# 5AM Ventures: portfolio, investments and team

> 5AM Ventures is a vc firm based in United States. 147 investments on record, 9 in the last 12 months, latest Oct 2026. Portfolio, stages, co-investors and team.

Source: https://millionrounds.com/fund/5am-ventures (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# 5AM Ventures

Last cheque observed Oct 2026; 147 cheques on record.

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Deploying now New fund $285M, Mar 2021 VC firm

Seed Series A Series B Biopharmaceuticals Biotechnology Drug_delivery

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Deploying now

**69%** of best year **9** **cheques in 12 months**, 147 on record

Since the last cheque **12** days **00** hrs **00** min **00** sec

Median round **$55M** Cheque size, as they say **$100K – $5.0M** Rounds led **0 of 147** Sole investor **13 rounds** Exits **10 from the portfolio** Mostly in **United States, 92%**

Pitch 5AM Ventures

## 5AM Ventures highlights

- 01 9 cheques in the last 12 months
- 02 Mostly Series A and Series B: 62% of its rounds
- 03 Sole investor in 13 rounds, median $13M
- 04 10 exits from the portfolio

## What they do

> We’re a life science venture capital firm founded in 2002. From their own website

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** $100K – $5.0M as they say
- **Stages:** Seed Series A Series B Growth Pre-IPO
- **Sectors:** Biopharmaceuticals Biotechnology Drug_delivery
- **Based in:** San Francisco, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **147 appearances**

- **2026** 7 rounds
- **Oct** **[Nouscom](https://millionrounds.com/company/nouscom)** Series D · CH · Revelation Partners **$135M** With 14 others
- **Jun** **[IDEAYA Biosciences](https://millionrounds.com/company/ideaya-biosciences)** US **$345M** With 3 others
- **Jun** **[Enliven Therapeutics](https://millionrounds.com/company/enliven-therapeutics)** US **$460M** With 3 others
- **Jan** **[Mendra](https://millionrounds.com/company/mendra)** Series A · US **$82M** With 4 others
- **Jan** **[Precede Biosciences](https://millionrounds.com/company/precede-biosciences)** Series B · US **$64M** With 2 others
- **Jan** **[Kinaset Therapeutics](https://millionrounds.com/company/kinaset-therapeutics)** Series B · US **$103M** With 3 others
- **Jan** **[Spruce Biosciences](https://millionrounds.com/company/spruce-biosciences)** Venture · US **Undisclosed** With 3 others
- **2025** 9 rounds
- **Dec** **[ProLynx](https://millionrounds.com/company/prolynx)** Series A · US **$70M** With 3 others
- **Nov** **[Lifordi Immunotherapeutics](https://millionrounds.com/company/lifordi-immunotherapeutics)** Venture · US **$42M** With 3 others
- **Jul** **[MapLight Therapeutics](https://millionrounds.com/company/maplight-therapeutics)** Series D · US · Avego Management **$373M** With 8 others
- **Jul** **[Fellow Health](https://millionrounds.com/company/fellow-health)** Series B · US **$24M** With 2 others
- **Jul** **[Renasant Bio](https://millionrounds.com/company/renasant-bio)** Seed · US **$55M** With 3 others
- **May** **[GlycoEra](https://millionrounds.com/company/glycoera)** Series B · CH · TechStartups **$130M** With 8 others
- **Mar** **[Latigo Biotherapeutics](https://millionrounds.com/company/latigo-biotherapeutics)** Series B · US **$150M** With 4 others
- **Mar** **[Surrozen](https://millionrounds.com/company/surrozen)** US **$175M** With 3 others
- **Feb** **[Tectonic Therapeutic](https://millionrounds.com/company/tectonic-therapeutic)** US **$185M** With 2 others
- **2024** 12 rounds
- **Sept** **[Deverra Therapeutics](https://millionrounds.com/company/deverra-therapeutics)** Crowdfunding · US **$972K** Sole investor
- **Aug** **[scPharmaceuticals](https://millionrounds.com/company/scpharmaceuticals)** Debt · US **$125M** With 3 others
- **Jul** **[Magnetic Insight](https://millionrounds.com/company/magnetic-insight)** Venture · US **Undisclosed** With 4 others
- **Jul** **[IDEAYA Biosciences](https://millionrounds.com/company/ideaya-biosciences)** US **$263M** With 3 others
- **Jul** **[TMRW Life Sciences](https://millionrounds.com/company/tmrw-life-sciences)** Series D · US **$28M** With 3 others
- **Jun** **[RareCyte](https://millionrounds.com/company/rarecyte)** Venture · US **$20M** Sole investor
- **Jun** **[Entrada Therapeutics](https://millionrounds.com/company/entrada-therapeutics)** US **$100M** With 6 others
- **May** **[Karius](https://millionrounds.com/company/karius)** Series C · US **$100M** With 6 others
- **May** **[Bioz](https://millionrounds.com/company/bioz)** Venture · US **Undisclosed** With 2 others
- **Apr** **[Rallybio](https://millionrounds.com/company/rallybio)** US **$6.6M** With 2 others
- **Mar** **[Nouscom](https://millionrounds.com/company/nouscom)** Series C · CH **$7.6M** With 4 others
- **Jan** **[Skye Bioscience](https://millionrounds.com/company/skye-bioscience)** US **$50M** Sole investor
- **2023** 5 rounds
- **Nov** **[Halio](https://millionrounds.com/company/halio)** Venture · US **$70M** With 3 others
- **Sept** **[Nvelop Therapeutics](https://millionrounds.com/company/nvelop-therapeutics)** Seed · US **$100M** With 1 other
- **Aug** **[Radionetics Oncology](https://millionrounds.com/company/radionetics-oncology)** Series A · US **$53M** With 1 other
- **May** **[Nido Biosciences](https://millionrounds.com/company/nido-biosciences)** Series B · US **$87M** With 2 others
- **Jan** **[Expansion Therapeutics](https://millionrounds.com/company/expansion-therapeutics)** Venture · US **$6.9M** With 4 others
- **2022** 4 rounds
- **Nov** **[Escient Pharmaceuticals](https://millionrounds.com/company/escient-pharmaceuticals)** Series C · US **$120M** With 4 others
- **Sept** **[Novome Biotechnologies](https://millionrounds.com/company/novome-biotechnologies)** Series B · US **$44M** With 4 others
- **Aug** **[CinCor Pharma](https://millionrounds.com/company/cincor-pharma)** US **$225M** With 7 others
- **Apr** **[Portal Instruments](https://millionrounds.com/company/portal-instruments)** Venture · US **$7.0M** With 1 other
- **2021** 4 rounds
- **Dec** **[Pear Therapeutics](https://millionrounds.com/company/pear-therapeutics)** US **$125M** With 5 others
- **Aug** **[Neurogastrx](https://millionrounds.com/company/neurogastrx)** Series B · US **$60M** With 4 others
- **May** **[Soteria Biotherapeutics](https://millionrounds.com/company/soteria-biotherapeutics)** Series A **$42M** With 2 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **6 named**

AJ **Andrew James Schwab** Member, 5Am Venture Management LLC i Form ADV

JD **John David Diekman** Executive Officer i Filing they signed

KM **Kush M. Parmar** Member, 5Am Venture Management, LLC i Form ADV

LA **Lauren Alison Daniel** Chief Compliance Officer i Form ADV

PA **Paul A Stone** Partner, Chief Legal Officer i Form ADV

SM **Scott Michael Rocklage** Executive Officer i Filing they signed

We also hold **39** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$1.1B** assets it manages Oct 2026

**5+** funds on file numbered funds in its name

**Registered** investment adviser full reporting to the SEC

- **Legal name:** 5am Venture Management, LLC
- **SEC number:** CRD 160395

Funds on its Form ADV

**11** private funds, **$1.5B** in gross assets · filed Nov 2024

Venture **9** Private equity **2**

- 5AM Ventures VII, L.P. *Venture* 106 investors $413M
- 5AM Ventures VI, L.P. *Venture* 87 investors $376M
- 5AM Opportunities II, L.P. *Private equity* 86 investors $320M
- 5AM Ventures V, L.P. *Venture* 81 investors $150M
- 5AM Ventures IV, L.P. *Venture* 50 investors $82M
- 5AM Opportunities I, L.P. *Private equity* 49 investors $68M
- 5AM Ventures II, L.P. *Venture* 45 investors $27M
- 5AM Ventures III, L.P. *Venture* 45 investors $14M
- 5AM Co-Investors IV, L.P. *Venture* 33 investors $3.4M
- 5AM Co-Investors II, L.P. *Venture* 31 investors $1.1M

And 1 more on the filing.

## Exits from the portfolio

Companies it backed that were later bought or listed **10 in all**

**[Novira Therapeutics](https://millionrounds.com/company/novira-therapeutics)** Bought by [Johnson & Johnson](https://millionrounds.com/fund/johnson-and-johnson) **Undisclosed** Nov 2015

**[Calibrium](https://millionrounds.com/company/calibrium)** Bought by [Novo Nordisk](https://millionrounds.com/fund/novo-nordisk) **Undisclosed** Aug 2015

**[Ikaria](https://millionrounds.com/company/ikaria)** Bought by [Mallinckrodt](https://millionrounds.com/fund/mallinckrodt) **$2.3B** Mar 2015

**[DVS Sciences](https://millionrounds.com/company/dvs-sciences)** Bought by Fluidigm **$208M** Jan 2014

**[Pearl Therapeutics](https://millionrounds.com/company/pearl-therapeutics)** Bought by [AstraZeneca](https://millionrounds.com/fund/astrazeneca) **$1.1B** Jun 2013

**[KaloBios Pharmaceuticals](https://millionrounds.com/company/kalobios-pharmaceuticals)** Listed **Undisclosed** Jan 2013

**[Incline Therapeutics](https://millionrounds.com/company/incline-therapeutics)** Bought by The Medicines Company **Undisclosed** Dec 2012

**[Semprus BioSciences](https://millionrounds.com/company/semprus-biosciences)** Bought by Teleflex **$30M** Jun 2012

**[Synosia Therapeutics](https://millionrounds.com/company/synosia-therapeutics)** Bought by Biotie Therapies **$122M** Jan 2011

**[Marcadia Biotech](https://millionrounds.com/company/marcadia-biotech)** Bought by Roche **Undisclosed** Dec 2010

An exit counts when it came after the firm's first round in the company. From historical deal records.

New fund on file

**$285M**

raised in Mar 2021

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Seed Series A Series B

Median round joined **$55M** the round, not its cheque Alone, median **$13M**

Led 0 of 147 rounds **0%**

- **Said size:** $100K – $5.0M
- **Sole investor:** 13 rounds
- **Last cheque:** Oct 2026
- **Exits:** 10 from the portfolio

Rounds by stage said on their site

- Series A said *41*
- Series B said *33*
- Venture *20*
- Series C *17*
- Series D *9*
- Seed said *-*
- Growth said *-*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [Versant Ventures](https://millionrounds.com/fund/versant-ventures) 26
- [OrbiMed](https://millionrounds.com/fund/orbimed) 22
- [ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) 12
- [Canaan](https://millionrounds.com/fund/canaan-partners) 12
- [New Leaf Venture Partners](https://millionrounds.com/fund/new-leaf-venture-partners) 12
- [Clarus Ventures](https://millionrounds.com/fund/blackstone) 9

**Pitching 5AM Ventures?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as 5AM Ventures. A count of rooms they were both in, not a relationship either has claimed.

[**Versant Ventures** VC firm **26** rounds together](https://millionrounds.com/fund/versant-ventures)[**OrbiMed** Private equity **22** rounds together](https://millionrounds.com/fund/orbimed)[**ARCH Venture Partners** VC firm **12** rounds together](https://millionrounds.com/fund/arch-venture-partners)[**Canaan** VC firm **12** rounds together](https://millionrounds.com/fund/canaan-partners)[**New Leaf Venture Partners** VC firm **12** rounds together](https://millionrounds.com/fund/new-leaf-venture-partners)[**Clarus Ventures** VC firm **9** rounds together](https://millionrounds.com/fund/blackstone)[**Perceptive Advisors** Asset manager **8** rounds together](https://millionrounds.com/fund/perceptive-advisors)[**Frazier Healthcare Partners** Private equity **7** rounds together](https://millionrounds.com/fund/frazier-healthcare-partners)[**Novo Holdings** VC firm **7** rounds together](https://millionrounds.com/fund/novo-ventures)[**RA Capital Management** Private equity **7** rounds together](https://millionrounds.com/fund/ra-capital-management)[**Sofinnova Investments** VC firm **7** rounds together](https://millionrounds.com/fund/sofinnova-investments)[**Aravis Ventures** Private equity **6** rounds together](https://millionrounds.com/fund/aravis-sa)

## Recently backed

The latest companies 5AM Ventures put money into.

[**Nouscom** $135M · Oct 2026](https://millionrounds.com/company/nouscom)[**IDEAYA Biosciences** $345M · Jun 2026](https://millionrounds.com/company/ideaya-biosciences)[**Enliven Therapeutics** $460M · Jun 2026](https://millionrounds.com/company/enliven-therapeutics)[**Mendra** $82M · Jan 2026](https://millionrounds.com/company/mendra)[**Precede Biosciences** $64M · Jan 2026](https://millionrounds.com/company/precede-biosciences)[**Kinaset Therapeutics** $103M · Jan 2026](https://millionrounds.com/company/kinaset-therapeutics)

## Quick answers about 5AM Ventures

### What does 5AM Ventures invest in?

5AM Ventures invests most often at Series A and Series B (62% of the rounds on record), in sectors such as Biopharmaceuticals, Biotechnology and Drug_delivery.

### How active is 5AM Ventures?

147 investments on record, 9 of them in the last 12 months. The most recent was in Oct 2026.

### What has 5AM Ventures invested in recently?

Its most recent investments on record: Nouscom (Series D, Oct 2026), IDEAYA Biosciences (Undisclosed round, Jun 2026) and Enliven Therapeutics (Undisclosed round, Jun 2026).

### How big are 5AM Ventures's cheques?

The median round it joins is $55M. It says it writes cheques of $100K to $5.0M.

### Does 5AM Ventures lead rounds?

Rarely, if at all: none of its 147 investments on record names it as the lead.

### Where does 5AM Ventures invest?

Most of the companies it backs are in the United States (92%) and Switzerland (8%).

### Is 5AM Ventures investing now?

Yes: it is actively investing, with 9 investments in the last 12 months.

### Who does 5AM Ventures invest alongside?

Most often Versant Ventures (26 rounds together), OrbiMed (22 rounds together) and ARCH Venture Partners (12 rounds together).

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