionrounds.com/company/mantas)** Bought by i-flex Solutions **Undisclosed** Oct 2006

**[RedSiren](https://millionrounds.com/company/redsiren)** Bought by Getronics **Undisclosed** Mar 2005

An exit counts when it came after the firm's first round in the company. From historical deal records.

## Companies it bought

Acquisitions by the firm itself

**[Acsis](https://millionrounds.com/company/acsis)** **$26M** Dec 2005

## The cheque

Seed Series A Series B

Median round joined **$11M** the round, not its cheque Alone, median **$6.0M**

Led 2 of 85 rounds **2%**

- **Said size:** $2.0M – $15M
- **Sole investor:** 21 rounds
- **Last cheque:** May 2023
- **Exits:** 17 from the portfolio

Rounds by stage said on their site

- Series B said *31*
- Series A said *22*
- Series D *11*
- Series C *11*
- Venture *5*
- Seed said *-*
- Growth said *-*

Cheques by year Led Joined

2001 2023

Often in the room with

- [Constellation Ventures](https://millionrounds.com/fund/constellation-ventures) 4
- [Merck Global Health Innovation Fund](https://millionrounds.com/fund/merck-global-health-innovation-fund) 4
- [BioAdvance](https://millionrounds.com/fund/bioadvance-capital) 3
- [Ignition Partners](https://millionrounds.com/fund/ignition-partners) 3
- [MentorTech Ventures](https://millionrounds.com/fund/mentortech-ventures) 3
- [QED Investors](https://millionrounds.com/fund/qed-investors) 3

**Pitching Safeguard Scientifics?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as Safeguard Scientifics. A count of rooms they were both in, not a relationship either has claimed.

[**Constellation Ventures** VC firm **4** rounds together](https://millionrounds.com/fund/constellation-ventures)[**Merck Global Health Innovation Fund** Corporate VC **4** rounds together](https://millionrounds.com/fund/merck-global-health-innovation-fund)[**BioAdvance** VC firm **3** rounds together](https://millionrounds.com/fund/bioadvance-capital)[**Ignition Partners** VC firm **3** rounds together](https://millionrounds.com/fund/ignition-partners)[**MentorTech Ventures** VC firm **3** rounds together](https://millionrounds.com/fund/mentortech-ventures)[**QED Investors** VC firm **3** rounds together](https://millionrounds.com/fund/qed-investors)[**Quaker Partners** VC firm **3** rounds together](https://millionrounds.com/fund/quaker-partners)[**Social Capital** VC firm **3** rounds together](https://millionrounds.com/fund/social-capital)[**AllianceBernstein** VC firm **2** rounds together](https://millionrounds.com/fund/alliancebernstein)[**Bahrain Middle East Bank** VC firm **2** rounds together](https://millionrounds.com/fund/bahrain-middle-east-bank)[**Battelle Ventures** VC firm **2** rounds together](https://millionrounds.com/fund/battelle-ventures)[**Delphi Ventures** VC firm **2** rounds together](https://millionrounds.com/fund/delphi-ventures)

## Recently backed

The latest companies Safeguard Scientifics put money into.

[**Syapse** $30M · Nov 2017](https://millionrounds.com/company/syapse)[**Trice Medical** $19M · Jun 2017](https://millionrounds.com/company/trice-medical)[**T-REX** $10M · Nov 2016](https://millionrounds.com/company/t-rex)[**Spongecell** $11M · Nov 2016](https://millionrounds.com/company/spongecell)[**Brickwork** $5.0M · Oct 2016](https://millionrounds.com/company/brickwork)[**Moxe Health** $5.5M · Oct 2016](https://millionrounds.com/company/moxe-health)

## Quick answers about Safeguard Scientifics

### What does Safeguard Scientifics invest in?

Safeguard Scientifics invests most often at Series B and Series A (66% of the rounds on record), in sectors such as Telehealth, Health-tech and Wellness.

### How active is Safeguard Scientifics?

85 investments on record, 0 of them in the last 12 months, and it led 2. The most recent was in May 2023.

### What has Safeguard Scientifics invested in recently?

Its most recent investments on record: Prognos Health (Growth, May 2023), Syapse (Series D, Nov 2017) and Trice Medical (Series C, Jun 2017).

### How big are Safeguard Scientifics's cheques?

The median round it joins is $11M. It says it writes cheques of $2.0M to $15M.

### Does Safeguard Scientifics lead rounds?

Sometimes: it led 2 of its 85 investments on record (2%).

### Where does Safeguard Scientifics invest?

Most of the companies it backs are in the United States (100%).

### Is Safeguard Scientifics investing now?

No investments in the last 12 months; the latest was in May 2023.

### Who does Safeguard Scientifics invest alongside?

Most often Constellation Ventures (4 rounds together), Merck Global Health Innovation Fund (4 rounds together) and BioAdvance (3 rounds together).

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