# Actuate Therapeutics funding: rounds and investors > Actuate Therapeutics has raised $122M across 2 rounds since 2019. Investors include Tech Coast Angels, Kairos Ventures and DEFTA Partners. Source: https://millionrounds.com/company/actuate-therapeutics (Millionrounds; every figure on the page links to its filing or article) United States · [Funded startup](https://millionrounds.com/companies) # Who invested in *Actuate Therapeutics* 2 rounds we have observed, with the 4 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it. Biotech Healthcare Raised 12 months ago Funding summary Updated 26 Oct 2026 **$122M** raised across 2 rounds since 2019, from 2 sources **$22M** Series B **$100M** Round - **Latest round:** Round, $100M Nov 2025 - **Step-up i:** 4.6× - **Investors:** 4 (1 led) See who backed them ## The funding story Each circle is a round, placed by date and sized by amount. The line above is the running total. 2019 2020 2021 2022 2023 2024 2025 **$22M** Series B **$100M** Round - **First round:** Series B, $22M - **Biggest round:** $100M - **Between rounds:** 6.5 years ## The rounds - **Nov 2025** Round **$100M** *1 returning* [Tech Coast Angels](https://millionrounds.com/fund/tech-coast-angels) Source recorded SEC filing: $4.7M sold, first sale Jun 2025 - **May 2019** Series B **$22M** *4 new* [Kairos Ventures](https://millionrounds.com/fund/kairos-ventures) Lead [Tech Coast Angels](https://millionrounds.com/fund/tech-coast-angels) [DEFTA Partners](https://millionrounds.com/fund/defta-partners) [Bios Partners](https://millionrounds.com/fund/bios-partners) Reported by FinSMEs SEC filing: $22M sold, first sale Apr 2019 ## Founders and team From Actuate Therapeutics's own website: 9 on the team. - **Daniel M. Schmitt** President & Chief Executive Officer - **Chris Seifarth** Vice President, Operations and Quality Assurance - **Paul Lytle** Chief Financial Officer - **Amy Ronneberg** Director - **Carrie Kellinger** Senior Director, Operations - **Jason Keyes** Director - **Roger Sawhney** Director - **Sarah Majka** Senior Manager, Clinical Operations - **Todd Thomson** Director ## Who was in which round The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led. **Series B** 2019 **Round** 2025 [Tech Coast Angels](https://millionrounds.com/fund/tech-coast-angels) [Kairos Ventures](https://millionrounds.com/fund/kairos-ventures) L [DEFTA Partners](https://millionrounds.com/fund/defta-partners) [Bios Partners](https://millionrounds.com/fund/bios-partners) ## Everyone who backed them [Tech Coast Angels](https://millionrounds.com/fund/tech-coast-angels) VC firm **2** rounds [Kairos Ventures](https://millionrounds.com/fund/kairos-ventures) VC firm **1** round, led 1 [DEFTA Partners](https://millionrounds.com/fund/defta-partners) VC firm **1** round [Bios Partners](https://millionrounds.com/fund/bios-partners) Private equity **1** round Missing a round, or an investor who was in one? [Tell us](https://millionrounds.com/corrections?slug=actuate-therapeutics). ## Also claim to have backed them These 2 firms list Actuate Therapeutics as a portfolio company on their own websites, but no report of a round names them. They are the firms' own claims, kept apart from the rounds above. [Illinois Ventures](https://millionrounds.com/fund/illinois-ventures) Government Per its own site [SeedFolio](https://millionrounds.com/fund/seedfolio) VC firm Per its own site ## Quick answers about Actuate Therapeutics ### Who invested in Actuate Therapeutics? Actuate Therapeutics's investors include Tech Coast Angels, Kairos Ventures, DEFTA Partners and Bios Partners. ### How much has Actuate Therapeutics raised? Actuate Therapeutics has raised $122M across 2 rounds since 2019. ### When did Actuate Therapeutics last raise? Actuate Therapeutics's most recent round was an Undisclosed round of $100M in Nov 2025. ### What was Actuate Therapeutics's biggest round? Its most recent round, $100M in Nov 2025, is also its largest on record. ### Who backed Actuate Therapeutics first? Actuate Therapeutics's first round on record, in May 2019, was backed by Kairos Ventures, Tech Coast Angels and DEFTA Partners and 1 others. ### What stage is Actuate Therapeutics at? Actuate Therapeutics's latest named round is an Undisclosed round, in Nov 2025. ### Where is Actuate Therapeutics based? Actuate Therapeutics is based in the United States. ### Who led Actuate Therapeutics's rounds? Kairos Ventures led the Series B in 2019. ## Companies like Actuate Therapeutics In the same sector, and raised in the last eighteen months. [**Star Therapeutics** $325M · Oct 2026](https://millionrounds.com/company/star-therapeutics)[**Promaxo** $106M · Oct 2026](https://millionrounds.com/company/promaxo)[**Prolific Machines** $105M · Oct 2026](https://millionrounds.com/company/prolific-machines)[**AI** $18M · Oct 2026](https://millionrounds.com/company/ai)[**Baba** $40M · Oct 2026](https://millionrounds.com/company/baba)[**IMIO** $19M · Oct 2026](https://millionrounds.com/company/imio) ## Find investors like these Search every investor by what they have actually funded, then narrow to your stage and market. Free. Open the investor searchOr these rounds in the app