# Denali Therapeutics funding: rounds and investors

> Denali Therapeutics has raised $547M across 3 rounds since 2015. Investors include ARCH Venture Partners, Google Ventures and Eight Roads Ventures.

Source: https://millionrounds.com/company/denali-therapeutics (Millionrounds; every figure on the page links to its filing or article)

United States · [Funded startup](https://millionrounds.com/companies)

# Who invested in *Denali Therapeutics*

3 rounds we have observed, with the 8 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

Biotech Healthcare

Raised 11 months ago

Funding summary Updated 26 Oct 2026

**$547M** raised across 3 rounds since 2015, from 3 sources

**$217M** Series A **$130M** Series B **$200M** Debt

- **Latest round:** Debt, $200M Dec 2025
- **Biggest round:** $217M Series A · May 2015
- **Step-up i:** 1.5×
- **Investors:** 8

See who backed them

## The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

2015 2017 2019 2021 2023 2025

**$217M** Series A

**$130M** Series B

**$200M** Debt

- **First round:** Series A, $217M
- **Biggest round:** $217M
- **Usual gap between rounds:** 9.3 years

## The rounds

- **Dec 2025** Debt **$200M** *3 new* *1 returning* [Google Ventures](https://millionrounds.com/fund/gv) [ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) [Eight Roads Ventures](https://millionrounds.com/fund/eight-roads) [Flagship Pioneering](https://millionrounds.com/fund/flagship-pioneering) Source recorded
- **Aug 2016** Series B **$130M** *1 new* [Baillie Gifford](https://millionrounds.com/fund/baillie-gifford) Reported by FinSMEs
- **May 2015** Series A **$217M** *4 new* [ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) [F-Prime Capital](https://millionrounds.com/fund/f-prime) [Flagship Ventures](https://millionrounds.com/fund/flagship-ventures) [Alaska Permanent Fund Corporation](https://millionrounds.com/fund/alaska-permanent-fund-corporation) From a historical funding record

## Founders and team

From the SEC filings it signed: 3 on the team.

- **Alexander O. Schuth** Executive Officer i
- **Carole O. Ho** Executive Officer i
- **Ryan Watts** Executive Officer, Director i

On the board, as filed i *David P. Schenkein* *Erik T. Harris* *Jay T. Flatley* *Jennifer O. Cook* *Marc P. Tessier-Lavigne* *Nancy A. Thornberry* *Peter S. Klein* *Steve E. Krognes* *Vicki L. Sato*

## Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

**Series A** 2015 **Series B** 2016 **Debt** 2025 [ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) [Google Ventures](https://millionrounds.com/fund/gv) [Eight Roads Ventures](https://millionrounds.com/fund/eight-roads) [F-Prime Capital](https://millionrounds.com/fund/f-prime) [Baillie Gifford](https://millionrounds.com/fund/baillie-gifford) [Flagship Ventures](https://millionrounds.com/fund/flagship-ventures) [Flagship Pioneering](https://millionrounds.com/fund/flagship-pioneering) [Alaska Permanent Fund Corporation](https://millionrounds.com/fund/alaska-permanent-fund-corporation)

## Everyone who backed them

[ARCH Venture Partners](https://millionrounds.com/fund/arch-venture-partners) VC firm **2** rounds

[Google Ventures](https://millionrounds.com/fund/gv) Corporate VC **1** round

[Eight Roads Ventures](https://millionrounds.com/fund/eight-roads) VC firm **1** round

[F-Prime Capital](https://millionrounds.com/fund/f-prime) VC firm **1** round

[Baillie Gifford](https://millionrounds.com/fund/baillie-gifford) Asset manager **1** round

[Flagship Ventures](https://millionrounds.com/fund/flagship-ventures) Accelerator **1** round

[Flagship Pioneering](https://millionrounds.com/fund/flagship-pioneering) VC firm **1** round

[Alaska Permanent Fund Corporation](https://millionrounds.com/fund/alaska-permanent-fund-corporation) Institutional LP **1** round

Missing a round, or an investor who was in one? [Tell us](https://millionrounds.com/corrections?slug=denali-therapeutics).

## Also claim to have backed them

These 2 firms list Denali Therapeutics as a portfolio company on their own websites, but no report of a round names them. They are the firms' own claims, kept apart from the rounds above.

[EcoR1 Capital](https://millionrounds.com/fund/ecor1-capital) Private equity Per its own site

[Blake Byers](https://millionrounds.com/fund/blake-byers) Angel Per its own site

## Quick answers about Denali Therapeutics

### Who invested in Denali Therapeutics?

Denali Therapeutics's investors include ARCH Venture Partners, Google Ventures, Eight Roads Ventures, F-Prime Capital and Baillie Gifford, and 3 more on record.

### How much has Denali Therapeutics raised?

Denali Therapeutics has raised $547M across 3 rounds since 2015.

### When did Denali Therapeutics last raise?

Denali Therapeutics's most recent round was a Debt of $200M in Dec 2025.

### What was Denali Therapeutics's biggest round?

Denali Therapeutics's largest round on record is $217M (Series A), in May 2015.

### Who backed Denali Therapeutics first?

Denali Therapeutics's first round on record, in May 2015, was backed by ARCH Venture Partners, F-Prime Capital and Flagship Ventures and 1 others.

### What stage is Denali Therapeutics at?

Denali Therapeutics's latest named round is a Debt, in Dec 2025.

### Where is Denali Therapeutics based?

Denali Therapeutics is based in the United States.

## Companies like Denali Therapeutics

In the same sector, and raised in the last eighteen months.

[**Star Therapeutics** $325M · Oct 2026](https://millionrounds.com/company/star-therapeutics)[**Promaxo** $106M · Oct 2026](https://millionrounds.com/company/promaxo)[**Prolific Machines** $105M · Oct 2026](https://millionrounds.com/company/prolific-machines)[**AI** $18M · Oct 2026](https://millionrounds.com/company/ai)[**Baba** $40M · Oct 2026](https://millionrounds.com/company/baba)[**IMIO** $19M · Oct 2026](https://millionrounds.com/company/imio)

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