# Main Sequence Ventures: portfolio, investments and team

> Main Sequence Ventures is a vc firm based in Australia. 84 investments on record, 26 in the last 12 months, latest Sept 2026.

Source: https://millionrounds.com/fund/main-sequence (Millionrounds; every figure on the page links to its filing or article)

Australia · [Investor](https://millionrounds.com/investors)

# Main Sequence Ventures

Last cheque observed Sep 2026; 84 cheques on record.

Email

Deploying now VC firm

Pre-seed Seed Series A Space Climate Technology

Follow Main Sequence Ventures and see its new cheques in your feed. [Start following](https://millionrounds.com/login?join=1&why=follow&next=%2Ffund%2Fmain-sequence)

Deploying now

**87%** of best year **26** **cheques in 12 months**, 84 on record

Since the last cheque **38** days **00** hrs **00** min **00** sec

Median round **$13M** Cheque size, as they say **$250K – $20M** Rounds led **9 of 84** Sole investor **14 rounds** Mostly in **Australia, 92%**

Pitch Main Sequence Ventures

## Main Sequence Ventures highlights

- 01 26 cheques in the last 12 months
- 02 Mostly Venture and Series A: 56% of its rounds
- 03 Sole investor in 14 rounds, median $2.2M

## What they do

> a venture capital firm designed for deeptech From their own website

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** $250K – $20M as they say
- **Stages:** Pre-seed Seed Series A Series B Growth
- **Sectors:** Space Climate Technology
- **Based in:** Eveleigh, Australia
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **84 appearances**

- **2026** 21 rounds
- **Sept** **[Kinoxis Therapeutics](https://millionrounds.com/company/kinoxis-therapeutics)** AU · Startup Daily **$4.8M** *Led*
- **Sept** **[Amber Electric](https://millionrounds.com/company/amber-electric)** Series E · AU · TechStartups **$56M** With 9 others
- **Sept** **[Metacognition AI](https://millionrounds.com/company/metacognition-ai)** Pre-seed · AU · TechStartups **$10M** *Led*
- **Sept** **[Universal Quantum](https://millionrounds.com/company/universal-quantum)** Series A · GB · Tech.eu **$100M** With 18 others
- **Aug** **[Facet Amtech](https://millionrounds.com/company/facet-amtech)** Seed · AU **$2.2M** With 2 others
- **Jul** **[Emesent](https://millionrounds.com/company/emesent)** AU · Startup Daily **$15M** With 6 others
- **Jun** **[Number 8 bio](https://millionrounds.com/company/number-8-bio)** Grant · AU **$15K** With 1 other
- **May** **[Arkeus](https://millionrounds.com/company/arkeus)** Series A · AU · Firms' own news pages **$25M** With 6 others
- **May** **[Diraq](https://millionrounds.com/company/diraq)** Grant · AU **$38M** With 2 others
- **Apr** **[Aigentsphere](https://millionrounds.com/company/aigentsphere)** Seed · AU · Startup Daily **$4.0M** *Led*
- **Apr** **[Deteqt](https://millionrounds.com/company/deteqt)** Seed · AU · Startup Daily **$5.0M** *Led*
- **Apr** **[ULUU](https://millionrounds.com/company/uluu)** Grant · AU **$1.5M** With 2 others
- **Mar** **[Advanced Navigation](https://millionrounds.com/company/advanced-navigation)** Series C · AU · Startup Daily **$158M** With 4 others
- **Mar** **[MGA Thermal](https://millionrounds.com/company/mga-thermal)** Venture · AU · Startup Daily **$12M** With 3 others
- **Mar** **[Number 8 bio](https://millionrounds.com/company/number-8-bio)** Grant · AU **$834K** With 2 others
- **Mar** **[Cauldron Ferm](https://millionrounds.com/company/cauldron-ferm)** Series A · AU **$13M** With 3 others
- **Feb** **[Breaker](https://millionrounds.com/company/breaker)** Seed · AU · Startup Daily **$9.0M** With 2 others
- **Feb** **[Kasada](https://millionrounds.com/company/kasada)** Ventureburn **$20M** With 6 others
- **Feb** **[Diraq](https://millionrounds.com/company/diraq)** Venture · AU **$14M** With 1 other
- **Jan** **[Gilmour Space Technologies](https://millionrounds.com/company/gilmour-space-technologies)** Growth · AU · Startup Daily **$217M** With 9 others
- **Jan** **[Gilmour Space Technologies](https://millionrounds.com/company/gilmour-space-technologies)** Series E · AU **$146M** With 2 others
- **2025** 24 rounds
- **Dec** **[Kasada](https://millionrounds.com/company/kasada)** AU · Startup Daily **$20M** With 6 others
- **Dec** **[ULUU](https://millionrounds.com/company/uluu)** Grant · AU **$990K** With 2 others
- **Nov** **[Number 8 Bio](https://millionrounds.com/company/number-8-bio)** Series A · AU · Startup Daily **$11M** With 2 others
- **Nov** **[Sundrive Solar](https://millionrounds.com/company/sundrive-solar)** Grant · AU **$17M** With 2 others
- **Nov** **[The EVERY Company](https://millionrounds.com/company/the-every-company)** Series D · US **$55M** With 4 others
- **Oct** **[Uluu](https://millionrounds.com/company/uluu)** Series A · AU · Startup Daily **$16M** With 5 others
- **Oct** **[RainStick](https://millionrounds.com/company/rainstick)** Venture · CA **Undisclosed** With 2 others
- **Oct** **[Cauldron Ferm](https://millionrounds.com/company/cauldron-ferm)** Venture · AU **Undisclosed** With 3 others
- **Sept** **[Andromeda](https://millionrounds.com/company/andromeda)** Series A · AU · Startup Daily **$23M** With 8 others
- **Sept** **[Morse Micro](https://millionrounds.com/company/morse-micro)** Series C · AU **$58M** With 5 others
- **Sept** **[Andromeda Robotics](https://millionrounds.com/company/andromeda-robotics)** Series A · AU **$15M** With 3 others
- **Sept** **[Endua](https://millionrounds.com/company/endua)** Grant · AU **$20K** Sole investor
- **Jul** **[Diraq](https://millionrounds.com/company/diraq)** AU · Startup Daily **$15M** With 5 others
- **Jul** **[Arkeus](https://millionrounds.com/company/arkeus)** Grant · AU **$1.6M** Sole investor
- **Jul** **[v2food](https://millionrounds.com/company/v2food)** Venture · AU **$17M** With 3 others
- **May** **[Levur](https://millionrounds.com/company/levur)** Pre-seed · AU · Startup Daily **$1.2M** *Led*
- **Apr** **[QuintessenceLabs](https://millionrounds.com/company/quintessencelabs)** Venture · AU **$13M** With 2 others
- **Mar** **[DeteQt](https://millionrounds.com/company/deteqt)** Pre-seed · AU · Startup Daily **$750K** With 1 other
- **Mar** **[Breaker](https://millionrounds.com/company/breaker)** Pre-seed · AU · Startup Daily **$2.0M** *Led*

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

We hold **20** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## The cheque

Pre-seed Seed Series A

Median round joined **$13M** the round, not its cheque Alone, median **$2.2M**

Led 9 of 84 rounds **11%**

- **Said size:** $250K – $20M
- **Sole investor:** 14 rounds
- **Last cheque:** Sept 2026

Rounds by stage said on their site

- Venture *19*
- Series A said *16*
- Seed said *11*
- Grant *10*
- Series B said *6*
- Pre-seed said *-*
- Growth said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [In-Q-Tel](https://millionrounds.com/fund/iqt) 10
- [Startmate](https://millionrounds.com/fund/startmate) 9
- [Blackbird Ventures](https://millionrounds.com/fund/blackbird-ventures-2) 7
- [Possible Ventures](https://millionrounds.com/fund/possible-ventures) 7
- [Horizons Ventures](https://millionrounds.com/fund/horizons-ventures) 6
- [Uniseed Ventures](https://millionrounds.com/fund/uniseed) 5

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## Who they invest alongside

The investors most often in the same rounds as Main Sequence Ventures. A count of rooms they were both in, not a relationship either has claimed.

[**In-Q-Tel** Accelerator **10** rounds together](https://millionrounds.com/fund/iqt)[**Startmate** Accelerator **9** rounds together](https://millionrounds.com/fund/startmate)[**Blackbird Ventures** VC firm **7** rounds together](https://millionrounds.com/fund/blackbird-ventures-2)[**Possible Ventures** VC firm **7** rounds together](https://millionrounds.com/fund/possible-ventures)[**Horizons Ventures** VC firm **6** rounds together](https://millionrounds.com/fund/horizons-ventures)[**Uniseed Ventures** VC firm **5** rounds together](https://millionrounds.com/fund/uniseed)[**DCVC** VC firm **4** rounds together](https://millionrounds.com/fund/data-collective)[**Hostplus** Private equity **4** rounds together](https://millionrounds.com/fund/hostplus)[**iSeed** VC firm **4** rounds together](https://millionrounds.com/fund/iseed)[**Airtree Ventures** VC firm **3** rounds together](https://millionrounds.com/fund/airtree)[**Artesian VC** Asset manager **3** rounds together](https://millionrounds.com/fund/artesian)[**Chevron Technology Ventures** Corporate VC **3** rounds together](https://millionrounds.com/fund/chevron-technology-ventures)

## Recently backed

The latest companies Main Sequence Ventures put money into.

[**Kinoxis Therapeutics** $4.8M · Sept 2026](https://millionrounds.com/company/kinoxis-therapeutics)[**Amber Electric** $56M · Sept 2026](https://millionrounds.com/company/amber-electric)[**Universal Quantum** $100M · Sept 2026](https://millionrounds.com/company/universal-quantum)[**Facet Amtech** $2.2M · Aug 2026](https://millionrounds.com/company/facet-amtech)[**Emesent** $15M · Jul 2026](https://millionrounds.com/company/emesent)[**Number 8 bio** $15K · Jun 2026](https://millionrounds.com/company/number-8-bio)

## Mentioned on podcasts

Episodes that name Main Sequence Ventures in their description, not their title.

- [Startup 360](https://millionrounds.com/podcasts/startup-360) 15 May 2025 · 1h 1m A Husic eulogy, the problem with medtech funding, and Australia’s most psychedelic founder Mentions [Main Sequence Ventures](https://millionrounds.com/fund/main-sequence) Apple Podcasts

## Quick answers about Main Sequence Ventures

### What does Main Sequence Ventures invest in?

Main Sequence Ventures invests most often at Venture and Series A (56% of the rounds on record), in sectors such as Space, Climate and Technology.

### How active is Main Sequence Ventures?

84 investments on record, 26 of them in the last 12 months, and it led 9. The most recent was in Sept 2026.

### What has Main Sequence Ventures invested in recently?

Its most recent investments on record: Kinoxis Therapeutics (Sept 2026), Amber Electric (Series E, Sept 2026) and Metacognition AI (Pre-seed, Sept 2026).

### How big are Main Sequence Ventures's cheques?

The median round it joins is $13M. It says it writes cheques of $250K to $20M.

### Does Main Sequence Ventures lead rounds?

Sometimes: it led 9 of its 84 investments on record (11%).

### Where does Main Sequence Ventures invest?

Most of the companies it backs are in Australia (92%).

### Is Main Sequence Ventures investing now?

Yes: it is actively investing, with 26 investments in the last 12 months.

### Who does Main Sequence Ventures invest alongside?

Most often In-Q-Tel (10 rounds together), Startmate (9 rounds together) and Blackbird Ventures (7 rounds together).

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