# One North Carolina Small Business Program: portfolio, investments and team

> One North Carolina Small Business Program is an investment firm. 43 investments on record, 4 in the last 12 months, latest Sept 2026.

Source: https://millionrounds.com/fund/one-north-carolina-small-business-program (Millionrounds; every figure on the page links to its filing or article)

[Investor](https://millionrounds.com/investors)

# One North Carolina Small Business Program

Last cheque observed Sep 2026; 43 cheques on record.

Deploying now Investment firm

Grant Venture Debt Health Care Biotechnology

Deploying now

**50%** of best year **4** **cheques in 12 months**, 43 on record

Since the last cheque **55** days **00** hrs **00** min **00** sec

Median round **$75K** Rounds led **0 of 43** Sole investor **6 rounds** Mostly in **United States, 97%**

Pitch One North Carolina Small Business Program

## One North Carolina Small Business Program highlights

- 01 4 cheques in the last 12 months
- 02 Mostly Grant and Venture: 91% of its rounds
- 03 Sole investor in 6 rounds, median $188K

## What they do

- **Type:** Investment firm (from a list, unverified)
- **Cheque size:** Not stated
- **Sectors:** Health Care Biotechnology
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **43 appearances**

- **2026** 4 rounds
- **Sept** **[Perfusio](https://millionrounds.com/company/perfusio)** Grant · US **$75K** With 1 other
- **Sept** **[Reselute](https://millionrounds.com/company/reselute)** Grant · US **$75K** With 1 other
- **Sept** **[GreenLifeTech Corporation](https://millionrounds.com/company/greenlifetech-corporation)** Grant · US **$3K** Sole investor
- **Feb** **[AxNano](https://millionrounds.com/company/axnano)** Venture · US **Undisclosed** With 2 others
- **2025** 1 round
- **Jun** **[Reselute](https://millionrounds.com/company/reselute)** Seed · US **$1.8M** With 1 other
- **2024** 7 rounds
- **Oct** **[EydisBio](https://millionrounds.com/company/eydisbio)** Grant · US **$500K** With 2 others
- **Jul** **[EpiCypher](https://millionrounds.com/company/epicypher)** Venture · US **$3.3M** Sole investor
- **May** **[Voxel Innovations](https://millionrounds.com/company/voxel-innovations)** Venture · US **$4.2M** With 1 other
- **Apr** **[Selsym Biotech](https://millionrounds.com/company/selsym-biotech)** Grant · US **$3.0M** With 1 other
- **Feb** **[Phase](https://millionrounds.com/company/phase)** Grant · DE **$1.8M** With 2 others
- **Jan** **[Mimetics](https://millionrounds.com/company/mimetics)** Grant · US **$178K** With 2 others
- **Jan** **[Coprata](https://millionrounds.com/company/coprata)** Venture · US **Undisclosed** With 4 others
- **2023** 9 rounds
- **Dec** **[Susteon](https://millionrounds.com/company/susteon)** Grant · US **$200K** With 2 others
- **Sept** **[Smart Girls HQ](https://millionrounds.com/company/smart-girls-hq)** Venture · US **Undisclosed** With 2 others
- **May** **[OpiAID](https://millionrounds.com/company/opiaid)** Grant · US **$2.8M** Sole investor
- **May** **[Geometric Data Analytics](https://millionrounds.com/company/geometric-data-analytics)** Grant · US **$200K** With 2 others
- **May** **[QATCH Technologies](https://millionrounds.com/company/qatch-technologies)** Debt · US **$250K** With 2 others
- **May** **[Pulvinar Neuro](https://millionrounds.com/company/pulvinar-neuro)** Grant · US **$3.1M** With 1 other
- **Mar** **[BioMojo](https://millionrounds.com/company/biomojo)** Grant · US **$300K** Sole investor
- **Feb** **[Tellus Therapeutics](https://millionrounds.com/company/tellus-therapeutics)** Venture · US **$16M** With 2 others
- **Feb** **[Adámas Nano](https://millionrounds.com/company/adamas-nano)** Grant · US **$1.6M** With 1 other
- **2022** 16 rounds
- **Dec** **[Plakous Therapeutics](https://millionrounds.com/company/plakous-therapeutics)** Grant · US **$10K** With 1 other
- **Dec** **[Lumedica](https://millionrounds.com/company/lumedica)** Debt · US **$625K** With 2 others
- **Sept** **[ColoWrap](https://millionrounds.com/company/colowrap)** Grant · US **$75K** With 1 other
- **Sept** **[PHAXTEC](https://millionrounds.com/company/phaxtec)** Grant · US **$75K** With 1 other
- **Sept** **[GreenLifeTech Corporation](https://millionrounds.com/company/greenlifetech-corporation)** Grant · US **$49K** Sole investor
- **Sept** **[Proximal](https://millionrounds.com/company/proximal)** Grant · US **$75K** With 1 other
- **Sept** **[Drive Therapeutics](https://millionrounds.com/company/drive-therapeutics)** Grant · US **$75K** With 2 others
- **Sept** **[Oncurie](https://millionrounds.com/company/oncurie)** Grant · US **$75K** With 1 other
- **Sept** **[Quantworks](https://millionrounds.com/company/quantworks)** Grant · US **$75K** With 1 other
- **Sept** **[Minerva Lithium](https://millionrounds.com/company/minerva-lithium)** Grant · US **$75K** With 1 other
- **Sept** **[Advanced Materials Manufacturing](https://millionrounds.com/company/advanced-materials-manufacturing)** Grant · US **$75K** Sole investor
- **Sept** **[Gradient Medical](https://millionrounds.com/company/gradient-medical)** Grant · US **$75K** With 1 other
- **Sept** **[Secmation](https://millionrounds.com/company/secmation)** Grant · US **$59K** With 1 other
- **Sept** **[Telli Technologies](https://millionrounds.com/company/telli-technologies)** Grant · US **$75K** With 1 other
- **Sept** **[Third Floor Materials](https://millionrounds.com/company/third-floor-materials)** Grant · US **$37K** With 1 other
- **Sept** **[Isolere Bio](https://millionrounds.com/company/isolere-bio)** Grant · US **$75K** With 3 others
- **2021** 5 rounds
- **Jul** **[SinnovaTek](https://millionrounds.com/company/sinnovatek)** Seed · US **$5.0M** With 1 other
- **Feb** **[BENANOVA](https://millionrounds.com/company/benanova)** Grant **$75K** With 1 other
- **Feb** **[Onda Vision Technologies](https://millionrounds.com/company/onda-vision-technologies)** Grant **$39K** With 1 other

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The cheque

Grant Venture Debt

Median round joined **$75K** the round, not its cheque Alone, median **$188K**

Led 0 of 43 rounds **0%**

- **Sole investor:** 6 rounds
- **Last cheque:** Sept 2026

Rounds by stage said on their site

- Grant *33*
- Venture *6*
- Debt *2*
- Seed *2*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [National Science Foundation](https://millionrounds.com/fund/nsf-small-business-innovation-research-small-business-techno) 25
- [North Carolina Biotechnology Center](https://millionrounds.com/fund/north-carolina-bio) 8
- [National Institutes of Health](https://millionrounds.com/fund/national-institutes-of-health) 5
- [US Department of Energy](https://millionrounds.com/fund/u-s-department-of-energy) 4
- [NC IDEA](https://millionrounds.com/fund/nc-idea) 2
- [Triangle Tweener Fund](https://millionrounds.com/fund/triangle-tweener-fund) 2

**Pitching One North Carolina Small Business Program?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

Add to your CRM *→*

## Who they invest alongside

The investors most often in the same rounds as One North Carolina Small Business Program. A count of rooms they were both in, not a relationship either has claimed.

[**National Science Foundation** Government **25** rounds together](https://millionrounds.com/fund/nsf-small-business-innovation-research-small-business-techno)[**North Carolina Biotechnology Center** Government **8** rounds together](https://millionrounds.com/fund/north-carolina-bio)[**National Institutes of Health** Government **5** rounds together](https://millionrounds.com/fund/national-institutes-of-health)[**US Department of Energy** Government **4** rounds together](https://millionrounds.com/fund/u-s-department-of-energy)[**NC IDEA** VC firm **2** rounds together](https://millionrounds.com/fund/nc-idea)[**Triangle Tweener Fund** VC firm **2** rounds together](https://millionrounds.com/fund/triangle-tweener-fund)

## Recently backed

The latest companies One North Carolina Small Business Program put money into.

[**Perfusio** $75K · Sept 2026](https://millionrounds.com/company/perfusio)[**Reselute** $75K · Sept 2026](https://millionrounds.com/company/reselute)[**GreenLifeTech Corporation** $3K · Sept 2026](https://millionrounds.com/company/greenlifetech-corporation)[**AxNano** Feb 2026](https://millionrounds.com/company/axnano)[**EydisBio** $500K · Oct 2024](https://millionrounds.com/company/eydisbio)[**Voxel Innovations** $4.2M · May 2024](https://millionrounds.com/company/voxel-innovations)

## Quick answers about One North Carolina Small Business Program

### What does One North Carolina Small Business Program invest in?

One North Carolina Small Business Program invests most often at Grant and Venture (91% of the rounds on record), in sectors such as Health Care and Biotechnology.

### How active is One North Carolina Small Business Program?

43 investments on record, 4 of them in the last 12 months. The most recent was in Sept 2026.

### What has One North Carolina Small Business Program invested in recently?

Its most recent investments on record: Perfusio (Grant, Sept 2026), Reselute (Grant, Sept 2026) and GreenLifeTech Corporation (Grant, Sept 2026).

### How big are One North Carolina Small Business Program's cheques?

The median round it joins is $75K.

### Does One North Carolina Small Business Program lead rounds?

Rarely, if at all: none of its 43 investments on record names it as the lead.

### Where does One North Carolina Small Business Program invest?

Most of the companies it backs are in the United States (97%).

### Is One North Carolina Small Business Program investing now?

Yes: it is actively investing, with 4 investments in the last 12 months.

### Who does One North Carolina Small Business Program invest alongside?

Most often National Science Foundation (25 rounds together), North Carolina Biotechnology Center (8 rounds together) and National Institutes of Health (5 rounds together).

## Raising now?

Find the investors who back rounds like yours, and keep every conversation on one fundraising board.

Find similar investorsOpen your CRM

Built from the rounds we watched, its filings and its own website, refreshed every night. [How we count](https://millionrounds.com/methodology) · [Report a correction](https://millionrounds.com/corrections?slug=one-north-carolina-small-business-program) · [Is this your firm? Claim it](https://millionrounds.com/claim?org=one-north-carolina-small-business-program)