# Catalio Capital Management: portfolio, investments and team

> Catalio Capital Management is a vc firm based in United States. 108 investments on record, 42 in the last 12 months, latest Oct 2026.

Source: https://millionrounds.com/fund/catalio-capital-management (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Catalio Capital Management

Last cheque observed Oct 2026; 108 cheques on record.

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Deploying now New fund $20M, Sept 2026 VC firm

Seed Series A Series B Healthcare Drugs Ai-enabled

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Deploying now

**93%** of best year **42** **cheques in 12 months**, 108 on record

Since the last cheque **8** days **00** hrs **00** min **00** sec

Median round **$73M** Cheque size, as they say **$100K – $5.0M** Rounds led **4 of 108** Sole investor **10 rounds** Mostly in **United States, 88%**

Pitch Catalio Capital Management

## Catalio Capital Management highlights

- 01 42 cheques in the last 12 months
- 02 Mostly Venture and Series B: 59% of its rounds
- 03 Sole investor in 10 rounds, median $20M

## What they do

> A New York based investment firm focused on the full lifecycle of innovative healthcare investing, across private, public and credit markets. From their own website

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** $100K – $5.0M as they say
- **Stages:** Seed Series A Series B Growth Pre-IPO
- **Sectors:** Healthcare Drugs Ai-enabled
- **Based in:** New York, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **108 appearances**

- **2026** 35 rounds
- **Oct** **[Star Therapeutics](https://millionrounds.com/company/star-therapeutics)** US · Pulse 2.0 **$200M** With 10 others
- **Oct** **[ZAP Surgical Systems](https://millionrounds.com/company/zap-surgical-systems)** Growth · US · AI Insider **$36M** *Led*
- **Sept** **[BigHat Biosciences](https://millionrounds.com/company/bighat-biosciences)** Series C · US · Kevin Moore **$75M** With 4 others
- **Sept** **[Basecamp Research](https://millionrounds.com/company/basecamp-research)** Series C · GB · Ventureburn **$140M** With 17 others
- **Sept** **[Stuut Technologies](https://millionrounds.com/company/stuut-technologies)** Series B · US · Ventureburn **$53M** *Led*
- **Sept** **[Evvy](https://millionrounds.com/company/evvy)** Series B · US · TechCrunch **$40M** *Led*
- **Sept** **[Enveda](https://millionrounds.com/company/enveda)** Series E · US **$311M** With 3 others
- **Sept** **[IAMBIC](https://millionrounds.com/company/iambic)** Debt · US **$66M** With 5 others
- **Sept** **[Avava](https://millionrounds.com/company/avava)** Venture · US **$30M** Sole investor
- **Sept** **[OpenEvidence](https://millionrounds.com/company/openevidence)** Series E · US **$250M** With 4 others
- **Aug** **[Georgiamune](https://millionrounds.com/company/georgiamune)** Series B · US **$93M** With 3 others
- **Jul** **[AdvanCell](https://millionrounds.com/company/advancell)** Series D · AU · QRM Capital **$315M** With 16 others
- **Jul** **[Claris Biotherapeutics](https://millionrounds.com/company/claris-biotherapeutics)** Series B · US **$118M** With 4 others
- **Jul** **[Cambrian Biopharma](https://millionrounds.com/company/cambrian-biopharma)** Venture · US **$124M** With 4 others
- **Jul** **[Leo Cancer Care](https://millionrounds.com/company/leo-cancer-care)** Series D · GB **$65M** With 2 others
- **Jul** **[Ratio Therapeutics](https://millionrounds.com/company/ratio-therapeutics)** Series C · US **$70M** With 1 other
- **Jun** **[Flourish](https://millionrounds.com/company/flourish)** Growth · US · Ventureburn **$500M** With 3 others
- **Jun** **[Parabilis Medicines](https://millionrounds.com/company/parabilis-medicines)** US **$75M** With 4 others
- **May** **[Thea](https://millionrounds.com/company/thea)** Pre-seed · US **$4.0M** With 3 others
- **May** **[9amHealth](https://millionrounds.com/company/9amhealth)** Series B · US **$26M** With 3 others
- **May** **[Cartography Biosciences](https://millionrounds.com/company/cartography-biosciences)** Venture · US **Undisclosed** With 4 others
- **May** **[ArriVent](https://millionrounds.com/company/arrivent)** US **$250M** With 4 others
- **May** **[Odyssey Therapeutics](https://millionrounds.com/company/odyssey-therapeutics)** US **$25M** With 4 others
- **Apr** **[Spiral Therapeutics](https://millionrounds.com/company/spiral-therapeutics)** Series B · US · LifeLink Ventures **$27M** With 1 other
- **Apr** **[Beacon Biosignals](https://millionrounds.com/company/beacon-biosignals)** Series B · US **$11M** With 3 others
- **Mar** **[Imperative Care, Inc.](https://millionrounds.com/company/imperative-care-inc)** US · Elevage Medical Technologies **$100M** With 6 others
- **Mar** **[Hyperfine](https://millionrounds.com/company/hyperfine)** Debt · US **$40M** With 1 other
- **Mar** **[Avava](https://millionrounds.com/company/avava)** Series D · US **$20M** Sole investor
- **Mar** **[Dianthus Therapeutics](https://millionrounds.com/company/dianthus-therapeutics)** US **$719M** With 3 others
- **Feb** **[Somethings](https://millionrounds.com/company/somethings)** Series A · US · AlleyWatch **$19M** *Led*
- **Feb** **[COMPASS Pathways](https://millionrounds.com/company/compass-pathways)** GB **$200M** With 4 others
- **Feb** **[ProSomnus Sleep Technologies](https://millionrounds.com/company/prosomnus-sleep-technologies)** Venture · US **$38M** Sole investor
- **Jan** **[Parabilis Medicines](https://millionrounds.com/company/parabilis-medicines)** Series F · US **$305M** With 4 others
- **Jan** **[PrognomiQ](https://millionrounds.com/company/prognomiq)** Venture · US **$12M** With 4 others
- **Jan** **[Lila Sciences](https://millionrounds.com/company/lila-sciences)** Grant · US **$671K** With 3 others
- **2025** 35 rounds
- **Dec** **[Sidera Bio](https://millionrounds.com/company/sidera-bio)** Series A · DK **$109M** With 3 others
- **Dec** **[Protara Therapeutics](https://millionrounds.com/company/protara-therapeutics)** US **$75M** With 2 others
- **Dec** **[Medra AI](https://millionrounds.com/company/medra-ai)** Series A · US **$52M** With 5 others
- **Nov** **[Beacon Biosignals](https://millionrounds.com/company/beacon-biosignals)** Series B · US **$86M** With 8 others
- **Nov** **[Freenome](https://millionrounds.com/company/freenome)** Venture · US **$75M** With 4 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **5 named**

GP **George Petrocheilos** Executive Officer i Filing they signed

GP **Georgios Petrocheilos** Manager and Member of the Manager i Filing they signed

OE **Olga Eduardovna Maltseva** Chief Compliance Officer and Head of Operations i Form ADV

RJ **R. Jacob Vogelstein** Manager and Member of the Manager i Filing they signed

RJ **Rachel Jacob Vogelstein** Manager and Member of Manager i Filing they signed

We also hold **79** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$2.2B** assets it manages Oct 2026

**Registered** investment adviser full reporting to the SEC

- **Legal name:** Catalio Capital Management, LP
- **SEC number:** CRD 310374

Funds on its Form ADV

**15** private funds, **$1.0B** in gross assets · filed Mar 2024

Venture **9** Private equity **3** Hedge **1**

- Catalio Nexus Fund III, L.P. *Private equity* 327 investors $365M
- Catalio Nexus Fund IV, L.P. *Private equity* 166 investors $191M
- Catalio Public Equities Master Fund, L.P. *Hedge* 59 investors $109M
- Catalio Nexus Fund II, L.P. *Private equity* 151 investors $88M
- Catalio Structured Opportunities Fund I L.P. *Private credit* 83 investors $55M
- Catalio Genesis Fund I, LLC *Venture* 54 investors $47M
- Catalio Genesis Fund II, LLC *Venture* 100 investors $43M
- Catalio Genesis Fund III, LLC *Venture* 77 investors $36M
- Catalio Structured Opportunities AIV I L.P. *Structured credit* 80 investors $31M
- Catalio Access Fund V, LLC *Venture* 60 investors $15M

And 5 more on the filing.

New fund on file

**$20M**

raised in Sept 2026

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Seed Series A Series B

Median round joined **$73M** the round, not its cheque Alone, median **$20M**

Led 4 of 108 rounds **4%**

- **Said size:** $100K – $5.0M
- **Sole investor:** 10 rounds
- **Last cheque:** Oct 2026

Rounds by stage said on their site

- Venture *26*
- Series B said *21*
- Series A said *17*
- Series D *11*
- Grant *5*
- Seed said *-*
- Growth said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [General Catalyst](https://millionrounds.com/fund/general-catalyst) 17
- [RA Capital Management](https://millionrounds.com/fund/ra-capital-management) 17
- [Alumni Ventures](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund) 10
- [Lux Capital](https://millionrounds.com/fund/lux-capital) 9
- [Andreessen Horowitz](https://millionrounds.com/fund/andreessen-horowitz) 8
- [Janus Henderson Investors](https://millionrounds.com/fund/janus-henderson-investors) 8

**Pitching Catalio Capital Management?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as Catalio Capital Management. A count of rooms they were both in, not a relationship either has claimed.

[**General Catalyst** VC firm **17** rounds together](https://millionrounds.com/fund/general-catalyst)[**RA Capital Management** Private equity **17** rounds together](https://millionrounds.com/fund/ra-capital-management)[**Alumni Ventures** VC firm **10** rounds together](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund)[**Lux Capital** VC firm **9** rounds together](https://millionrounds.com/fund/lux-capital)[**Andreessen Horowitz** VC firm **8** rounds together](https://millionrounds.com/fund/andreessen-horowitz)[**Janus Henderson Investors** Private equity **8** rounds together](https://millionrounds.com/fund/janus-henderson-investors)[**S32** VC firm **8** rounds together](https://millionrounds.com/fund/s32)[**8VC** VC firm **7** rounds together](https://millionrounds.com/fund/8vc)[**ARCH Venture Partners** VC firm **7** rounds together](https://millionrounds.com/fund/arch-venture-partners)[**Eli Lilly** Corporate VC **7** rounds together](https://millionrounds.com/fund/eli-lilly)[**Gaingels** Private equity **7** rounds together](https://millionrounds.com/fund/gaingels)[**Polaris Partners** VC firm **7** rounds together](https://millionrounds.com/fund/polaris-partners)

## Recently backed

The latest companies Catalio Capital Management put money into.

[**Star Therapeutics** $200M · Oct 2026](https://millionrounds.com/company/star-therapeutics)[**BigHat Biosciences** $75M · Sept 2026](https://millionrounds.com/company/bighat-biosciences)[**Basecamp Research** $140M · Sept 2026](https://millionrounds.com/company/basecamp-research)[**Evvy** $40M · Sept 2026](https://millionrounds.com/company/evvy)[**Enveda** $311M · Sept 2026](https://millionrounds.com/company/enveda)[**IAMBIC** $66M · Sept 2026](https://millionrounds.com/company/iambic)

## Quick answers about Catalio Capital Management

### What does Catalio Capital Management invest in?

Catalio Capital Management invests most often at Venture and Series B (59% of the rounds on record), in sectors such as Healthcare, Drugs and Ai-enabled.

### How active is Catalio Capital Management?

108 investments on record, 42 of them in the last 12 months, and it led 4. The most recent was in Oct 2026.

### What has Catalio Capital Management invested in recently?

Its most recent investments on record: Star Therapeutics (Undisclosed round, Oct 2026), ZAP Surgical Systems (Growth, Oct 2026) and BigHat Biosciences (Series C, Sept 2026).

### How big are Catalio Capital Management's cheques?

The median round it joins is $73M. It says it writes cheques of $100K to $5.0M.

### Does Catalio Capital Management lead rounds?

Sometimes: it led 4 of its 108 investments on record (4%).

### Where does Catalio Capital Management invest?

Most of the companies it backs are in the United States (88%) and the United Kingdom (8%).

### Is Catalio Capital Management investing now?

Yes: it is actively investing, with 42 investments in the last 12 months.

### Who does Catalio Capital Management invest alongside?

Most often General Catalyst (17 rounds together), RA Capital Management (17 rounds together) and Alumni Ventures (10 rounds together).

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