# 2048 Ventures: portfolio, investments and team

> 2048 Ventures is a vc firm based in United States. 61 investments on record, 9 in the last 12 months, latest Sept 2026.

Source: https://millionrounds.com/fund/2048-ventures (Millionrounds; every figure on the page links to its filing or article)

United States · [Investor](https://millionrounds.com/investors)

# 2048 Ventures

Last cheque observed Sep 2026; 61 cheques on record.

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Deploying now New fund $82M, Mar 2026 VC firm

Pre-seed Pharmaceuticals Artificial Intelligence Therapeutics

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Deploying now

**60%** of best year **9** **cheques in 12 months**, 61 on record

Since the last cheque **60** days **00** hrs **00** min **00** sec

Median round **$3.8M** Cheque size, as they say **$300K – $2.0M** Rounds led **1 of 61** Sole investor **9 rounds** Mostly in **United States, 80%**

Pitch 2048 Ventures

## 2048 Ventures highlights

- 01 9 cheques in the last 12 months
- 02 Mostly Seed and Pre-seed: 60% of its rounds
- 03 Sole investor in 9 rounds, median $1.1M

## What they do

- **Type:** VC firm (from a list, unverified)
- **Cheque size:** $300K – $2.0M as they say
- **Stages:** Pre-seed
- **Sectors:** Pharmaceuticals Artificial Intelligence Therapeutics
- **Based in:** New York, United States
- **Cold pitches:** Not stated

## The record

Every round we can evidence, newest first **61 appearances**

- **2026** 9 rounds
- **Sept** **[TwoStep Therapeutics](https://millionrounds.com/company/twostep-therapeutics)** Series A · US **$63M** With 2 others
- **Jul** **[Genius AI](https://millionrounds.com/company/genius-ai)** Growth · US · Ventureburn **$44M** With 7 others
- **Jul** **[Nebex](https://millionrounds.com/company/nebex)** Seed · US · TechStartups **$30M** With 12 others
- **May** **[Wirestock](https://millionrounds.com/company/wirestock)** Series A · US · TechCrunch **$23M** With 6 others
- **May** **[Century Health](https://millionrounds.com/company/century-health)** Seed · US **$5.0M** With 4 others
- **May** **[Fazeshift](https://millionrounds.com/company/fazeshift)** Series A · US **$4.0M** With 4 others
- **May** **[Rely](https://millionrounds.com/company/rely)** Seed · US **$4.5M** With 1 other
- **Mar** **[Pocket](https://millionrounds.com/company/pocket)** Pre-seed · US **$1.4M** Sole investor
- **Jan** **[TwoStep Therapeutics](https://millionrounds.com/company/twostep-therapeutics)** Series A · US **$21M** With 2 others
- **2025** 14 rounds
- **Oct** **[Caravel Bio](https://millionrounds.com/company/caravel-bio)** Grant · US **$7.8M** With 3 others
- **Oct** **[Enurgen](https://millionrounds.com/company/enurgen)** Seed · CA **$4.1M** With 2 others
- **Sept** **[Nionyx Bio](https://millionrounds.com/company/nionyx-bio)** Seed · US **$4.0M** With 1 other
- **Sept** **[Wareclouds](https://millionrounds.com/company/wareclouds)** Venture · CL **Undisclosed** Sole investor
- **Aug** **[Pageport](https://millionrounds.com/company/pageport)** Seed · US **$3.3M** With 2 others
- **Aug** **[Inso Biosciences](https://millionrounds.com/company/inso-biosciences)** Venture · US **Undisclosed** With 3 others
- **Jul** **[Romix Biosciences](https://millionrounds.com/company/romix-biosciences)** Pre-seed · US **$600K** Sole investor
- **Jun** **[Kascaid](https://millionrounds.com/company/kascaid)** Pre-seed · US **$2.3M** With 3 others
- **May** **[Nimbus Health](https://millionrounds.com/company/nimbus-health)** Seed · US **$12M** With 1 other
- **Apr** **[Rondah AI](https://millionrounds.com/company/rondah-ai)** Pre-seed · US **$1.8M** With 1 other
- **Apr** **[Adaptis](https://millionrounds.com/company/adaptis)** Seed · CA **$4.0M** With 3 others
- **Apr** **[Groundfloor](https://millionrounds.com/company/groundfloor)** Venture · US **Undisclosed** With 3 others
- **Apr** **[Rondah AI](https://millionrounds.com/company/rondah-ai)** Pre-seed · US **$3.5M** With 1 other
- **Feb** **[Humane Genomics](https://millionrounds.com/company/humane-genomics)** Seed · US **$4.0M** With 3 others
- **2024** 12 rounds
- **Nov** **[Impilo](https://millionrounds.com/company/impilo)** Series A · US **$12M** With 2 others
- **Oct** **[Psyrin](https://millionrounds.com/company/psyrin)** Pre-seed · US **$1.0M** With 3 others
- **Sept** **[Frate](https://millionrounds.com/company/frate)** Seed · CA **$2.6M** With 2 others
- **May** **[FemTherapeutics, Inc.](https://millionrounds.com/company/femtherapeutics-inc)** Venture · CA **Undisclosed** With 3 others
- **May** **[Aerodome](https://millionrounds.com/company/aerodome)** Series A · US **$22M** With 4 others
- **Apr** **[Tetsuwan Scientific](https://millionrounds.com/company/tetsuwan-scientific)** Pre-seed · US **$2.7M** With 1 other
- **Apr** **[Centro Commerce](https://millionrounds.com/company/centro-commerce)** Venture · CA **Undisclosed** With 3 others
- **Apr** **[Impacked](https://millionrounds.com/company/impacked)** Seed · US **$4.7M** With 4 others
- **Mar** **[Century Health](https://millionrounds.com/company/century-health)** Pre-seed · US **$2.0M** With 2 others
- **Feb** **[Ripple AI](https://millionrounds.com/company/ripple-ai)** Pre-seed · US **$1.2M** Sole investor
- **Feb** **[Neobe Therapeutics](https://millionrounds.com/company/neobe-therapeutics)** Seed · GB **$2.3M** With 1 other
- **Jan** **[Acorn Finance](https://millionrounds.com/company/acorn-finance)** Series A · US **$5.0M** With 4 others
- **2023** 7 rounds
- **Dec** **[Atlas](https://millionrounds.com/company/atlas)** Seed · US **$2.7M** Sole investor
- **Nov** **[mealco](https://millionrounds.com/company/mealco)** Venture · US **Undisclosed** With 2 others
- **Aug** **[Supademo](https://millionrounds.com/company/supademo)** Pre-seed · US **$1.0M** Sole investor
- **Jun** **[Aclid](https://millionrounds.com/company/aclid)** Seed · US **$3.3M** Sole investor
- **Jun** **[Passage](https://millionrounds.com/company/passage)** Seed · CA **$30M** With 2 others

An announcement gives the size of the round, not the size of this investor's cheque: the only rounds that imply a cheque are those where they were the sole named investor.

## The team

Named by the firm itself, on a filing, its Form ADV or its company registration **3 named**

AI **Alex Iskold** Managing Director i Filing they signed

AV **Alexander V Iskold** Manager and Member i Form ADV

PS **Paul Sethi** Managing Partner i Filing they signed

We also hold **7** people at this firm from the lists this database was built from: a weaker source than the filings, since a list does not say when a title ended. Login to see them.

## What the register says

From the firm's own filings with the SEC, which it must file accurately by law

**$226M** gross assets of its funds Oct 2026

**Exempt** reporting adviser venture or small private funds

- **Legal name:** 2048 Ventures, LLC
- **SEC number:** CRD 305237

New fund on file

**$82M**

raised in Mar 2026

From its SEC filing, not a journalist: a firm that has just raised has money to deploy.

## The cheque

Pre-seed

Median round joined **$3.8M** the round, not its cheque Alone, median **$1.1M**

Led 1 of 61 rounds **2%**

- **Said size:** $300K – $2.0M
- **Sole investor:** 9 rounds
- **Last cheque:** Sept 2026

Rounds by stage said on their site

- Seed *19*
- Pre-seed said *16*
- Series A *12*
- Venture *10*
- Growth *1*

Cheques by month Led Joined

Nov 2023 Oct 2026

Often in the room with

- [Flybridge](https://millionrounds.com/fund/flybridge) 5
- [Everywhere Ventures](https://millionrounds.com/fund/everywhere-ventures) 4
- [Plug and Play](https://millionrounds.com/fund/plug-and-play) 4
- [FJ Labs](https://millionrounds.com/fund/fj-labs) 3
- [Gaingels](https://millionrounds.com/fund/gaingels) 3
- [Matchstick Ventures](https://millionrounds.com/fund/matchstick-ventures) 3

**Pitching 2048 Ventures?** Put them on your fundraising board with this record on the card, and follow them to hear when they write a new cheque.

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## Who they invest alongside

The investors most often in the same rounds as 2048 Ventures. A count of rooms they were both in, not a relationship either has claimed.

[**Flybridge** VC firm **5** rounds together](https://millionrounds.com/fund/flybridge)[**Everywhere Ventures** VC firm **4** rounds together](https://millionrounds.com/fund/everywhere-ventures)[**Plug and Play** Accelerator **4** rounds together](https://millionrounds.com/fund/plug-and-play)[**FJ Labs** VC firm **3** rounds together](https://millionrounds.com/fund/fj-labs)[**Gaingels** Private equity **3** rounds together](https://millionrounds.com/fund/gaingels)[**Matchstick Ventures** VC firm **3** rounds together](https://millionrounds.com/fund/matchstick-ventures)[**Techstars** VC firm **3** rounds together](https://millionrounds.com/fund/techstars)[**Y Combinator** Accelerator **3** rounds together](https://millionrounds.com/fund/y-combinator)[**Alumni Ventures** VC firm **2** rounds together](https://millionrounds.com/fund/us-strategic-tech-fund-an-alumni-ventures-fund)[**Better Tomorrow Ventures** VC firm **2** rounds together](https://millionrounds.com/fund/better-tomorrow-ventures)[**Boost VC** VC firm **2** rounds together](https://millionrounds.com/fund/boost-vc)[**Draper Associates** VC firm **2** rounds together](https://millionrounds.com/fund/draper-associates)

## Recently backed

The latest companies 2048 Ventures put money into.

[**TwoStep Therapeutics** $63M · Sept 2026](https://millionrounds.com/company/twostep-therapeutics)[**Genius AI** $44M · Jul 2026](https://millionrounds.com/company/genius-ai)[**Nebex** $30M · Jul 2026](https://millionrounds.com/company/nebex)[**Wirestock** $23M · May 2026](https://millionrounds.com/company/wirestock)[**Century Health** $5.0M · May 2026](https://millionrounds.com/company/century-health)[**Fazeshift** $4.0M · May 2026](https://millionrounds.com/company/fazeshift)

## Quick answers about 2048 Ventures

### What does 2048 Ventures invest in?

2048 Ventures invests most often at Seed and Pre-seed (60% of the rounds on record), in sectors such as Pharmaceuticals, Artificial Intelligence and Therapeutics.

### How active is 2048 Ventures?

61 investments on record, 9 of them in the last 12 months, and it led 1. The most recent was in Sept 2026.

### What has 2048 Ventures invested in recently?

Its most recent investments on record: TwoStep Therapeutics (Series A, Sept 2026), Genius AI (Growth, Jul 2026) and Nebex (Seed, Jul 2026).

### How big are 2048 Ventures's cheques?

The median round it joins is $3.8M. It says it writes cheques of $300K to $2.0M.

### Does 2048 Ventures lead rounds?

Sometimes: it led 1 of its 61 investments on record (2%).

### Where does 2048 Ventures invest?

Most of the companies it backs are in the United States (80%) and Canada (15%).

### Is 2048 Ventures investing now?

Yes: it is actively investing, with 9 investments in the last 12 months.

### Who does 2048 Ventures invest alongside?

Most often Flybridge (5 rounds together), Everywhere Ventures (4 rounds together) and Plug and Play (4 rounds together).

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