# Spyre Therapeutics funding: rounds and investors

> Spyre Therapeutics has raised $678M across 2 rounds since 2025. Investors include Perceptive Advisors, Cormorant Asset Management and RTW Investments LLC.

Source: https://millionrounds.com/company/spyre-therapeutics (Millionrounds; every figure on the page links to its filing or article)

United States · [Funded startup](https://millionrounds.com/companies)

# Who invested in *Spyre Therapeutics*

2 rounds we have observed, with the 4 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

Biotech

Raised 7 months ago

Funding summary Updated 26 Oct 2026

**$678M** raised across 2 rounds since 2025, from 2 sources

**$275M** Round **$403M** Round

- **Latest round:** Round, $403M Apr 2026
- **Step-up i:** 1.5×
- **Investors:** 4

See who backed them

## The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

2026

**$275M** Round

**$403M** Round

- **First round:** Round, $275M
- **Biggest round:** $403M
- **Between rounds:** 6 months

## The rounds

- **Apr 2026** Round **$403M** *4 returning* [Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) [Cormorant Asset Management](https://millionrounds.com/fund/cormorant-asset-management) [RTW Investments LLC](https://millionrounds.com/fund/rtw-investments-lp) [Adage Capital Management](https://millionrounds.com/fund/adage-capital-management) Source recorded
- **Oct 2025** Round **$275M** *4 new* [Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) [Cormorant Asset Management](https://millionrounds.com/fund/cormorant-asset-management) [RTW Investments LLC](https://millionrounds.com/fund/rtw-investments-lp) [Adage Capital Management](https://millionrounds.com/fund/adage-capital-management) Source recorded

## Founders and team

From Spyre Therapeutics's own website and the SEC filings it signed: 6 on the team.

- **Cameron Turtle** Chief Executive Officer
- **Brian Connolly** Chief Technical Officer
- **Kate Tansey Chevlen** Chief Commercial Officer
- **Sheldon Sloan** Chief Medical Officer
- **Heidy King-Jones** Chief Legal Officer and Corporate Secretary
- **Scott Burrows** Chief Financial Officer

On the board, as filed i *Alison J. Lawton* *Jeffrey W. Albers* *Laurie J. Stelzer* *Michael J. Henderson* *Peter J. Harwin* *Russell J. Cox* *Tomas J. Kiselak*

## Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

**Round** 2025 **Round** 2026 [Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) [Cormorant Asset Management](https://millionrounds.com/fund/cormorant-asset-management) [RTW Investments LLC](https://millionrounds.com/fund/rtw-investments-lp) [Adage Capital Management](https://millionrounds.com/fund/adage-capital-management)

## Everyone who backed them

[Perceptive Advisors](https://millionrounds.com/fund/perceptive-advisors) Asset manager **2** rounds

[Cormorant Asset Management](https://millionrounds.com/fund/cormorant-asset-management) Private equity **2** rounds

[RTW Investments LLC](https://millionrounds.com/fund/rtw-investments-lp) Growth equity **2** rounds

[Adage Capital Management](https://millionrounds.com/fund/adage-capital-management) Asset manager **2** rounds

Missing a round, or an investor who was in one? [Tell us](https://millionrounds.com/corrections?slug=spyre-therapeutics).

## Quick answers about Spyre Therapeutics

### Who invested in Spyre Therapeutics?

Spyre Therapeutics's investors include Perceptive Advisors, Cormorant Asset Management, RTW Investments LLC and Adage Capital Management.

### How much has Spyre Therapeutics raised?

Spyre Therapeutics has raised $678M across 2 rounds since 2025.

### When did Spyre Therapeutics last raise?

Spyre Therapeutics's most recent round was an Undisclosed round of $403M in Apr 2026.

### What was Spyre Therapeutics's biggest round?

Its most recent round, $403M in Apr 2026, is also its largest on record.

### Who backed Spyre Therapeutics first?

Spyre Therapeutics's first round on record, in Oct 2025, was backed by Perceptive Advisors, Cormorant Asset Management and RTW Investments LLC and 1 others.

### What stage is Spyre Therapeutics at?

Spyre Therapeutics's latest named round is an Undisclosed round, in Apr 2026.

### Where is Spyre Therapeutics based?

Spyre Therapeutics is based in the United States.

## Companies like Spyre Therapeutics

In the same sector, and raised in the last eighteen months.

[**Star Therapeutics** $325M · Oct 2026](https://millionrounds.com/company/star-therapeutics)[**Promaxo** $106M · Oct 2026](https://millionrounds.com/company/promaxo)[**Prolific Machines** $105M · Oct 2026](https://millionrounds.com/company/prolific-machines)[**IMIO** $19M · Oct 2026](https://millionrounds.com/company/imio)[**Clinical Ink** $24M · Oct 2026](https://millionrounds.com/company/clinical-ink)[**Rejuvenate Bio** $13M · Oct 2026](https://millionrounds.com/company/rejuvenate-bio)

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