# Casdin Capital: portfolio, investments and team

> Casdin Capital is a vc firm based in United States. 104 investments on record, 8 in the last 12 months, latest Oct 2026.

Source: https://millionrounds.com/fund/casdin-capital (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Casdin Capital

Last cheque observed Oct 2026; 104 cheques on record.

Email

Deploying now New fund $234M, Nov 2021 VC firm

Seed Series A Series B Health Healthier Living Digital-health

Follow Casdin Capital and see its new cheques in your feed. [Start following](https://millionrounds.com/login?join=1&why=follow&next=%2Ffund%2Fcasdin-capital)

Deploying now

**50%** of best year **8** **cheques in 12 months**, 104 on record

Since the last cheque **6** days **00** hrs **00** min **00** sec

Median round **$65M** Cheque size, as they say **$100K – $5.0M** Rounds led **1 of 104** Sole investor **5 rounds** Exits **2 from the portfolio** Mostly in **United States, 90%**

Pitch Casdin Capital

## Casdin Capital highlights

- 01 8 cheques in the last 12 months
- 02 Mostly Series B and Series A: 69% of its rounds
- 03 Sole investor in 5 rounds, median $8.1M
- 04 2 exits from the portfolio

## What they do

> Filed 2 private fund offerings with the SEC, the most recent in 2021-11 From their own website

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** $100K – $5.0M as they say
- **Stages:** Seed Series A Series B Growth Pre-IPO
- **Sectors:** Health Healthier Living Digital-health
- **Based in:** New York, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **104 appearances**

- **2026** 6 rounds
- **Oct** **[Bolt Biotherapeutics](https://millionrounds.com/company/bolt-biotherapeutics)** US · Pulse 2.0 **$120M** With 11 others
- **Jun** **[City Therapeutics](https://millionrounds.com/company/city-therapeutics)** Series B · US · Ventureburn **$100M** With 8 others
- **Jun** **[4D Molecular Therapeutics](https://millionrounds.com/company/4d-molecular-therapeutics)** Debt · US **$200M** With 3 others
- **Apr** **[Revolution Medicines](https://millionrounds.com/company/revolution-medicines)** US **$1.5B** With 2 others
- **Jan** **[Apella](https://millionrounds.com/company/apella)** Series A · US · Vensana Capital **$80M** With 2 others
- **Jan** **[Foghorn Therapeutics](https://millionrounds.com/company/foghorn-therapeutics)** US **$50M** With 3 others
- **2025** 13 rounds
- **Dec** **[Contineum Therapeutics](https://millionrounds.com/company/contineum-therapeutics)** US **$99M** With 3 others
- **Nov** **[4D Molecular Therapeutics](https://millionrounds.com/company/4d-molecular-therapeutics)** US **$100M** With 2 others
- **Oct** **[Octave](https://millionrounds.com/company/octave)** Venture · US **Undisclosed** With 3 others
- **Aug** **[CANbridge Pharmaceuticals](https://millionrounds.com/company/canbridge-pharmaceuticals)** **$13M** With 3 others
- **Aug** **[Bbot](https://millionrounds.com/company/bbot)** US **$261M** With 3 others
- **Aug** **[Prime Medicine](https://millionrounds.com/company/prime-medicine)** US **$5.0M** With 4 others
- **Jul** **[Auron Therapeutics](https://millionrounds.com/company/auron-therapeutics)** Venture · US **Undisclosed** With 5 others
- **Jul** **[Absci](https://millionrounds.com/company/absci)** US **$50M** With 3 others
- **May** **[A2 Biotherapeutics](https://millionrounds.com/company/a2-biotherapeutics)** Grant · US **$300K** With 1 other
- **Apr** **[Deepcell](https://millionrounds.com/company/deepcell)** Venture · US **Undisclosed** With 4 others
- **Jan** **[Leyden Labs](https://millionrounds.com/company/leyden-labs)** NL · Silicon Canals **$70M** With 9 others
- **Jan** **[Umoja Biopharma](https://millionrounds.com/company/umoja-biopharma)** Series C · US **$100M** With 6 others
- **Jan** **[Amplo Biotechnology](https://millionrounds.com/company/amplo-biotechnology)** Grant · US **$2.9M** With 1 other
- **2024** 15 rounds
- **Dec** **[Xcell Biosciences](https://millionrounds.com/company/xcell-biosciences)** Venture · US **$1.4M** With 1 other
- **Dec** **[Meiogenix](https://millionrounds.com/company/meiogenix)** Venture · FR **Undisclosed** With 4 others
- **Sept** **[Arzeda](https://millionrounds.com/company/arzeda)** Growth · US · Firms' own news pages **$38M** With 9 others
- **Sept** **[Genome Medical](https://millionrounds.com/company/genome-medical)** Series D · US **$75M** With 6 others
- **Sept** **[Relay Therapeutics](https://millionrounds.com/company/relay-therapeutics)** US **$200M** With 5 others
- **Aug** **[Molecular Assemblies](https://millionrounds.com/company/molecular-assemblies)** Grant · US **$4.0M** With 3 others
- **Aug** **[Idrx](https://millionrounds.com/company/idrx)** Series B · US **$120M** With 3 others
- **Jul** **[TMRW Life Sciences](https://millionrounds.com/company/tmrw-life-sciences)** Series D · US **$28M** With 3 others
- **Jul** **[Vanqua Bio](https://millionrounds.com/company/vanqua-bio)** Venture · US **$45M** With 3 others
- **Jun** **[Notch Therapeutics](https://millionrounds.com/company/notch-therapeutics)** Venture · CA **$16M** With 2 others
- **May** **[Genomic Life](https://millionrounds.com/company/genomic-life)** Venture · US **$10M** Sole investor
- **Apr** **[Cerevance](https://millionrounds.com/company/cerevance)** Series B · US **$47M** With 3 others
- **Apr** **[Gritstone bio](https://millionrounds.com/company/gritstone-bio)** US **$33M** With 3 others
- **Jan** **[Remix Therapeutics](https://millionrounds.com/company/remix-therapeutics)** Venture · US **$60M** With 4 others
- **Jan** **[Voyager Therapeutics](https://millionrounds.com/company/voyager-therapeutics)** US **$100M** With 3 others
- **2023** 7 rounds
- **Dec** **[Exscientia](https://millionrounds.com/company/exscientia)** Grant · GB **$2.3M** With 4 others
- **Jun** **[Scribe Biosciences](https://millionrounds.com/company/scribe-biosciences)** Venture · US **Undisclosed** With 1 other
- **Apr** **[Orbital Therapeutics](https://millionrounds.com/company/orbital-therapeutics)** Series A · US **$270M** With 4 others
- **Apr** **[Function Oncology](https://millionrounds.com/company/function-oncology)** Series A · US **$28M** With 3 others
- **Mar** **[Flare Therapeutics](https://millionrounds.com/company/flare-therapeutics)** Series B · US **$123M** With 3 others
- **Mar** **[Generation Bio](https://millionrounds.com/company/generation-bio)** US **$76M** With 3 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **5 named**

AF **Alexandria Fisk** Chief Operating Officer i Form ADV

AC **Angelo Crupi** Chief Compliance Officer i Form ADV

ED **Eli D Casdin** Managing Member of the General Partner i Filing they signed

LJ **Lawrence Jude Canzoneri** Chief Financial Officer i Form ADV

SM **Steven Michael Giordano** General Counsel i Form ADV

We also hold **21** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$2.9B** assets it manages Oct 2026

**Registered** investment adviser full reporting to the SEC

- **Legal name:** Casdin Capital, LLC
- **SEC number:** CRD 169579

Funds on its Form ADV

**6** private funds, **$2.6B** in gross assets · filed Mar 2024

Hedge **3** Private equity **2** Venture **1**

- Casdin Partners Master Fund, L.P. *Hedge* 563 investors $1.9B
- Casdin Private Growth Equity Fund II, L.P. *Private equity* 226 investors $402M
- Casdin Private Growth Equity Fund, L.P. *Private equity* 175 investors $243M
- Casdin Venture Opportunities Fund, L.P. *Venture* 46 investors $29M
- Casdin Partners FO1 - MSV, L.P. *Hedge* 2 investors $25M
- Casdin Amplify Fund, L.P. *Hedge* 2 investors $14M

## Exits from the portfolio

Companies it backed that were later bought or listed **2 in all**

**[Foundation Medicine](https://millionrounds.com/company/foundation-medicine)** Bought by Roche **Undisclosed** Jan 2015

**[Foundation Medicine](https://millionrounds.com/company/foundation-medicine)** Listed **$108M** Jul 2013

An exit counts when it came after the firm's first round in the company. From historical deal records.

New fund on file

**$234M**

raised in Nov 2021

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Seed Series A Series B

Median round joined **$65M** the round, not its cheque Alone, median **$8.1M**

Led 1 of 104 rounds **1%**

- **Said size:** $100K – $5.0M
- **Sole investor:** 5 rounds
- **Last cheque:** Oct 2026
- **Exits:** 2 from the portfolio

Rounds by stage said on their site

- Series B said *31*
- Series A said *20*
- Venture *13*
- Series C *6*
- Grant *4*
- Seed said *-*
- Growth said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [Redmile Group](https://millionrounds.com/fund/redmile-group) 13
- [Fidelity](https://millionrounds.com/fund/fidelity) 12
- [Google Ventures](https://millionrounds.com/fund/gv) 12
- [Deerfield](https://millionrounds.com/fund/deerfield) 11
- [Alexandria Venture Investments](https://millionrounds.com/fund/alexandria-venture-investments) 10
- [Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) 10

**Pitching Casdin Capital?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as Casdin Capital. A count of rooms they were both in, not a relationship either has claimed.

[**Redmile Group** VC firm **13** rounds together](https://millionrounds.com/fund/redmile-group)[**Fidelity** VC firm **12** rounds together](https://millionrounds.com/fund/fidelity)[**Google Ventures** Corporate VC **12** rounds together](https://millionrounds.com/fund/gv)[**Deerfield** VC firm **11** rounds together](https://millionrounds.com/fund/deerfield)[**Alexandria Venture Investments** VC firm **10** rounds together](https://millionrounds.com/fund/alexandria-venture-investments)[**Perceptive Advisors** Asset manager **10** rounds together](https://millionrounds.com/fund/perceptive-advisors)[**Invus** Private equity **9** rounds together](https://millionrounds.com/fund/invus)[**Cormorant Asset Management** Private equity **8** rounds together](https://millionrounds.com/fund/cormorant-asset-management)[**Third Rock Ventures** VC firm **8** rounds together](https://millionrounds.com/fund/third-rock-ventures)[**Wellington Management** VC firm **8** rounds together](https://millionrounds.com/fund/wellington-management)[**ARCH Venture Partners** VC firm **7** rounds together](https://millionrounds.com/fund/arch-venture-partners)[**S32** VC firm **7** rounds together](https://millionrounds.com/fund/s32)

## Recently backed

The latest companies Casdin Capital put money into.

[**4D Molecular Therapeutics** $200M · Jun 2026](https://millionrounds.com/company/4d-molecular-therapeutics)[**Revolution Medicines** $1.5B · Apr 2026](https://millionrounds.com/company/revolution-medicines)[**Apella** $80M · Jan 2026](https://millionrounds.com/company/apella)[**Foghorn Therapeutics** $50M · Jan 2026](https://millionrounds.com/company/foghorn-therapeutics)[**Contineum Therapeutics** $99M · Dec 2025](https://millionrounds.com/company/contineum-therapeutics)[**Octave** Oct 2025](https://millionrounds.com/company/octave)

## On podcasts

1 episode naming Casdin Capital in the title.

- [Capital Allocators](https://millionrounds.com/podcasts/capital-allocators) 15 Jul 2021 · 1h 8m Eli Casdin – Casdin Capital (Manager Meetings, EP.02) With [Eli Casdin](https://millionrounds.com/person/eli-casdin) Mentions [Casdin Capital](https://millionrounds.com/fund/casdin-capital)[Google](https://millionrounds.com/fund/google-assistant-investments) Apple PodcastsShow page

## Quick answers about Casdin Capital

### What does Casdin Capital invest in?

Casdin Capital invests most often at Series B and Series A (69% of the rounds on record), in sectors such as Health, Healthier Living and Digital-health.

### How active is Casdin Capital?

104 investments on record, 8 of them in the last 12 months, and it led 1. The most recent was in Oct 2026.

### What has Casdin Capital invested in recently?

Its most recent investments on record: Bolt Biotherapeutics (Undisclosed round, Oct 2026), City Therapeutics (Series B, Jun 2026) and 4D Molecular Therapeutics (Debt, Jun 2026).

### How big are Casdin Capital's cheques?

The median round it joins is $65M. It says it writes cheques of $100K to $5.0M.

### Does Casdin Capital lead rounds?

Sometimes: it led 1 of its 104 investments on record (1%).

### Where does Casdin Capital invest?

Most of the companies it backs are in the United States (90%).

### Is Casdin Capital investing now?

Yes: it is actively investing, with 8 investments in the last 12 months.

### Who does Casdin Capital invest alongside?

Most often Redmile Group (13 rounds together), Fidelity (12 rounds together) and Google Ventures (12 rounds together).

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