# RTW Investments LLC: portfolio, investments and team

> RTW Investments LLC is a growth equity based in United States. 87 investments on record, 33 in the last 12 months, latest Oct 2026.

Source: https://millionrounds.com/fund/rtw-investments-lp (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# RTW Investments LLC

Last cheque observed Oct 2026; 87 cheques on record.

Deploying now Growth equity

Series B Venture Series A Internet Ride Sharing Business Development

Deploying now

**85%** of best year **33** **cheques in 12 months**, 87 on record

Since the last cheque **3** days **00** hrs **00** min **00** sec

Median round **$125M** Rounds led **2 of 87** Sole investor **5 rounds** Mostly in **United States, 84%**

Pitch RTW Investments LLC

## RTW Investments LLC highlights

- 01 33 cheques in the last 12 months
- 02 Mostly Series B and Venture: 54% of its rounds
- 03 Sole investor in 5 rounds, median $108M

## What they do

- **Type:** Growth equity (from a list, unverified)
- **Cheque size:** Not stated
- **Sectors:** Internet Ride Sharing Business Development
- **Based in:** New York, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **87 appearances**

- **2026** 22 rounds
- **Oct** **[Zai Lab](https://millionrounds.com/company/zai-lab)** CN · Pulse 2.0 **$250M** With 10 others
- **Sept** **[Pyxis Oncology](https://millionrounds.com/company/pyxis-oncology)** US **$110M** With 4 others
- **Jun** **[MoonLake Immunotherapeutics](https://millionrounds.com/company/moonlake-immunotherapeutics)** CH **$200M** With 2 others
- **May** **[Orchestra BioMed](https://millionrounds.com/company/orchestra-biomed)** Debt · US **$35M** With 1 other
- **May** **[Ocugen](https://millionrounds.com/company/ocugen)** Debt · US **$115M** With 1 other
- **May** **[Whitehawk Therapeutics](https://millionrounds.com/company/whitehawk-therapeutics)** US **$88M** With 2 others
- **Apr** **[Spyre Therapeutics](https://millionrounds.com/company/spyre-therapeutics)** US **$403M** With 3 others
- **Apr** **[ImageneBio](https://millionrounds.com/company/imagenebio)** US **$30M** With 4 others
- **Apr** **[Oruka Therapeutics](https://millionrounds.com/company/oruka-therapeutics)** US **$700M** With 3 others
- **Apr** **[GH Research](https://millionrounds.com/company/gh-research)** IE **$118M** With 4 others
- **Mar** **[Dianthus Therapeutics](https://millionrounds.com/company/dianthus-therapeutics)** US **$719M** With 3 others
- **Mar** **[SAB Biotherapeutics](https://millionrounds.com/company/sab-biotherapeutics)** US **$85M** With 3 others
- **Mar** **[Amani Therapeutics](https://millionrounds.com/company/amani-therapeutics)** Series A · US **$25M** Sole investor
- **Mar** **[Prolium](https://millionrounds.com/company/prolium)** Series A · US **$50M** Sole investor
- **Feb** **[Evommune](https://millionrounds.com/company/evommune)** US **$125M** With 5 others
- **Feb** **[Immunic Therapeutics](https://millionrounds.com/company/immunic-therapeutics)** US **$400M** With 5 others
- **Jan** **[Oricell Therapeutics](https://millionrounds.com/company/oricell-therapeutics)** Series C **$70M** With 1 other
- **Jan** **[Ocugen](https://millionrounds.com/company/ocugen)** US **$23M** With 1 other
- **Jan** **[CORXEL Pharmaceuticals](https://millionrounds.com/company/corxel-pharmaceuticals)** Series D **$287M** With 5 others
- **Jan** **[Monte Rosa Therapeutics](https://millionrounds.com/company/monte-rosa-therapeutics)** CH **$300M** With 5 others
- **Jan** **[Mirador Therapeutics](https://millionrounds.com/company/mirador-therapeutics)** Series B · US **$250M** With 6 others
- **Jan** **[Century Therapeutics](https://millionrounds.com/company/century-therapeutics)** US **$135M** With 7 others
- **2025** 28 rounds
- **Dec** **[Kalaris Therapeutics](https://millionrounds.com/company/kalaris-therapeutics)** US **$50M** With 3 others
- **Dec** **[Kyverna Therapeutics](https://millionrounds.com/company/kyverna-therapeutics)** US **$100M** With 2 others
- **Dec** **[Jade Biosciences](https://millionrounds.com/company/jade-biosciences)** US **$45M** With 4 others
- **Dec** **[Tenaya Therapeutics](https://millionrounds.com/company/tenaya-therapeutics)** US **$60M** With 3 others
- **Dec** **[Crescent Biopharma](https://millionrounds.com/company/crescent-biopharma)** US **$185M** With 4 others
- **Dec** **[Belite Bio](https://millionrounds.com/company/belite-bio)** US **$350M** With 1 other
- **Dec** **[Yarrow](https://millionrounds.com/company/yarrow)** Venture · US **$200M** With 3 others
- **Nov** **[Cogent Biosciences](https://millionrounds.com/company/cogent-biosciences)** Debt · US **$200M** With 6 others
- **Nov** **[Verastem Oncology](https://millionrounds.com/company/verastem-oncology)** US **$90M** With 4 others
- **Nov** **[MoonLake Immunotherapeutics](https://millionrounds.com/company/moonlake-immunotherapeutics)** CH **$75M** With 2 others
- **Nov** **[Artios Pharma](https://millionrounds.com/company/artios-pharma)** Series D · GB **$115M** With 5 others
- **Oct** **[Kailera Therapeutics](https://millionrounds.com/company/kailera-therapeutics)** Series B · US · Crunchbase News **$600M** With 9 others
- **Oct** **[Rapt Therapeutics](https://millionrounds.com/company/rapt-therapeutics)** US **$250M** With 6 others
- **Oct** **[Biomea Fusion](https://millionrounds.com/company/biomea-fusion)** US **$25M** With 2 others
- **Oct** **[Spyre Therapeutics](https://millionrounds.com/company/spyre-therapeutics)** US **$275M** With 3 others
- **Sept** **[Mineralys Therapeutics](https://millionrounds.com/company/mineralys-therapeutics)** US **$288M** With 5 others
- **Sept** **[Ensoma](https://millionrounds.com/company/ensoma)** Venture · US **$53M** With 2 others
- **Sept** **[Oruka Therapeutics](https://millionrounds.com/company/oruka-therapeutics)** US **$180M** With 3 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **9 named**

CJ **Christopher John Seiter** Chief Corporate Finance Officer i Form ADV

DV **Darshan Vishnu Patel** Chief Compliance Officer i Form ADV

GM **Gotam Makker** Partner, Head of Strategic Investments i Form ADV

NY **Naveen Yalamanchi** Partner, Portfolio Manager i Form ADV

PM **Peter M Fong** Partner, President i Form ADV

RJ **Robert John Aurigema** Partner, Chief Operating Officer and Chief Financial Officer i Form ADV

RT **Roderick Tze Ian Wong** Managing Partner, Chief Investment Officer i Form ADV

SR **Sabera Reza Loughran** Partner Emeritus i Form ADV

SA **Stephanie Anne Sirota** Partner, Chief Business Officer i Form ADV

We also hold **18** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$14B** assets it manages Oct 2026

**Registered** investment adviser full reporting to the SEC

- **Legal name:** RTW Investments LP
- **SEC number:** CRD 153232

Funds on its Form ADV

**3** private funds, **$8.4B** in gross assets · filed Mar 2024

Hedge **2** Private equity **1**

- RTW Master Fund, LTD. *Hedge* 1,418 investors $5.1B
- RTW Innovation Master Fund, LTD. *Hedge* 349 investors $3.3B
- 4010 Royalty Investments ICAV *Private equity* 35 investors $81M

## The cheque

Series B Venture Series A

Median round joined **$125M** the round, not its cheque Alone, median **$108M**

Led 2 of 87 rounds **2%**

- **Sole investor:** 5 rounds
- **Last cheque:** Oct 2026

Rounds by stage said on their site

- Series B *11*
- Venture *8*
- Series A *6*
- Series C *5*
- Series D *5*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [RA Capital Management](https://millionrounds.com/fund/ra-capital-management) 23
- [Janus Henderson Investors](https://millionrounds.com/fund/janus-henderson-investors) 20
- [Cormorant Asset Management](https://millionrounds.com/fund/cormorant-asset-management) 18
- [Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) 17
- [OrbiMed](https://millionrounds.com/fund/orbimed) 12
- [Adage Capital Management](https://millionrounds.com/fund/adage-capital-management) 11

**Pitching RTW Investments LLC?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as RTW Investments LLC. A count of rooms they were both in, not a relationship either has claimed.

[**RA Capital Management** Private equity **23** rounds together](https://millionrounds.com/fund/ra-capital-management)[**Janus Henderson Investors** Private equity **20** rounds together](https://millionrounds.com/fund/janus-henderson-investors)[**Cormorant Asset Management** Private equity **18** rounds together](https://millionrounds.com/fund/cormorant-asset-management)[**Perceptive Advisors** Asset manager **17** rounds together](https://millionrounds.com/fund/perceptive-advisors)[**OrbiMed** Private equity **12** rounds together](https://millionrounds.com/fund/orbimed)[**Adage Capital Management** Asset manager **11** rounds together](https://millionrounds.com/fund/adage-capital-management)[**TCG Crossover** VC firm **8** rounds together](https://millionrounds.com/fund/tcg-crossover)[**Samsara BioCapital** VC firm **7** rounds together](https://millionrounds.com/fund/samsara-biocapital)[**TCG** Private equity **7** rounds together](https://millionrounds.com/fund/tcg)[**Vivo Capital** Private equity **7** rounds together](https://millionrounds.com/fund/vivo-capital)[**Blue Owl** Asset manager **6** rounds together](https://millionrounds.com/fund/blue-owl)[**Fidelity** VC firm **6** rounds together](https://millionrounds.com/fund/fidelity)

## Recently backed

The latest companies RTW Investments LLC put money into.

[**Pyxis Oncology** $110M · Sept 2026](https://millionrounds.com/company/pyxis-oncology)[**MoonLake Immunotherapeutics** $200M · Jun 2026](https://millionrounds.com/company/moonlake-immunotherapeutics)[**Ocugen** $115M · May 2026](https://millionrounds.com/company/ocugen)[**Whitehawk Therapeutics** $88M · May 2026](https://millionrounds.com/company/whitehawk-therapeutics)[**Spyre Therapeutics** $403M · Apr 2026](https://millionrounds.com/company/spyre-therapeutics)[**ImageneBio** $30M · Apr 2026](https://millionrounds.com/company/imagenebio)

## Quick answers about RTW Investments LLC

### What does RTW Investments LLC invest in?

RTW Investments LLC invests most often at Series B and Venture (54% of the rounds on record), in sectors such as Internet, Ride Sharing and Business Development.

### How active is RTW Investments LLC?

87 investments on record, 33 of them in the last 12 months, and it led 2. The most recent was in Oct 2026.

### What has RTW Investments LLC invested in recently?

Its most recent investments on record: Zai Lab (Undisclosed round, Oct 2026), Pyxis Oncology (Undisclosed round, Sept 2026) and MoonLake Immunotherapeutics (Undisclosed round, Jun 2026).

### How big are RTW Investments LLC's cheques?

The median round it joins is $125M.

### Does RTW Investments LLC lead rounds?

Sometimes: it led 2 of its 87 investments on record (2%).

### Where does RTW Investments LLC invest?

Most of the companies it backs are in the United States (84%) and Switzerland (8%).

### Is RTW Investments LLC investing now?

Yes: it is actively investing, with 33 investments in the last 12 months.

### Who does RTW Investments LLC invest alongside?

Most often RA Capital Management (23 rounds together), Janus Henderson Investors (20 rounds together) and Cormorant Asset Management (18 rounds together).

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