# Omega Funds: portfolio, investments and team

> Omega Funds is a vc firm based in United States. 104 investments on record, 17 in the last 12 months, latest Sept 2026.

Source: https://millionrounds.com/fund/omega-funds (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Omega Funds

Last cheque observed Sep 2026; 104 cheques on record.

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Deploying now New fund $580M, Apr 2025 VC firm

Buyout Growth Pre-seed Oncology Immunology Rare_diseases

Follow Omega Funds and see its new cheques in your feed. [Start following](https://millionrounds.com/login?join=1&why=follow&next=%2Ffund%2Fomega-funds)

Deploying now

**89%** of best year **17** **cheques in 12 months**, 104 on record

Since the last cheque **38** days **00** hrs **00** min **00** sec

Median round **$88M** Rounds led **8 of 104** Sole investor **5 rounds** Exits **1 from the portfolio** Mostly in **United States, 83%**

Pitch Omega Funds

## Omega Funds highlights

- 01 17 cheques in the last 12 months
- 02 Mostly Series A and Series B: 63% of its rounds
- 03 Sole investor in 5 rounds, median $2.6M
- 04 1 exits from the portfolio

## What they do

> We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas, including oncology, immunology, rare diseases, precision medicine and others. From their own website

- **Type:** VC firm
- **Cheque size:** Not stated
- **Stages:** Buyout Growth Pre-seed Seed Series A Series B
- **Sectors:** Oncology Immunology Rare_diseases
- **Based in:** Boston, United States
- **Cold pitches:** Not accepted

## The record

Every round we can evidence, newest first **104 appearances**

- **2026** 14 rounds
- **Sept** **[Anaconda Biomed](https://millionrounds.com/company/anaconda-biomed)** Series C · ES · Asabys **$56M** *Led*
- **Sept** **[Beta Bionics](https://millionrounds.com/company/beta-bionics)** US **$173M** With 3 others
- **Aug** **[Vaderis Therapeutics](https://millionrounds.com/company/vaderis-therapeutics)** Series B · CH · Firms' own news pages **$152M** With 8 others
- **May** **[Editas Medicine](https://millionrounds.com/company/editas-medicine)** US **$125M** With 3 others
- **May** **[Sana Biotechnology](https://millionrounds.com/company/sana-biotechnology)** US **$69M** With 4 others
- **Apr** **[Trevi Therapeutics](https://millionrounds.com/company/trevi-therapeutics)** US **$173M** With 3 others
- **Apr** **[Spruce Biosciences](https://millionrounds.com/company/spruce-biosciences)** US **$60M** With 2 others
- **Feb** **[Alveus Therapeutics Inc.](https://millionrounds.com/company/alveus-therapeutics-inc)** Series A · US · Seroba Life Sciences **$197M** *Led*
- **Feb** **[Beam Therapeutics](https://millionrounds.com/company/beam-therapeutics)** Debt · US **$100M** With 5 others
- **Jan** **[Alveus Therapeutics](https://millionrounds.com/company/alveus-therapeutics)** Series A · US · Avego Management **$160M** *Led*
- **Jan** **[Spruce Biosciences](https://millionrounds.com/company/spruce-biosciences)** Venture · US **Undisclosed** With 3 others
- **Jan** **[Alumis](https://millionrounds.com/company/alumis)** US **$345M** With 6 others
- **Jan** **[Caldera Therapeutics](https://millionrounds.com/company/caldera-therapeutics)** Series A · US **$38M** With 4 others
- **Jan** **[Spiro Medical](https://millionrounds.com/company/spiro-medical)** Series A · US **$67M** With 4 others
- **2025** 14 rounds
- **Dec** **[Kestra Medical Technologies, Inc.](https://millionrounds.com/company/kestra-medical-technologies-inc)** US **$138M** With 3 others
- **Dec** **[FoRx Therapeutics](https://millionrounds.com/company/forx-therapeutics)** Series A · CH **$50M** With 1 other
- **Dec** **[Protego Biopharma](https://millionrounds.com/company/protego-biopharma)** Series B · US · Firms' own news pages **$130M** With 9 others
- **Sept** **[NRG Therapeutics](https://millionrounds.com/company/nrg-therapeutics)** Series B · GB · Firms' own news pages **$68M** With 6 others
- **Jul** **[ARTBIO](https://millionrounds.com/company/artbio)** Series B · US **$132M** With 1 other
- **Jun** **[Trevi Therapeutics](https://millionrounds.com/company/trevi-therapeutics)** US **$115M** With 3 others
- **May** **[Ousia Pharma](https://millionrounds.com/company/ousia-pharma)** Venture · DK **Undisclosed** With 1 other
- **May** **[Senti Biosciences](https://millionrounds.com/company/senti-biosciences)** Grant · US **$1.0M** With 4 others
- **May** **[Antares Therapeutics](https://millionrounds.com/company/antares-therapeutics)** Series A · US **$177M** With 2 others
- **Apr** **[Hydrocision](https://millionrounds.com/company/hydrocision)** Venture · US **$2.5M** Sole investor
- **Mar** **[Nuvation Bio](https://millionrounds.com/company/nuvation-bio)** Debt · US **$150M** With 3 others
- **Mar** **[Callio Therapeutics](https://millionrounds.com/company/callio-therapeutics)** Series A · US **$187M** With 3 others
- **Jan** **[Windward Bio](https://millionrounds.com/company/windward-bio)** Series A · CH **$200M** With 4 others
- **Jan** **[Alleviant Medical](https://millionrounds.com/company/alleviant-medical)** Venture · US · Vensana Capital **$90M** With 2 others
- **2024** 9 rounds
- **Nov** **[Beta Bionics](https://millionrounds.com/company/beta-bionics)** Series E · US **$60M** With 4 others
- **Nov** **[Replimune Group](https://millionrounds.com/company/replimune-group)** US **$140M** With 5 others
- **Aug** **[XII Medical](https://millionrounds.com/company/xii-medical)** Series B · US **$45M** With 1 other
- **Jul** **[Scorpion Therapeutics](https://millionrounds.com/company/scorpion-therapeutics)** Series C · US **$150M** With 4 others
- **Jul** **[Vanqua Bio](https://millionrounds.com/company/vanqua-bio)** Venture · US **$45M** With 3 others
- **Jul** **[CatalYm](https://millionrounds.com/company/catalym)** Series D · DE **$150M** With 3 others
- **Jun** **[Marea Therapeutics](https://millionrounds.com/company/marea-therapeutics)** Series B · US **$190M** With 3 others
- **May** **[Bbot](https://millionrounds.com/company/bbot)** Venture · US **$200M** With 4 others
- **Apr** **[Endeavor BioMedicines](https://millionrounds.com/company/endeavor-biomedicines)** Series C · US **$133M** With 2 others
- **2023** 8 rounds
- **Nov** **[Alpine Immune Sciences](https://millionrounds.com/company/alpine-immune-sciences)** US **$150M** With 4 others
- **Nov** **[Eyebiotech](https://millionrounds.com/company/eyebiotech)** Series A · US **$65M** With 4 others
- **Jul** **[Gossamer Bio](https://millionrounds.com/company/gossamer-bio)** US **$212M** With 5 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **9 named**

AR **Alexandra Rankel Pearsall** Chief Financial Officer i Form ADV

AP **Anne-Mari Paster** Director i Filing they signed

CP **Claudio Pier Antonio Nessi** Manager & Member i Form ADV

FL **Francesco Luigi Draetta** Manager & Member i Form ADV

KB **Kevin Brennan** A Director of the general partner of the General Partner i Filing they signed

ME **Mark Emerson Russell** Chief Compliance Officer i Form ADV

O(**Otello (nmn) Stampacchia** A Director of the general partner of the General Partner i Filing they signed

RL **Richard Lim** Director i Filing they signed

SA **Sharon Alvarez** A Director of the general partner of the General Partner i Filing they signed

We also hold **16** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$1.7B** assets it manages Oct 2026

**Registered** investment adviser full reporting to the SEC

- **Legal name:** Omega Fund Management, LLC
- **SEC number:** CRD 157753

Funds on its Form ADV

**8** private funds, **$694M** in gross assets · filed Mar 2024

- Omega Fund VII, L.P. *Private equity* 87 investors $324M
- Omega Fund VI, L.P. *Private equity* 45 investors $268M
- Omega Fund V, L.P. *Private equity* 34 investors $68M
- Omega Fund IV, L.P. *Private equity* 37 investors $29M
- NET Assets of Omega Fund III, L.P. *Private equity* 15 investors $3.1M
- Omega Fund II, L.P. *Private equity* 6 investors $1.7M
- Life Sciences Holdings SPV I Fund, L.P. *Private equity* 1 investor $190K
- Omega Fund VIII, L.P. *Private equity* 42 investors -

## What they claim to have backed

From their own portfolio page (on their website)

**0** of 4 we have independently watched raise

Omega Fund V S3 Show + Tell Sscfundservices

Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.

## Exits from the portfolio

Companies it backed that were later bought or listed **1 in all**

**[Santaris Pharma](https://millionrounds.com/company/santaris-pharma)** Bought by Roche **$450M** Aug 2014

An exit counts when it came after the firm's first round in the company. From historical deal records.

New fund on file

**$580M**

raised in Apr 2025

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Buyout Growth Pre-seed

Median round joined **$88M** the round, not its cheque Alone, median **$2.6M**

Led 8 of 104 rounds **8%**

- **Sole investor:** 5 rounds
- **Last cheque:** Sept 2026
- **Exits:** 1 from the portfolio

Rounds by stage said on their site

- Series A said *25*
- Series B said *25*
- Series C *14*
- Venture *13*
- Series D *3*
- Buyout said *-*
- Growth said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [Atlas Venture](https://millionrounds.com/fund/atlas-venture) 10
- [Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) 10
- [Cormorant Asset Management](https://millionrounds.com/fund/cormorant-asset-management) 9
- [OrbiMed](https://millionrounds.com/fund/orbimed) 9
- [Polaris Partners](https://millionrounds.com/fund/polaris-partners) 8
- [Wellington Management](https://millionrounds.com/fund/wellington-management) 8

**Pitching Omega Funds?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as Omega Funds. A count of rooms they were both in, not a relationship either has claimed.

[**Atlas Venture** VC firm **10** rounds together](https://millionrounds.com/fund/atlas-venture)[**Perceptive Advisors** Asset manager **10** rounds together](https://millionrounds.com/fund/perceptive-advisors)[**Cormorant Asset Management** Private equity **9** rounds together](https://millionrounds.com/fund/cormorant-asset-management)[**OrbiMed** Private equity **9** rounds together](https://millionrounds.com/fund/orbimed)[**Polaris Partners** VC firm **8** rounds together](https://millionrounds.com/fund/polaris-partners)[**Wellington Management** VC firm **8** rounds together](https://millionrounds.com/fund/wellington-management)[**EcoR1 Capital** Private equity **7** rounds together](https://millionrounds.com/fund/ecor1-capital)[**Forbion Capital Partners** Private equity **7** rounds together](https://millionrounds.com/fund/forbion-capital-partners)[**ARCH Venture Partners** VC firm **6** rounds together](https://millionrounds.com/fund/arch-venture-partners)[**Fidelity** VC firm **6** rounds together](https://millionrounds.com/fund/fidelity)[**Google Ventures** Corporate VC **6** rounds together](https://millionrounds.com/fund/gv)[**Redmile Group** VC firm **6** rounds together](https://millionrounds.com/fund/redmile-group)

## Recently backed

The latest companies Omega Funds put money into.

[**Anaconda Biomed** $56M · Sept 2026](https://millionrounds.com/company/anaconda-biomed)[**Beta Bionics** $173M · Sept 2026](https://millionrounds.com/company/beta-bionics)[**Editas Medicine** $125M · May 2026](https://millionrounds.com/company/editas-medicine)[**Sana Biotechnology** $69M · May 2026](https://millionrounds.com/company/sana-biotechnology)[**Trevi Therapeutics** $173M · Apr 2026](https://millionrounds.com/company/trevi-therapeutics)[**Alveus Therapeutics Inc.** $197M · Feb 2026](https://millionrounds.com/company/alveus-therapeutics-inc)

## Mentioned on podcasts

Episodes that name Omega Funds in their description, not their title.

- [The Biotech Startups Podcast](https://millionrounds.com/podcasts/biotech-startups) 2 Jun 2025 · 37 min 🧬 Biotech Investing Unlocked: Mindset Shift, Risk, and Founder-First Lessons | Johnny Hu (Part 3/4) With [Johnny Hu](https://millionrounds.com/person/johnny-hu) Mentions [Menlo Ventures](https://millionrounds.com/fund/menlo-ventures)[Omega Funds](https://millionrounds.com/fund/omega-funds) Apple PodcastsShow page

## Quick answers about Omega Funds

### What does Omega Funds invest in?

Omega Funds invests most often at Series A and Series B (63% of the rounds on record), in sectors such as Oncology, Immunology and Rare_diseases.

### How active is Omega Funds?

104 investments on record, 17 of them in the last 12 months, and it led 8. The most recent was in Sept 2026.

### What has Omega Funds invested in recently?

Its most recent investments on record: Anaconda Biomed (Series C, Sept 2026), Beta Bionics (Undisclosed round, Sept 2026) and Vaderis Therapeutics (Series B, Aug 2026).

### How big are Omega Funds's cheques?

The median round it joins is $88M.

### Does Omega Funds lead rounds?

Sometimes: it led 8 of its 104 investments on record (8%).

### Where does Omega Funds invest?

Most of the companies it backs are in the United States (83%) and Switzerland (8%).

### Is Omega Funds investing now?

Yes: it is actively investing, with 17 investments in the last 12 months.

### Who does Omega Funds invest alongside?

Most often Atlas Venture (10 rounds together), Perceptive Advisors (10 rounds together) and Cormorant Asset Management (9 rounds together).

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