# Polaris Partners: portfolio, investments and team

> Polaris Partners is a vc firm based in United States. 490 investments on record, 21 in the last 12 months, latest Oct 2026.

Source: https://millionrounds.com/fund/polaris-partners (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Polaris Partners

Last cheque observed Oct 2026; 490 cheques on record.

Email

Deploying now New fund $439M, Oct 2025 VC firm

Pre-seed Seed Series A Drug Genomics Cell Therapy

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Deploying now

**70%** of best year **21** **cheques in 12 months**, 490 on record

Since the last cheque **11** days **00** hrs **00** min **00** sec

Median round **$36M** Rounds led **6 of 490** Sole investor **45 rounds** Exits **55 from the portfolio** Mostly in **United States, 77%**

Pitch Polaris Partners

## Polaris Partners highlights

- 01 21 cheques in the last 12 months
- 02 Mostly Series B and Series A: 55% of its rounds
- 03 Sole investor in 45 rounds, median $6.4M
- 04 55 exits from the portfolio

## What they do

> We have collaborated with talented biotech and healthcare entrepreneurs as they build transformational companies From their own website

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** Not stated
- **Stages:** Pre-seed Seed Series A Series B Growth Pre-IPO
- **Sectors:** Drug Genomics Cell Therapy
- **Based in:** Boston, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **490 appearances**

- **2026** 17 rounds
- **Oct** **[Soufflé Therapeutics](https://millionrounds.com/company/souffle-therapeutics)** Series B · US · Google News search **$135M** With 16 others
- **Sept** **[updoc](https://millionrounds.com/company/updoc)** Grant · AU **$9.2M** With 4 others
- **Aug** **[Faro AI](https://millionrounds.com/company/faro-ai)** Series B · US **$37M** With 3 others
- **Jun** **[Tavo Biotherapeutics](https://millionrounds.com/company/tavo-biotherapeutics)** Series A · Ventureburn **$17M** With 3 others
- **Jun** **[Triveni Bio](https://millionrounds.com/company/triveni-bio)** Series C · US **$65M** With 4 others
- **Jun** **[Leyden Labs](https://millionrounds.com/company/leyden-labs)** Venture · NL **$45M** With 2 others
- **Jun** **[Engine Biosciences](https://millionrounds.com/company/engine-biosciences)** Venture · SG **Undisclosed** With 2 others
- **May** **[Whisker Labs](https://millionrounds.com/company/whisker-labs)** Series D · US **$6.6M** With 2 others
- **Mar** **[Crossbow Therapeutics](https://millionrounds.com/company/crossbow-therapeutics)** Series B · US **$77M** With 1 other
- **Mar** **[Tropic Biosciences](https://millionrounds.com/company/tropic-biosciences)** Series C · GB **$105M** With 4 others
- **Jan** **[Primmune Therapeutics](https://millionrounds.com/company/primmune-therapeutics)** Series B · US · Bioqube Ventures **$8.6M** With 3 others
- **Jan** **[EpiBiologics](https://millionrounds.com/company/epibiologics)** Series B · US · Avego Management **$107M** With 11 others
- **Jan** **[Mesodyne](https://millionrounds.com/company/mesodyne)** Venture · US **Undisclosed** With 4 others
- **Jan** **[TRex Bio](https://millionrounds.com/company/trex-bio)** Venture · US **$50M** With 3 others
- **Jan** **[Primmune Therapeutics](https://millionrounds.com/company/primmune-therapeutics)** Series B · US **$23M** With 1 other
- **Jan** **[Muna Therapeutics](https://millionrounds.com/company/muna-therapeutics)** Grant · DK **$1.0M** With 3 others
- **Jan** **[BarkBox](https://millionrounds.com/company/barkbox)** Debt · US **$35M** With 5 others
- **2025** 18 rounds
- **Dec** **[Nomad Health](https://millionrounds.com/company/nomad-health)** Venture · US **$34M** With 7 others
- **Nov** **[Sovato](https://millionrounds.com/company/sovato)** Series B · US · TechStartups **$41M** With 6 others
- **Nov** **[Proof](https://millionrounds.com/company/proof)** Venture · US **$16M** With 5 others
- **Nov** **[Invivyd](https://millionrounds.com/company/invivyd)** US **$125M** With 5 others
- **Oct** **[Leyden Labs](https://millionrounds.com/company/leyden-labs)** Venture · NL **$35M** With 2 others
- **Oct** **[Indomo](https://millionrounds.com/company/indomo)** Seed · US **$25M** With 1 other
- **Oct** **[Zag Bio](https://millionrounds.com/company/zag-bio)** Series A · US · Firms' own news pages **$80M** With 9 others
- **Sept** **[Crossbow Therapeutics](https://millionrounds.com/company/crossbow-therapeutics)** Venture · US **$30M** With 1 other
- **Sept** **[Volastra Therapeutics](https://millionrounds.com/company/volastra-therapeutics)** Series A · US **$30M** With 4 others
- **Aug** **[Compass Therapeutics](https://millionrounds.com/company/compass-therapeutics)** US **$120M** With 4 others
- **Aug** **[Cirrus Therapeutics](https://millionrounds.com/company/cirrus-therapeutics)** Seed · US **$11M** With 2 others
- **Jul** **[Auron Therapeutics](https://millionrounds.com/company/auron-therapeutics)** Venture · US **Undisclosed** With 5 others
- **Jun** **[Whisker Labs](https://millionrounds.com/company/whisker-labs)** Debt · US **$15M** With 2 others
- **May** **[Cohere Health](https://millionrounds.com/company/cohere-health)** Series C · US **$90M** With 4 others
- **Feb** **[Tectonic Therapeutic](https://millionrounds.com/company/tectonic-therapeutic)** US **$185M** With 2 others
- **Jan** **[Leyden Labs](https://millionrounds.com/company/leyden-labs)** NL · Silicon Canals **$70M** *Led*
- **Jan** **[FIRE1](https://millionrounds.com/company/fire1)** Series B · IE **$120M** With 5 others
- **Jan** **[Soufflé Therapeutics](https://millionrounds.com/company/souffle-therapeutics)** Series A · US **$200M** With 4 others
- **2024** 27 rounds
- **Dec** **[Noema Pharma](https://millionrounds.com/company/noema-pharma)** Series B · CH **$147M** With 3 others
- **Dec** **[Tausight](https://millionrounds.com/company/tausight)** Venture · US **Undisclosed** With 4 others
- **Nov** **[Falkonry](https://millionrounds.com/company/falkonry)** Venture · US **$3.4M** With 3 others
- **Nov** **[TRex Bio](https://millionrounds.com/company/trex-bio)** Series B · US · Avego Management **$84M** With 8 others
- **Nov** **[Alector](https://millionrounds.com/company/alector)** Debt · US **$50M** With 5 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **6 named**

AC **Alexandra Cantley** Managing Member of the General Partner i Filing they signed

AS **Amy Schulman** Managing Member of the General Partner i Filing they signed

BC **Brian Chee** Managing Member of the General Partner i Filing they signed

BY **Bryce Youngren** Managing Member of the General Partner i Filing they signed

DL **Daniel Lombard** Managing Member of the General Partner i Filing they signed

EM **Eileen McGuire** Managing Member of the General Partner i Filing they signed

We also hold **50** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## Exits from the portfolio

Companies it backed that were later bought or listed **55 in all**

**[Voysis](https://millionrounds.com/company/voysis)** Bought by [Apple](https://millionrounds.com/fund/apple) **Undisclosed** Apr 2020

**[Pointy](https://millionrounds.com/company/pointy)** Bought by [Google](https://millionrounds.com/fund/google-assistant-investments) **$163M** Jan 2020

**[Bitium](https://millionrounds.com/company/bitium)** Bought by [Google](https://millionrounds.com/fund/google-assistant-investments) **Undisclosed** Sept 2017

**[Sosh](https://millionrounds.com/company/sosh)** Bought by [Postmates](https://millionrounds.com/fund/postmates) **Undisclosed** Nov 2015

**[BlackArrow](https://millionrounds.com/company/blackarrow)** Bought by Cross Mediaworks **Undisclosed** Aug 2015

**[Phytel](https://millionrounds.com/company/phytel)** Bought by [Ibm](https://millionrounds.com/fund/ibm) **Undisclosed** Apr 2015

**[ReadyForZero](https://millionrounds.com/company/readyforzero)** Bought by Avant **Undisclosed** Mar 2015

**[NextCode Health](https://millionrounds.com/company/nextcode-health)** Bought by [WuXi PharmaTech (Cayman)](https://millionrounds.com/fund/wuxi-pharmatech-cayman) **$65M** Jan 2015

**[Sun Catalytix](https://millionrounds.com/company/sun-catalytix)** Bought by [Lockheed Martin](https://millionrounds.com/fund/lockheed-martin-ventures) **Undisclosed** Aug 2014

**[docTrackr](https://millionrounds.com/company/doctrackr)** Bought by [Intralinks](https://millionrounds.com/fund/intralinks) **$10M** Apr 2014

**[BalconyTV](https://millionrounds.com/company/balconytv)** Bought by The Orchard **Undisclosed** Mar 2014

**[ShoeDazzle](https://millionrounds.com/company/shoedazzle)** Bought by JustFab **Undisclosed** Aug 2013

**[Spindle](https://millionrounds.com/company/spindle)** Bought by [Twitter](https://millionrounds.com/fund/twitter) **Undisclosed** Jun 2013

**[Aepona](https://millionrounds.com/company/aepona)** Bought by [Intel](https://millionrounds.com/fund/intel) **$130M** Apr 2013

**[Lascaux Co.](https://millionrounds.com/company/lascaux-co)** Bought by [Etsy](https://millionrounds.com/fund/etsy) **Undisclosed** Jan 2013

**[Formspring](https://millionrounds.com/company/formspring)** Bought by Spring.me **Undisclosed** Jan 2013

**[BridgePoint Medical](https://millionrounds.com/company/bridgepoint-medical)** Bought by [Boston Scientific](https://millionrounds.com/fund/boston-scientific) **Undisclosed** Sept 2012

**[Seamless Receipts](https://millionrounds.com/company/seamless-receipts)** Bought by Sailthru **Undisclosed** Jun 2012

**[Ascend Health](https://millionrounds.com/company/ascend-health)** Bought by [Universal Health Services](https://millionrounds.com/fund/universal-health-services) **Undisclosed** Jun 2012

**[Ember](https://millionrounds.com/company/ember)** Bought by Silicon Laboratories **$72M** May 2012

The latest 20 here. An exit counts when it came after the firm's first round in the company. From historical deal records.

New fund on file

**$439M**

raised in Oct 2025

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Pre-seed Seed Series A

Median round joined **$36M** the round, not its cheque Alone, median **$6.4M**

Led 6 of 490 rounds **1%**

- **Sole investor:** 45 rounds
- **Last cheque:** Oct 2026
- **Exits:** 55 from the portfolio

Rounds by stage said on their site

- Series B said *127*
- Series A said *112*
- Series C *76*
- Venture *72*
- Series D *25*
- Seed said *21*
- Pre-seed said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) 34
- [Flagship Pioneering, LLC](https://millionrounds.com/fund/flagship-pioneering-llc) 26
- [Lux Capital](https://millionrounds.com/fund/lux-capital) 22
- [Google Ventures](https://millionrounds.com/fund/gv) 21
- [Intersouth Partners](https://millionrounds.com/fund/intersouth-partners) 21
- [General Catalyst](https://millionrounds.com/fund/general-catalyst) 19

**Pitching Polaris Partners?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as Polaris Partners. A count of rooms they were both in, not a relationship either has claimed.

[**ARCH Venture Partners** VC firm **34** rounds together](https://millionrounds.com/fund/arch-venture-partners)[**Flagship Pioneering, LLC** VC firm **26** rounds together](https://millionrounds.com/fund/flagship-pioneering-llc)[**Lux Capital** VC firm **22** rounds together](https://millionrounds.com/fund/lux-capital)[**Google Ventures** Corporate VC **21** rounds together](https://millionrounds.com/fund/gv)[**Intersouth Partners** VC firm **21** rounds together](https://millionrounds.com/fund/intersouth-partners)[**General Catalyst** VC firm **19** rounds together](https://millionrounds.com/fund/general-catalyst)[**Venrock** VC firm **19** rounds together](https://millionrounds.com/fund/venrock)[**Atlas Venture** VC firm **18** rounds together](https://millionrounds.com/fund/atlas-venture)[**New Enterprise Associates** VC firm **16** rounds together](https://millionrounds.com/fund/new-enterprise-associates)[**OrbiMed** Private equity **16** rounds together](https://millionrounds.com/fund/orbimed)[**North Bridge Venture Partners & Growth Equity** VC firm **15** rounds together](https://millionrounds.com/fund/north-bridge-venture-partners-and-growth-equity)[**RRE Ventures** VC firm **13** rounds together](https://millionrounds.com/fund/rre-ventures)

## Recently backed

The latest companies Polaris Partners put money into.

[**updoc** $9.2M · Sept 2026](https://millionrounds.com/company/updoc)[**Tavo Biotherapeutics** $17M · Jun 2026](https://millionrounds.com/company/tavo-biotherapeutics)[**Triveni Bio** $65M · Jun 2026](https://millionrounds.com/company/triveni-bio)[**Leyden Labs** $45M · Jun 2026](https://millionrounds.com/company/leyden-labs)[**Engine Biosciences** Jun 2026](https://millionrounds.com/company/engine-biosciences)[**Whisker Labs** $6.6M · May 2026](https://millionrounds.com/company/whisker-labs)

## Quick answers about Polaris Partners

### What does Polaris Partners invest in?

Polaris Partners invests most often at Series B and Series A (55% of the rounds on record), in sectors such as Drug, Genomics and Cell Therapy.

### How active is Polaris Partners?

490 investments on record, 21 of them in the last 12 months, and it led 6. The most recent was in Oct 2026.

### What has Polaris Partners invested in recently?

Its most recent investments on record: Soufflé Therapeutics (Series B, Oct 2026), updoc (Grant, Sept 2026) and Faro AI (Series B, Aug 2026).

### How big are Polaris Partners's cheques?

The median round it joins is $36M.

### Does Polaris Partners lead rounds?

Sometimes: it led 6 of its 490 investments on record (1%).

### Where does Polaris Partners invest?

Most of the companies it backs are in the United States (77%) and the Netherlands (8%).

### Is Polaris Partners investing now?

Yes: it is actively investing, with 21 investments in the last 12 months.

### Who does Polaris Partners invest alongside?

Most often ARCH Venture Partners (34 rounds together), Flagship Pioneering, LLC (26 rounds together) and Lux Capital (22 rounds together).

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