# Astellas Venture Management: portfolio, investments and team

> Astellas Venture Management is a corporate vc based in United States. 29 investments on record, 1 in the last 12 months, latest Apr 2026.

Source: https://millionrounds.com/fund/astellas-venture-management (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# Astellas Venture Management

Last cheque observed Apr 2026; 29 cheques on record.

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Deploying now Corporate VC

Pre-seed Seed Series A Therapeutics Platform Technologies

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Deploying now

**100%** of best year **1** **cheques in 12 months**, 29 on record

Since the last cheque **206** days **00** hrs **00** min **00** sec

Median round **$24M** Rounds led **0 of 29** Sole investor **1 rounds** Exits **3 from the portfolio** Mostly in **United States, 62%**

Pitch Astellas Venture Management

## Astellas Venture Management highlights

- 01 1 cheques in the last 12 months
- 02 Mostly Series B and Series A: 69% of its rounds
- 03 Sole investor in 1 rounds, median undisclosed
- 04 3 exits from the portfolio

## What they do

> AVM is the wholly-owned venture capital organization within Astellas, dedicated to supporting pre-clinical, cutting-edge science that can bring VALUE to patients. From their own website

- **Type:** Corporate VC
- **Cheque size:** Not stated
- **Stages:** Pre-seed Seed Series A
- **Sectors:** Therapeutics Platform Technologies
- **Based in:** London, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **29 appearances**

- **2026** 1 round
- **Apr** **[Sidewinder Therapeutics](https://millionrounds.com/company/sidewinder-therapeutics)** Series B · US · Ventureburn **$137M** With 8 others
- **2021** 1 round
- **Mar** **[NeoPhore Limited](https://millionrounds.com/company/neophore-limited)** Series B · GB · Firms' own news pages **$21M** With 4 others
- **2019** 2 rounds
- **Nov** **[Heartseed](https://millionrounds.com/company/heartseed)** Series B · JP · FinSMEs **$26M** With 4 others
- **Aug** **[Cleave Therapeutics](https://millionrounds.com/company/cleave-therapeutics)** Series C · US · Businesswire **$12M** With 8 others
- **2014** 5 rounds
- **Dec** **[Crescendo Biologics](https://millionrounds.com/company/crescendo-biologics)** Venture · GB **Undisclosed** Sole investor
- **Oct** **[Viamet Pharmaceuticals](https://millionrounds.com/company/viamet-pharmaceuticals)** Series D · US **$60M** With 4 others
- **Oct** **[Raze Therapeutics](https://millionrounds.com/company/raze-therapeutics)** Series A · US **$24M** With 6 others
- **Oct** **[Bicycle Therapeutics](https://millionrounds.com/company/bicycle-therapeutics)** Series A · GB **$32M** With 4 others
- **Apr** **[Crescendo Biologics](https://millionrounds.com/company/crescendo-biologics)** Series A · GB **$3.0M** With 3 others
- **2013** 4 rounds
- **Dec** **[Crescendo Biologics](https://millionrounds.com/company/crescendo-biologics)** Series A · GB **$27M** With 2 others
- **May** **[Effector Therapeutics](https://millionrounds.com/company/effector-therapeutics)** Series A · US · fiercebiotech.com **$45M** With 6 others
- **Feb** **[DecImmune Therapeutics](https://millionrounds.com/company/decimmune-therapeutics)** Growth · US · finsmes.com **$2.3M** With 2 others
- **Jan** **[Cleave Biosciences](https://millionrounds.com/company/cleave-biosciences)** Growth · US **$15M** With 5 others
- **2012** 3 rounds
- **Dec** **[Bicycle Therapeutics](https://millionrounds.com/company/bicycle-therapeutics)** GB · finsmes.com **$6.0M** With 4 others
- **Sept** **[F2G](https://millionrounds.com/company/f2g)** Venture · GB · fiercebiotech.com **$30M** With 6 others
- **Jun** **[PhaseBio Pharmaceuticals](https://millionrounds.com/company/phasebio-pharmaceuticals)** Series B · US · pevc.dowjones.com **$23M** With 4 others
- **2011** 3 rounds
- **Oct** **[Cleave Biosciences](https://millionrounds.com/company/cleave-biosciences)** Series A · US · finsmes.com **$44M** With 5 others
- **Jul** **[Verastem](https://millionrounds.com/company/verastem)** Series B · US · masshightech.com **$32M** With 5 others
- **May** **[Fate Therapeutics](https://millionrounds.com/company/fate-therapeutics)** Series B · US · sec.gov **$36M** With 5 others
- **2010** 2 rounds
- **Sept** **[DecImmune Therapeutics](https://millionrounds.com/company/decimmune-therapeutics)** Venture · US · finsmes.com **$3.2M** With 2 others
- **Jun** **[Nereus Pharmaceuticals](https://millionrounds.com/company/nereus-pharmaceuticals)** Series E · US · onbiovc.com **$20M** With 6 others
- **2009** 3 rounds
- **Oct** **[Epizyme](https://millionrounds.com/company/epizyme)** Series B · US · fiercebiotech.com **$32M** With 4 others
- **Jul** **[Viamet Pharmaceuticals](https://millionrounds.com/company/viamet-pharmaceuticals)** Series B · US · sec.gov **$25M** With 6 others
- **Jan** **[Intradigm Corporation](https://millionrounds.com/company/intradigm-corporation)** Series B · US · fiercebiotech.com **$21M** With 7 others
- **2008** 2 rounds
- **Aug** **[F2G](https://millionrounds.com/company/f2g)** Venture · GB · f2g.com **$12M** With 3 others
- **Jun** **[Inimex Pharmaceuticals](https://millionrounds.com/company/inimex-pharmaceuticals)** Series B · CA **$22M** With 7 others
- **2007** 1 round
- **Aug** **[Nereus Pharmaceuticals](https://millionrounds.com/company/nereus-pharmaceuticals)** Series D · US **$45M** With 12 others
- **2006** 2 rounds
- **Sept** **[CoMentis](https://millionrounds.com/company/comentis)** Series B · US **$50M** With 4 others
- **Feb** **[Lectus Therapeutics](https://millionrounds.com/company/lectus-therapeutics)** Series A · GB · lectustherapeutics.com **$14M** With 3 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

We hold **5** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## Exits from the portfolio

Companies it backed that were later bought or listed **3 in all**

**[Verastem](https://millionrounds.com/company/verastem)** Listed **$52M** Jul 2013

**[Epizyme](https://millionrounds.com/company/epizyme)** Listed **$60M** May 2013

**[Intradigm Corporation](https://millionrounds.com/company/intradigm-corporation)** Bought by [Silence Therapeutics](https://millionrounds.com/fund/silence-therapeutics) **Undisclosed** Dec 2009

An exit counts when it came after the firm's first round in the company. From historical deal records.

## The cheque

Pre-seed Seed Series A

Median round joined **$24M** the round, not its cheque Alone, median **-**

Led 0 of 29 rounds **0%**

- **Sole investor:** 1 rounds
- **Last cheque:** Apr 2026
- **Exits:** 3 from the portfolio

Rounds by stage said on their site

- Series B *11*
- Series A said *7*
- Venture *4*
- Growth *2*
- Series D *2*
- Pre-seed said *-*
- Seed said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [Novartis Venture Fund](https://millionrounds.com/fund/novartis-venture-fund) 8
- [OrbiMed](https://millionrounds.com/fund/orbimed) 4
- [Roche Venture Fund](https://millionrounds.com/fund/roche-venture-fund) 4
- [U.S. Venture Partners](https://millionrounds.com/fund/u-s-venture-partners-usvp) 4
- [5AM Ventures](https://millionrounds.com/fund/5am-ventures) 3
- [Alta Partners](https://millionrounds.com/fund/alta-partners) 3

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## Who they invest alongside

The investors most often in the same rounds as Astellas Venture Management. A count of rooms they were both in, not a relationship either has claimed.

[**Novartis Venture Fund** Corporate VC **8** rounds together](https://millionrounds.com/fund/novartis-venture-fund)[**OrbiMed** Private equity **4** rounds together](https://millionrounds.com/fund/orbimed)[**Roche Venture Fund** Corporate VC **4** rounds together](https://millionrounds.com/fund/roche-venture-fund)[**U.S. Venture Partners** VC firm **4** rounds together](https://millionrounds.com/fund/u-s-venture-partners-usvp)[**5AM Ventures** VC firm **3** rounds together](https://millionrounds.com/fund/5am-ventures)[**Alta Partners** VC firm **3** rounds together](https://millionrounds.com/fund/alta-partners)[**Atlas Venture** VC firm **3** rounds together](https://millionrounds.com/fund/atlas-venture)[**Clarus Ventures** VC firm **3** rounds together](https://millionrounds.com/fund/blackstone)[**Hatteras Venture Partners** VC firm **3** rounds together](https://millionrounds.com/fund/hatteras-venture-partners)[**MPM Capital** Private equity **3** rounds together](https://millionrounds.com/fund/mpm-bioimpact)[**New Enterprise Associates** VC firm **3** rounds together](https://millionrounds.com/fund/new-enterprise-associates)[**Osage University Partners** VC firm **3** rounds together](https://millionrounds.com/fund/osage-university-partners)

## Recently backed

The latest companies Astellas Venture Management put money into.

[**Sidewinder Therapeutics** $137M · Apr 2026](https://millionrounds.com/company/sidewinder-therapeutics)[**Heartseed** $26M · Nov 2019](https://millionrounds.com/company/heartseed)[**Cleave Therapeutics** $12M · Aug 2019](https://millionrounds.com/company/cleave-therapeutics)

## Quick answers about Astellas Venture Management

### What does Astellas Venture Management invest in?

Astellas Venture Management invests most often at Series B and Series A (69% of the rounds on record), in sectors such as Therapeutics and Platform Technologies.

### How active is Astellas Venture Management?

29 investments on record, 1 of them in the last 12 months. The most recent was in Apr 2026.

### What has Astellas Venture Management invested in recently?

Its most recent investments on record: Sidewinder Therapeutics (Series B, Apr 2026), NeoPhore Limited (Series B, Mar 2021) and Heartseed (Series B, Nov 2019).

### How big are Astellas Venture Management's cheques?

The median round it joins is $24M.

### Does Astellas Venture Management lead rounds?

Rarely, if at all: none of its 29 investments on record names it as the lead.

### Where does Astellas Venture Management invest?

Most of the companies it backs are in the United States (62%) and the United Kingdom (31%).

### Is Astellas Venture Management investing now?

Yes: it is actively investing, with 1 investments in the last 12 months.

### Who does Astellas Venture Management invest alongside?

Most often Novartis Venture Fund (8 rounds together), OrbiMed (4 rounds together) and Roche Venture Fund (4 rounds together).

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