# Spruce Biosciences funding: rounds and investors

> Spruce Biosciences has raised $60M across 2 rounds since 2026. Investors include Novo Holdings, Omega Funds and Sands Capital Ventures.

Source: https://millionrounds.com/company/spruce-biosciences (Millionrounds; every figure on the page links to its filing or article)

United States · [Funded startup](https://millionrounds.com/companies)

# Who invested in *Spruce Biosciences*

2 rounds we have observed, with the 4 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

Pharma

Raised 7 months ago

Funding summary Updated 26 Oct 2026

**$60M** raised across 2 rounds since 2026, from 2 sources

- **Latest round:** Round, $60M Apr 2026
- **Investors:** 4

See who backed them

## The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

2026 2027

**?** Venture

**$60M** Round

- **First round:** Venture
- **Biggest round:** $60M
- **Between rounds:** 3 months

## The rounds

- **Apr 2026** Round **$60M** *3 returning* [Novo Holdings](https://millionrounds.com/fund/novo-ventures) [Omega Funds](https://millionrounds.com/fund/omega-funds) [Sands Capital Ventures](https://millionrounds.com/fund/sands-capital-ventures) Source recorded
- **Jan 2026** Venture **Amount undisclosed** *4 new* [Novo Holdings](https://millionrounds.com/fund/novo-ventures) [5AM Ventures](https://millionrounds.com/fund/5am-ventures) [Omega Funds](https://millionrounds.com/fund/omega-funds) [Sands Capital Ventures](https://millionrounds.com/fund/sands-capital-ventures) Source recorded SEC filing: $50M sold, first sale Oct 2025

## Founders and team

From Spruce Biosciences's own website: 2 on the team.

- **Close Modal** Chief Executive Officer
- **Michael Grey** Executive Chairman

## Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

**Venture** 2026 **Round** 2026 [Novo Holdings](https://millionrounds.com/fund/novo-ventures) [Omega Funds](https://millionrounds.com/fund/omega-funds) [Sands Capital Ventures](https://millionrounds.com/fund/sands-capital-ventures) [5AM Ventures](https://millionrounds.com/fund/5am-ventures)

## Everyone who backed them

[Novo Holdings](https://millionrounds.com/fund/novo-ventures) VC firm **2** rounds

[Omega Funds](https://millionrounds.com/fund/omega-funds) VC firm **2** rounds

[Sands Capital Ventures](https://millionrounds.com/fund/sands-capital-ventures) Private equity **2** rounds

[5AM Ventures](https://millionrounds.com/fund/5am-ventures) VC firm **1** round

Missing a round, or an investor who was in one? [Tell us](https://millionrounds.com/corrections?slug=spruce-biosciences).

## Also claim to have backed them

These 2 firms list Spruce Biosciences as a portfolio company on their own websites, but no report of a round names them. They are the firms' own claims, kept apart from the rounds above.

[Aisling Capital](https://millionrounds.com/fund/aisling-capital) Private equity Per its own site

[HealthCap](https://millionrounds.com/fund/healthcap) VC firm Per its own site

## Quick answers about Spruce Biosciences

### Who invested in Spruce Biosciences?

Spruce Biosciences's investors include Novo Holdings, Omega Funds, Sands Capital Ventures and 5AM Ventures.

### How much has Spruce Biosciences raised?

Spruce Biosciences has raised $60M across 2 rounds since 2026. One round did not disclose an amount, so the total is a floor.

### When did Spruce Biosciences last raise?

Spruce Biosciences's most recent round was an Undisclosed round of $60M in Apr 2026.

### What was Spruce Biosciences's biggest round?

Its most recent round, $60M in Apr 2026, is also its largest on record.

### Who backed Spruce Biosciences first?

Spruce Biosciences's first round on record, in Jan 2026, was backed by Novo Holdings, 5AM Ventures and Omega Funds and 1 others.

### What stage is Spruce Biosciences at?

Spruce Biosciences's latest named round is an Undisclosed round, in Apr 2026.

### Where is Spruce Biosciences based?

Spruce Biosciences is based in the United States.

## Companies like Spruce Biosciences

In the same sector, and raised in the last eighteen months.

[**Matchpoint Therapeutics** $220M · Oct 2026](https://millionrounds.com/company/matchpoint-therapeutics)[**Rx Bandz** Oct 2026](https://millionrounds.com/company/rx-bandz)[**Hera Biotech** $1.8M · Sept 2026](https://millionrounds.com/company/hera-biotech)[**GevRx Nutraceuticals** $300K · Sept 2026](https://millionrounds.com/company/gevrx-nutraceuticals)[**RegCell** $81M · Sept 2026](https://millionrounds.com/company/regcell)[**ClearSight Therapeutics** $307K · Sept 2026](https://millionrounds.com/company/clearsight-therapeutics)

## Find investors like these

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