# Big Brain Holdings: portfolio, investments and team

> Big Brain Holdings is a vc firm based in United States. 109 investments on record, 4 in the last 12 months, latest Mar 2026.

Source: https://millionrounds.com/fund/big-brain-holdings (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Big Brain Holdings

Last cheque observed Mar 2026; 109 cheques on record.

Email

Deploying now VC firm

Pre-seed Seed Series A Metaverse Nft Crypto

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Deploying now

**11%** of best year **4** **cheques in 12 months**, 109 on record

Since the last cheque **243** days **00** hrs **00** min **00** sec

Median round **$3.2M** Cheque size, as they say **$100K – $5.0M** Rounds led **0 of 109** Sole investor **13 rounds** Mostly in **United States, 45%**

Pitch Big Brain Holdings

## Big Brain Holdings highlights

- 01 4 cheques in the last 12 months
- 02 Mostly Seed and Pre-seed: 80% of its rounds
- 03 Sole investor in 13 rounds, median $2.0M

## What they do

> Big Brain Holdings is a global multi-stage investment firm backing funds and founders accelerating emerging frontiers in technology. From their own website

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** $100K – $5.0M as they say
- **Stages:** Pre-seed Seed Series A Series B
- **Sectors:** Metaverse Nft Crypto
- **Based in:** Weston, United States
- **Cold pitches:** Not accepted

## The record

Every round we can evidence, newest first **109 appearances**

- **2026** 2 rounds
- **Mar** **[Akave](https://millionrounds.com/company/akave)** Seed · US · TechStartups **$6.7M** With 8 others
- **Mar** **[Derivio](https://millionrounds.com/company/derivio)** Seed **$6.0M** With 4 others
- **2025** 23 rounds
- **Dec** **[Zoo Finance](https://millionrounds.com/company/zoo-finance)** Seed · HK **$8.0M** With 1 other
- **Dec** **[Haiku](https://millionrounds.com/company/haiku)** Pre-seed · FR **$1.0M** Sole investor
- **Oct** **[KapKap](https://millionrounds.com/company/kapkap)** Seed · Ventureburn **$10M** With 7 others
- **Oct** **[Grass](https://millionrounds.com/company/grass)** Ventureburn **$10M** With 4 others
- **Oct** **[MegaETH](https://millionrounds.com/company/megaeth)** Token sale · US **$50M** With 2 others
- **Sept** **[Raiku](https://millionrounds.com/company/raiku)** Seed · Ventureburn **$11M** With 5 others
- **Sept** **[Bio Protocol](https://millionrounds.com/company/bio-protocol)** Seed · Ventureburn **$6.9M** With 8 others
- **Sept** **[Sonic](https://millionrounds.com/company/sonic)** Seed · US · TechStartups **$3.5M** With 11 others
- **Sept** **[Yotta Labs](https://millionrounds.com/company/yotta-labs)** Seed · US **$3.5M** With 3 others
- **Aug** **[Levr Bet](https://millionrounds.com/company/levr-bet)** Seed · US **$3.0M** With 3 others
- **Aug** **[Perle AI](https://millionrounds.com/company/perle-ai)** Seed · US **$9.0M** With 4 others
- **Jun** **[Inference Labs](https://millionrounds.com/company/inference-labs)** Seed · CA **$5.3M** With 2 others
- **May** **[Fermi Labs](https://millionrounds.com/company/fermi-labs)** Pre-seed · US **$1.2M** Sole investor
- **Apr** **[Arch Labs](https://millionrounds.com/company/arch-labs)** Series A · US · TechStartups **$13M** With 6 others
- **Apr** **[Optimum](https://millionrounds.com/company/optimum)** Seed · US **$11M** With 4 others
- **Apr** **[CrossCurve Metelayer](https://millionrounds.com/company/crosscurve-metelayer)** Venture · ES **$1.0M** With 2 others
- **Mar** **[M10](https://millionrounds.com/company/m10)** Seed · GB **$3.0M** With 3 others
- **Mar** **[Fortytwo](https://millionrounds.com/company/fortytwo)** Pre-seed · US **$2.3M** With 1 other
- **Mar** **[Arcium](https://millionrounds.com/company/arcium)** Pre-seed · CH **$2.0M** With 5 others
- **Feb** **[Acre](https://millionrounds.com/company/acre)** Venture · GB **$4.0M** With 1 other
- **Feb** **[FrodoBots Lab](https://millionrounds.com/company/frodobots-lab)** Seed · US **$6.0M** With 2 others
- **Jan** **[Ranger Finance](https://millionrounds.com/company/ranger-finance)** Seed · SG **$1.9M** With 1 other
- **Jan** **[Oh](https://millionrounds.com/company/oh)** Seed · GB **$4.5M** Sole investor
- **2024** 34 rounds
- **Dec** **[Sphere](https://millionrounds.com/company/sphere)** Venture · US **$5.0M** With 4 others
- **Nov** **[OASYS NOW](https://millionrounds.com/company/oasys-now)** Seed · NL **$1.0M** With 8 others
- **Oct** **[Flappy Bird](https://millionrounds.com/company/flappy-bird)** Seed · HK **$2.0M** With 1 other
- **Oct** **[Nillion](https://millionrounds.com/company/nillion)** Venture · CH **$25M** With 3 others
- **Sept** **[Open Forest Protocol](https://millionrounds.com/company/open-forest-protocol)** Venture · CH **Undisclosed** With 2 others
- **Sept** **[Initia Labs](https://millionrounds.com/company/initia-labs)** Series A · SG **$14M** With 2 others
- **Sept** **[Octra](https://millionrounds.com/company/octra)** Pre-seed · CH **$4.0M** With 1 other
- **Aug** **[Nepoe](https://millionrounds.com/company/nepoe)** Seed **$9.0M** With 4 others
- **Aug** **[VOID](https://millionrounds.com/company/void)** Series A · US **$11M** With 5 others
- **Aug** **[Soulbound](https://millionrounds.com/company/soulbound)** Seed · US **$4.0M** With 4 others
- **Jul** **[zkLink](https://millionrounds.com/company/zklink)** Venture · SG **Undisclosed** With 6 others
- **Jun** **[Pixelverse](https://millionrounds.com/company/pixelverse)** Seed **$7.5M** With 2 others
- **Jun** **[XOCIETY](https://millionrounds.com/company/xociety)** Seed **$7.5M** With 2 others
- **Jun** **[Decent Land Labs](https://millionrounds.com/company/decent-land-labs)** Seed · GB **$3.0M** With 3 others
- **May** **[Magpie Protocol](https://millionrounds.com/company/magpie-protocol)** Venture **Undisclosed** With 4 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

We hold **5** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What they claim to have backed

From their own portfolio page (on their website)

**45** of 60 we have independently watched raise

[Aethir Data/ AI](https://millionrounds.com/company/aethir)[Agility Robotics Robotics](https://millionrounds.com/company/agility-robotics)[Ahead Computing Advanced](https://millionrounds.com/company/aheadcomputing)[Akave Data/ AI](https://millionrounds.com/company/akave)[Apptronik Robotics Apptronik](https://millionrounds.com/company/apptronik)[Arch Network Crypto](https://millionrounds.com/company/arch)[Arweave Crypto Arweave](https://millionrounds.com/company/arweave)[Bio Protocol Crypto](https://millionrounds.com/company/bio-protocol)[Bulk Crypto Bulk](https://millionrounds.com/company/bulk)[Crossmint](https://millionrounds.com/company/crossmint)[Exo Labs Data/](https://millionrounds.com/company/exo-labs)[Flashbots Crypto Flashbots](https://millionrounds.com/company/flashbots)[FortyTwo AI FortyTwo](https://millionrounds.com/company/fortytwo)[Helius Crypto Helius](https://millionrounds.com/company/helius)[Hyperbolic Data/ AI](https://millionrounds.com/company/hyperbolic)[IKA Crypto IKA](https://millionrounds.com/company/ika)[Inco Crypto Inco](https://millionrounds.com/company/inco)[Inference Labs Data/](https://millionrounds.com/company/inference-labs)[Kash Consumer Kash](https://millionrounds.com/company/kash)[Mach Industries Deeptech](https://millionrounds.com/company/mach-industries)[MegaETH Crypto MegaETH](https://millionrounds.com/company/megaeth)[Monad Crypto Monad](https://millionrounds.com/company/monad)[Mysten Labs Crypto](https://millionrounds.com/company/mysten-labs)[NEAR Protocol Crypto](https://millionrounds.com/company/near)[Nillion Crypto Nillion](https://millionrounds.com/company/nillion)[Octra Crypto Octra](https://millionrounds.com/company/octra)[Panoptic Crypto Panoptic](https://millionrounds.com/company/panoptic)[Panthalassa Data/ AI](https://millionrounds.com/company/panthalassa)[Parallel Life Consumer](https://millionrounds.com/company/parallel)[Poseidon Deeptech Poseidon](https://millionrounds.com/company/poseidon-aerospace)[Pudgy Penguins Consumer](https://millionrounds.com/company/pudgy-penguins)[Pump.fun Consumer Pump.fun](https://millionrounds.com/company/pump)[Raiku Crypto Raiku](https://millionrounds.com/company/raiku)[Reflect Crypto Reflect](https://millionrounds.com/company/reflect)[Reflect Orbital Deeptech](https://millionrounds.com/company/reflect-orbital)[Solana Crypto Solana](https://millionrounds.com/company/solana)[Solayer Crypto Solayer](https://millionrounds.com/company/solayer)[Sphere Crypto Sphere](https://millionrounds.com/company/spherepay)[Stacks Crypto Stacks](https://millionrounds.com/company/stacks)[The Graph Crypto](https://millionrounds.com/company/the-graph)[Utexo Crypto Utexo](https://millionrounds.com/company/utexo)[Vulcan Elements Deeptech](https://millionrounds.com/company/vulcan-elements)[Wormhole Crypto Wormhole](https://millionrounds.com/company/wormhole)[Wynd Data/ AI](https://millionrounds.com/company/wynd)[Yotta Labs Data/](https://millionrounds.com/company/yotta-labs) Ambient AI Ambient Antigma AI Antigma Argument Crypto Argument Avalanche Crypto Avalanche Bitrobot Robotics Bitrobot Collectorcrypt Daxo Robotics Robotics Dyna Robotics Robotics Enhanced Games Consumer Exabits Data/ AI FrodoBots Data/ AI GTE Consumer GTE Grass Data/ AI Hemi Crypto Hemi Initia Crypto Initia and 17 more

Weaker than a round we watched, stronger than a list somebody sold us. A firm is far less willing to put a company on its own site that it never funded.

## The cheque

Pre-seed Seed Series A

Median round joined **$3.2M** the round, not its cheque Alone, median **$2.0M**

Led 0 of 109 rounds **0%**

- **Said size:** $100K – $5.0M
- **Sole investor:** 13 rounds
- **Last cheque:** Mar 2026

Rounds by stage said on their site

- Seed said *70*
- Pre-seed said *16*
- Venture *13*
- Series A said *8*
- Token sale *1*
- Series B said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [Animoca Brands](https://millionrounds.com/fund/animoca-brands) 8
- [NGC Ventures](https://millionrounds.com/fund/ngc-ventures) 8
- [Borderless Capital](https://millionrounds.com/fund/borderless-capital) 7
- [Cogitent Ventures](https://millionrounds.com/fund/cogitent-ventures) 7
- [GSR](https://millionrounds.com/fund/gsr) 7
- [Foresight Ventures](https://millionrounds.com/fund/foresight-ventures) 5

**Pitching Big Brain Holdings?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as Big Brain Holdings. A count of rooms they were both in, not a relationship either has claimed.

[**Animoca Brands** Accelerator **8** rounds together](https://millionrounds.com/fund/animoca-brands)[**NGC Ventures** VC firm **8** rounds together](https://millionrounds.com/fund/ngc-ventures)[**Borderless Capital** Accelerator **7** rounds together](https://millionrounds.com/fund/borderless-capital)[**Cogitent Ventures** VC firm **7** rounds together](https://millionrounds.com/fund/cogitent-ventures)[**GSR** VC firm **7** rounds together](https://millionrounds.com/fund/gsr)[**Foresight Ventures** Accelerator **5** rounds together](https://millionrounds.com/fund/foresight-ventures)[**OKX Ventures** Corporate VC **5** rounds together](https://millionrounds.com/fund/okx-ventures)[**YZi Labs** VC firm **5** rounds together](https://millionrounds.com/fund/yzi-labs)[**Coinbase Ventures** Corporate VC **4** rounds together](https://millionrounds.com/fund/coinbase)[**Galaxy Interactive** VC firm **4** rounds together](https://millionrounds.com/fund/galaxy-interactive-2)[**Hashed** VC firm **4** rounds together](https://millionrounds.com/fund/hashed)[**Jump Crypto** Corporate VC **4** rounds together](https://millionrounds.com/fund/jump-crypto)

## Recently backed

The latest companies Big Brain Holdings put money into.

[**Akave** $6.7M · Mar 2026](https://millionrounds.com/company/akave)[**Derivio** $6.0M · Mar 2026](https://millionrounds.com/company/derivio)[**Zoo Finance** $8.0M · Dec 2025](https://millionrounds.com/company/zoo-finance)[**Grass** $10M · Oct 2025](https://millionrounds.com/company/grass)[**Raiku** $11M · Sept 2025](https://millionrounds.com/company/raiku)[**Bio Protocol** $6.9M · Sept 2025](https://millionrounds.com/company/bio-protocol)

## Quick answers about Big Brain Holdings

### What does Big Brain Holdings invest in?

Big Brain Holdings invests most often at Seed and Pre-seed (80% of the rounds on record), in sectors such as Metaverse, Nft and Crypto.

### How active is Big Brain Holdings?

109 investments on record, 4 of them in the last 12 months. The most recent was in Mar 2026.

### What has Big Brain Holdings invested in recently?

Its most recent investments on record: Akave (Seed, Mar 2026), Derivio (Seed, Mar 2026) and Zoo Finance (Seed, Dec 2025).

### How big are Big Brain Holdings's cheques?

The median round it joins is $3.2M. It says it writes cheques of $100K to $5.0M.

### Does Big Brain Holdings lead rounds?

Rarely, if at all: none of its 109 investments on record names it as the lead.

### Where does Big Brain Holdings invest?

Most of the companies it backs are in the United States (45%), the United Kingdom (13%) and Switzerland (13%).

### Is Big Brain Holdings investing now?

Yes: it is actively investing, with 4 investments in the last 12 months.

### Who does Big Brain Holdings invest alongside?

Most often Animoca Brands (8 rounds together), NGC Ventures (8 rounds together) and Borderless Capital (7 rounds together).

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